Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Dora, Yearout"'
Autor:
Mario Cornejo-Olivas, Luis Torres, Mario R. Velit-Salazar, Miguel Inca-Martinez, Pilar Mazzetti, Carlos Cosentino, Federico Micheli, Claudia Perandones, Elena Dieguez, Victor Raggio, Vitor Tumas, Vanderci Borges, Henrique B. Ferraz, Carlos R. M. Rieder, Artur Shumacher-Schuh, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio, Francisco Lopera, Jorge Chang-Castello, Brennie Andreé-Munoz, Sarah Waldherr, Dora Yearout, Cyrus P. Zabetian, Ignacio F. Mata
Publikováno v:
npj Parkinson's Disease, Vol 3, Iss 1, Pp 1-6 (2017)
Genetic risk: Uncovering ethnic-specific mutations A new study reveals the frequency of Leucine-Rich Repeat Kinase 2 (LRRK2) mutations associated with Parkinson’s disease (PD) in Latin Americans. Ignacio F. Mata at the University of Washington and
Externí odkaz:
https://doaj.org/article/8fc179d0b7984d899f5ac72f47c1dfe8
Autor:
Serdar Kazanci, Jennifer Witt, Kimmy Su, Oswaldo Lorenzo‐Betancor, Dora Yearout, Cyrus P. Zabetian, Marie Y. Davis
Publikováno v:
Movement Disorders Clinical Practice. 10:338-340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33992a98aaa84c2faaac4587750c2ff8
https://doi.org/10.1002/mdc3.13632
https://doi.org/10.1002/mdc3.13632
Autor:
Thiago P Leal, Jennifer N French-Kwawu, Mateus H Gouveia, Victor Borda, Miguel Inca-Martinez, Emily A Mason, Andrea RVR Horimoto, Douglas P Loesch, Elif I Sarihan, Mario R Cornejo-Olivas, Luis E Torres, Pilar E Mazzetti-Soler, Carlos Cosentino, Elison H Sarapura-Castro, Andrea Rivera-Valdivia, Angel C Medina, Elena M Dieguez, Víctor E Raggio, Andrés Lescano, Vitor Tumas, Vanderci Borges, Henrique B Ferraz, Carlos R Rieder, Artur Schumacher-Schuh, Bruno L Santos-Lobato, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio, Francisco Lopera, Sonia Moreno, Pedro Chana-Cuevas, William Fernandez, Gonzalo Arboleda, Humberto Arboleda, Carlos E Arboleda Bustos, Dora Yearout, Maria F Lima-Costa, Eduardo Tarazona, Cyrus Zabetian, Timothy A Thornton, Timothy D O’Connor, Ignacio F Mata
Publikováno v:
medRxiv
Sex differences in Parkinson Disease (PD) risk are well-known. However, it is still unclear the role of sex chromosomes in the development and progression of PD. We performed the first X-chromosome Wide Association Study (XWAS) for PD risk in Latin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611448199f677e7660d221b8a0d775d6
https://europepmc.org/articles/PMC9915833/
https://europepmc.org/articles/PMC9915833/
Autor:
Oswaldo Lorenzo-Betancor, Livio Galosi, Laura Bonfili, Anna Maria Eleuteri, Valentina Cecarini, Ranieri Verin, Fabrizio Dini, Anna-Rita Attili, Sara Berardi, Lucia Biagini, Patrizia Robino, Maria Cristina Stella, Dora Yearout, Michael O. Dorschner, Debby W. Tsuang, Giacomo Rossi, Cyrus P. Zabetian
BackgroundSeveral genetic models that recapitulate neurodegenerative features of Parkinson’s disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51007cdc2c2dd71ab0e300c7c73d9a2d
https://doi.org/10.1101/2022.03.30.483987
https://doi.org/10.1101/2022.03.30.483987
Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body-like Pathology in Parrots
Autor:
Oswaldo Lorenzo‐Betancor, Livio Galosi, Laura Bonfili, Anna Maria Eleuteri, Valentina Cecarini, Ranieri Verin, Fabrizio Dini, Anna‐Rita Attili, Sara Berardi, Lucia Biagini, Patrizia Robino, Maria Cristina Stella, Dora Yearout, Michael O. Dorschner, Debby W. Tsuang, Giacomo Rossi, Cyrus P. Zabetian
Several genetic models that recapitulate neurodegenerative features of Parkinson's disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked to the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e443c247ae1df0725dec44fda8286871
https://hdl.handle.net/11577/3462764
https://hdl.handle.net/11577/3462764
Autor:
Ignacio F. Mata, Artur F. Schumacher-Schuh, Carlos Velez-Pardo, Gonzalo Arboleda, Emily Mason, Andrea R. V. R. Horimoto, Elif Irem Sarihan, Bruno Lopes Santos-Lobato, Carlos Roberto de Mello Rieder, Dora Yearout, Angel C. Medina, Elison Sarapura-Castro, Pedro Chana-Cuevas, Andrea Rivera-Valdivia, Carlos Cosentino, Timothy D. O’Connor, Sonia Moreno, Víctor Raggio, Cyrus P. Zabetian, Timothy A. Thornton, Vitor Tumas, Mario Cornejo-Olivas, Marlene Jimenez-Del-Rio, Miguel Inca-Martinez, Vanderci Borges, Pilar Mazzetti, Carlos E. Arboleda-Bustos, Douglas Loesch, Francisco Lopera, Luis Torres, Humberto Arboleda, Henrique Ballalai Ferraz, Elena Dieguez, William Fernandez, Andres G. Lescano
