Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Dora Tang"'
Publikováno v:
eLife, Vol 12 (2023)
Condensed coacervate phases are now understood to be important features of modern cell biology, as well as valuable protocellular models in origin-of-life studies and synthetic biology. In each of these fields, the development of model systems with v
Externí odkaz:
https://doaj.org/article/4855d398eb9a49c08c02741b3f99662d
Autor:
Adrian Zambrano, Giorgio Fracasso, Mengfei Gao, Martina Ugrinic, Dishi Wang, Dietmar Appelhans, Andrew deMello, T-Y. Dora Tang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Our understanding of how compartmentalisation and intercellular communication can tune enzyme reactions is still in its infancy. Here, the authors show that multi-enzyme reactions within semi-permeable compartments have distinct properties compared t
Externí odkaz:
https://doaj.org/article/9a07094325254dbe8bdb7d53a21aadb9
Autor:
Nino Lauber, Ondrej Tichacek, Rudrarup Bose, Christoph Flamm, Luca Leuzzi, T-Y Dora Tang, Kepa Ruiz-Mirazo, Daniele De Martino
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106300- (2023)
Summary: Physical mechanisms of phase separation in living systems play key physiological roles and have recently been the focus of intensive studies. The strongly heterogeneous nature of such phenomena poses difficult modeling challenges that requir
Externí odkaz:
https://doaj.org/article/3877b7526eb14139988ef31c4b2d3f35
Autor:
Damian Wollny, Benjamin Vernot, Jie Wang, Maria Hondele, Aram Safrastyan, Franziska Aron, Julia Micheel, Zhisong He, Anthony Hyman, Karsten Weis, J. Gray Camp, T.‐Y. Dora Tang, Barbara Treutlein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here, the authors demonstrate that single cell RNA sequencing technology can be leveraged to characterize RNA content of individual membrane-free condensates formed by liquid-liquid phase separation processes such as coacervation.
Externí odkaz:
https://doaj.org/article/48b715e11b9444c0bb85084287f0da15
Autor:
Lars Hubatsch, Louise M Jawerth, Celina Love, Jonathan Bauermann, TY Dora Tang, Stefano Bo, Anthony A Hyman, Christoph A Weber
Publikováno v:
eLife, Vol 10 (2021)
Key processes of biological condensates are diffusion and material exchange with their environment. Experimentally, diffusive dynamics are typically probed via fluorescent labels. However, to date, a physics-based, quantitative framework for the dyna
Externí odkaz:
https://doaj.org/article/eb40ee1913f644cab05a643ca5e29dae
Autor:
Thomas E. Gorochowski, Sabine Hauert, Jan-Ulrich Kreft, Lucia Marucci, Namid R. Stillman, T.-Y. Dora Tang, Lucia Bandiera, Vittorio Bartoli, Daniel O. R. Dixon, Alex J. H. Fedorec, Harold Fellermann, Alexander G. Fletcher, Tim Foster, Luca Giuggioli, Antoni Matyjaszkiewicz, Scott McCormick, Sandra Montes Olivas, Jonathan Naylor, Ana Rubio Denniss, Daniel Ward
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Many complex behaviors in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are of great interest to bioengineer
Externí odkaz:
https://doaj.org/article/1690bd498c644b809310d629489f45c1
Autor:
Björn Drobot, Juan M. Iglesias-Artola, Kristian Le Vay, Viktoria Mayr, Mrityunjoy Kar, Moritz Kreysing, Hannes Mutschler, T-Y Dora Tang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Phase separation of mixtures of oppositely charged polymers provides a simple and direct route to compartmentalisation via coacervation. Here authors demonstrate that a coacervate microenvironment supports RNA catalysis whilst selectively sequesterin
Externí odkaz:
https://doaj.org/article/ffa9ae58dd1c47ec95dba2093bd693d4
Autor:
T.‐Y. Dora Tang, Avinash J. Patil
Publikováno v:
ChemSystemsChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97074eb0fe8c79db86e433eafa2979c8
https://doi.org/10.1002/syst.202300007
https://doi.org/10.1002/syst.202300007
Building synthetic multicellular systems using non-living molecular components is a grand challenge in the field of bottom-up synthetic biology. Towards this goal, a diverse range of chemistries have been developed to provide mechanisms of intercellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7bf82d478f9936affc839e43be2c04
https://doi.org/10.1101/2023.03.04.531082
https://doi.org/10.1101/2023.03.04.531082
Autor:
Ianeselli, Alan, Tetiker, Damla, Stein, Julian, Kühnlein, Alexandra, Mast, Christof B., Braun, Dieter, Dora Tang, T.-Y.
Publikováno v:
Nature Chemistry; 20240101, Issue: Preprints p1-8, 8p