Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dora Posfai"'
Autor:
Kayla Sylvester, Steven P. Maher, Dora Posfai, Michael K. Tran, McKenna C. Crawford, Amélie Vantaux, Benoît Witkowski, Dennis E. Kyle, Emily R. Derbyshire
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Plasmodium is a genus of apicomplexan parasites which replicate in the liver before causing malaria. Plasmodium vivax can also persist in the liver as dormant hypnozoites and cause clinical relapse upon activation, but the molecular mechanisms leadin
Externí odkaz:
https://doaj.org/article/eb61cd7ba2e44e8685764525ca944d4d
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT The apicomplexan parasites Plasmodium spp. are the causative agents of malaria, a disease that poses a significant global health burden. Plasmodium spp. initiate infection of the human host by transforming and replicating within hepatocytes.
Externí odkaz:
https://doaj.org/article/453cc204e3344120afb0e2bde561d652
Autor:
Pamela J. Windsor Reid, Eugueni Matveev, Alexandra McClymont, Dora Posfai, April L. Hill, Sally P. Leys
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The Wnt signaling pathway is uniquely metazoan and used in many processes during development, including the formation of polarity and body axes. In sponges, one of the earliest diverging animal groups, Wnt pathway genes have diver
Externí odkaz:
https://doaj.org/article/07c3e043bdf6453d93961a5249fb9079
Autor:
Chelsea Hall, Melanie Rodriguez, Josephine Garcia, Dora Posfai, Rachel DuMez, Erik Wictor, Omar A Quintero, Malcolm S Hill, Ajna S Rivera, April L Hill
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212005 (2019)
Canonical and non-canonical Wnt signaling, as well as the Pax/Six gene network, are involved in patterning the freshwater sponge aquiferous system. Using computational approaches to identify transcription factor binding motifs in a freshwater sponge
Externí odkaz:
https://doaj.org/article/94f720792c7b4dbaaecbd757af160217
Autor:
Dora Posfai, Kayla Sylvester, Anupama Reddy, Jack G Ganley, Johannes Wirth, Quinlan E Cullen, Tushar Dave, Nobutaka Kato, Sandeep S Dave, Emily R Derbyshire
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007057 (2018)
Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use RNA-sequencing to identify host genes that are upregulated upon Plasmodium berghei infection of hepatocytes with the hypot
Externí odkaz:
https://doaj.org/article/5afc4dbb8588431aaa25768808694a9a
Publikováno v:
Cancer Research. 83:3728-3728
RNA sequencing (RNA-seq) has become an invaluable tool in the study of biology, but often requires multiple days to process samples from total RNA to final libraries that can be loaded on to a sequencer. Researchers use RNA-seq to gain insight into w
Autor:
Emily R. Derbyshire, Steven P. Maher, Benoit Witkowski, Dennis E. Kyle, Kayla Sylvester, Dora Posfai, Michael K. Tran, Amélie Vantaux, McKenna C. Crawford
The apicomplexan Plasmodium parasites replicate in the liver before causing malaria. P. vivax can also persist in the liver as dormant hypnozoites and cause relapses upon activation. The host water and solute channel aquaporin-3 (AQP3) has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a6da9a18fdba48297778581b8cb6d30
https://doi.org/10.1101/2020.12.09.417949
https://doi.org/10.1101/2020.12.09.417949
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03234-19 (2020)
mBio, Vol 11, Iss 1, p e03234-19 (2020)
The apicomplexan parasitesPlasmodiumspp. are the causative agents of malaria, a disease that poses a significant global health burden.Plasmodiumspp. initiate infection of the human host by transforming and replicating within hepatocytes. This liver s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1dc5f1ef56954f1e0753ad71d9993
https://doi.org/10.1101/870030
https://doi.org/10.1101/870030
Autor:
Shengxi Guan, Ivan R. Corrêa, Dora Posfai, Keerthana Krishnan, Alice Blondel, Madalee G. Wulf, Maguire Sean, Nan Dai, Zhiyi Sun
Publikováno v:
Nucleic Acids Research
Template-switching reverse transcription is widely used in RNA sequencing for low-input and low-quality samples, including RNA from single cells or formalin-fixed paraffin-embedded (FFPE) tissues. Previously, we identified the native eukaryotic mRNA
Publikováno v:
Journal of Clinical Investigation. 126:2013-2020
Malaria remains a global public health threat, with half of the world's population at risk. Despite numerous efforts in the past decade to develop new antimalarial drugs to surmount increasing resistance to common therapies, challenges remain in the