Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study

Autor: Bassols-Casadevall J, Martínez-Calcerrada JM, Osiniri I, Díaz-Roldán F, Xargay-Torrent S, Mas-Parés B, Dorado-Ceballos E, Prats A, Carreras-Badosa G, de Zegher F, Ibañez-Toda L, López-Bermejo A

Publikováno v: PLoS One
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

BACKGROUND: Metformin treatment (1000-2000 mg/day) over 6 months in pubertal children and/or adolescents with obesity and hyperinsulinism is associated with a reduction in body mass index (BMI) and the insulin resistance index (HOMA-IR). We aimed to

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http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16989

Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study.

Autor: Bassols J; Maternal-Fetal Metabolic Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain., Martínez-Calcerrada JM; Maternal-Fetal Metabolic Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain., Osiniri I; Clinical Laboratory, Salut Empordà Foundation, Figueres, Spain., Díaz-Roldán F; Pediatrics, Dr. Trueta University Hospital, Girona, Spain., Xargay-Torrent S; Pediatric Endocrinology Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain., Mas-Parés B; Maternal-Fetal Metabolic Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain., Dorado-Ceballos E; Pediatrics, Dr. Trueta University Hospital, Girona, Spain., Prats-Puig A; Department of Physical Therapy, EUSES University School, University of Girona, Girona, Spain., Carreras-Badosa G; Pediatric Endocrinology Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain., de Zegher F; Department of Development & Regeneration, University of Leuven, Leuven, Belgium., Ibáñez L; Endocrinology, Pediatric Research Institute, Sant Joan de Déu Children's Hospital, Barcelona, Spain.; [Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders] CIBERDEM, ISCIII, Madrid, Spain., López-Bermejo A; Pediatrics, Dr. Trueta University Hospital, Girona, Spain.; Pediatric Endocrinology Group, [Girona Biomedical Research Institute] IDIBGI, Salt, Spain.

Publikováno v: PloS one [PLoS One] 2019 Dec 10; Vol. 14 (12), pp. e0226303. Date of Electronic Publication: 2019 Dec 10 (Print Publication: 2019).