Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Doraiswami Ramkrishna"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 748-757 (2023)
Abstract Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and fetal hemoglobin level over time. We m
Externí odkaz:
https://doaj.org/article/8bb3d8e5d53948adb9939375aef6d166
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The in-depth understanding of the dynamics of COVID-19 transmission among different age groups is of great interest for governments and health authorities so that strategies can be devised to reduce the pandemic’s detrimental effects. We d
Externí odkaz:
https://doaj.org/article/1463a11727bd4ebc946e588346f736c6
Autor:
Shiyan Wang, Doraiswami Ramkrishna
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Considering looming fatality and economic recession, effective policy making based on ongoing COVID-19 pandemic is an urgent and standing issue. Numerous issues for controlling infection have arisen from public discussion led by medical prof
Externí odkaz:
https://doaj.org/article/da1b9e03eb8741db92e849b66995be84
Autor:
You-Yeon Won, Doraiswami Ramkrishna
Publikováno v:
ACS Omega, Vol 5, Iss 51, Pp 33484-33487 (2020)
Externí odkaz:
https://doaj.org/article/bf81e92c9fb44bd7af6717a1c40ff346
Autor:
You-Yeon Won, Doraiswami Ramkrishna
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 11215-11222 (2019)
Externí odkaz:
https://doaj.org/article/bfe86a5a66414a9f90a27eb163590512
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1065 (2022)
Sickle cell disease (SCD) is a chronic hemolytic anemia affecting millions worldwide with acute and chronic clinical manifestations and early mortality. While hydroxyurea (HU) and other treatment strategies managed to ameliorate disease severity, hig
Externí odkaz:
https://doaj.org/article/39b5df82759249789cc8e72b009c9624
Autor:
Parul Verma, Muriel Eaton, Achim Kienle, Dietrich Flockerzi, Yang Yang, Doraiswami Ramkrishna
Publikováno v:
Frontiers in Computational Neuroscience, Vol 14 (2020)
Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent, painful side effect which arises due to a number of chemotherapy agents. CIPN can have a prolonged effect on quality of life. Chemotherapy treatment is often reduced or stopped altoget
Externí odkaz:
https://doaj.org/article/a3651428950f40d3b864dc6e9e226144
Autor:
Devaraj Jayachandran, José Laínez-Aguirre, Ann Rundell, Terry Vik, Robert Hannemann, Gintaras Reklaitis, Doraiswami Ramkrishna
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133244 (2015)
6-Mercaptopurine (6-MP) is one of the key drugs in the treatment of many pediatric cancers, auto immune diseases and inflammatory bowel disease. 6-MP is a prodrug, converted to an active metabolite 6-thioguanine nucleotide (6-TGN) through enzymatic r
Externí odkaz:
https://doaj.org/article/336c7cb46eb047bbaae3a53985e7944f
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109623 (2014)
Acute Lymphoblastic Leukemia, commonly known as ALL, is a predominant form of cancer during childhood. With the advent of modern healthcare support, the 5-year survival rate has been impressive in the recent past. However, long-term ALL survivors emb
Externí odkaz:
https://doaj.org/article/707610e9b43648f7acbc6b11ee60d568
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79196 (2013)
There is increasing recognition that stochasticity involved in gene regulatory processes may help cells enhance the signal or synchronize expression for a group of genes. Thus the validity of the traditional deterministic approach to modeling the for
Externí odkaz:
https://doaj.org/article/6c937205547244898ac4577a887d880a