BackgroundLarge-scale Parkinson’s disease (PD) genome-wide association studies (GWAS) and meta-analyses have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed using PD GWA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::901d5d3a600be69a23d909c2aaeca919
https://doi.org/10.1101/2021.11.09.21265082
https://doi.org/10.1101/2021.11.09.21265082
Autor:
Carlos E. Arboleda-Bustos, Douglas Loesch, Paul Cannon, Francisco Lopera, Carlos Cosentino, Andrea Rivera-Valdivia, Carlos Velez-Pardo, Cyrus P. Zabetian, Mario Cornejo-Olivas, Ignacio F. Mata, Sonia Moreno, Karl Heilbron, Carlos Roberto de Mello Rieder, Miguel Inca-Martinez, Andrea R. V. R. Horimoto, Pilar Mazzetti, Luis Torres, Vanderci Borges, Dora Yearout, Elison Sarapura-Castro, Gonzalo Arboleda, Timothy D. O’Connor, Artur F. Schumacher-Schuh, Elif Irem Sarihan, Bruno Lopes Santos-Lobato, Vitor Tumas, Marlene Jimenez-Del-Rio, Pedro Chana-Cuevas, William Fernandez, Emily Mason, Andres G. Lescano, Humberto Arboleda, Elena Dieguez, Henrique Ballalai Ferraz, Angel C. Medina, Timothy A. Thornton, Víctor Raggio
Publikováno v:
Ann Neurol
OBJECTIVE This work was undertaken in order to identify Parkinson's disease (PD) risk variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in Latinos compared to European-ancestry subjects, and to increase the divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7df57c1d86c1d1326a1208b2e1c60d
https://pubmed.ncbi.nlm.nih.gov/34476843
https://pubmed.ncbi.nlm.nih.gov/34476843
Autor:
Andrea Rivera-Valdivia, Carlos Roberto de Mello Rieder, Víctor Raggio, Emily Mason, Miguel Inca-Martinez, William Fernandez, Angel C. Medina, Paul Cannon, Henrique Ballalai Ferraz, Andres G. Lescano, Pilar Mazzetti, Karl Heilbron, Sonia Moreno, Gonzalo Arboleda, Humberto Arboleda, Timothy D. O’Connor, Carlos E. Arboleda-Bustos, Vanderci Borges, Timothy A. Thornton, Ignacio F. Mata, Bruno Lopes Santos-Lobato, Pedro Chana-Cuevas, Carlos Velez-Pardo, Vitor Tumas, Elena Dieguez, Cyrus P. Zabetian, Douglas Loesch, Francisco Lopera, Marlene Jimenez-Del-Rio, Luis Torres, Dora Yearout, Mario Cornejo-Olivas, Elif Irem Sarihan, Carlos Cosentino, Andrea R. V. R. Horimoto, Elison Sarapura-Castro, Artur F. Schumacher-Schuh
To date, over 90 Parkinson’s disease (PD) risk variants have been reported from genome-wide association studies (GWAS). However, these GWAS efforts have been limited to individuals of European and East Asian ancestry. We performed the first GWAS of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474c573306004b2a7bda8c26bacfcc29
https://doi.org/10.1101/2020.11.09.20227124
https://doi.org/10.1101/2020.11.09.20227124
Autor:
Ali Samii, B. Jane Distad, Cyrus P. Zabetian, Dora Yearout, Ignacio F. Mata, Suman Jayadev, Hojoong M. Kim, Katelan Longfellow, Oswaldo Lorenzo-Betancor, Yi-Han Lin
Publikováno v:
Parkinsonism Relat Disord
Background Mutations in the F-box protein 7 (FBXO7) gene result in autosomal recessive parkinsonism. This usually manifests as early-onset parkinsonian-pyramidal syndrome but patients exhibit high phenotypic variability. Here we describe the findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48cc95c351344300033feb81f66540a
https://pubmed.ncbi.nlm.nih.gov/33002721
https://pubmed.ncbi.nlm.nih.gov/33002721
Autor:
Artur F. Schumacher-Schuh, Dora Yearout, Sonia Moreno, Andrea Rivera-Valdivia, Gonzalo Arboleda, Elena Dieguez, Vanderci Borges, Elison Sarapura-Castro, Lisa-Marie Niestroj, Carlos Roberto de Mello Rieder, Víctor Raggio, Timothy A. Thornton, Pilar Mazzetti, Carlos Velez-Pardo, Cyrus P. Zabetian, Humberto Arboleda, Pedro Chana-Cuevas, Miguel Inca-Martinez, Henrique Ballalai Ferraz, Eduardo Pérez-Palma, Ignacio F. Mata, Timothy D. O’Connor, William Fernandez, Vitor Tumas, Andres G. Lescano, Bruno Lopes Santos-Lobato, Carlos Cosentino, Marlene Jimenez-Del-Rio, Dennis Lal, Carlos E. Arboleda-Bustos, Douglas Loesch, Francisco Lopera, Luis Torres, Elif Irem Sarihan, Mario Cornejo-Olivas, Andrea R. V. R. Horimoto
Background: Parkinson's disease is the second most common neurodegenerative disorder and affects people from all ethnic backgrounds, yet little is known about the genetics of Parkinson's disease in non-European populations. In addition, the overall i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e785beb1f79e87790b58a3384fd80968
https://doi.org/10.1101/2020.05.29.20100859
https://doi.org/10.1101/2020.05.29.20100859