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Mexican calea (Calea zacatechichi Schltdl.) interferes with cholinergic and dopaminergic pathways and causes neuroglial toxicity.

Autor: Garcia MR; REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal; Associate Laboratory i4HB - Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, 4050-313, Portugal; UCIBIO, Laboratory of Toxicology, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal; Associate Laboratory i4HB - Institute for Health and Bioeconomy, University Institute of Health Sciences - CESPU, 4585-116, Gandra, Portugal; UCIBIO - Applied Molecular Biosciences Unit, Forensics and Biomedical Sciences Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116, Gandra, Portugal. Electronic address: ritagarcia7@hotmail.com., Ferreres F; Molecular Recognition and Encapsulation (REM) Group, Department of Food Technology and Nutrition, Universidad Católica de Murcia, 30107, Murcia, Spain. Electronic address: fferreres@ucam.edu., Mineiro T; Associate Laboratory i4HB - Institute for Health and Bioeconomy, University Institute of Health Sciences - CESPU, 4585-116, Gandra, Portugal; UCIBIO - Applied Molecular Biosciences Unit, Forensics and Biomedical Sciences Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116, Gandra, Portugal. Electronic address: tmarquesmineiro@hotmail.com., Videira RA; REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal. Electronic address: rvideira@ff.up.pt., Gil-Izquierdo Á; Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), Campus University Espinardo, 30100, Murcia, Spain. Electronic address: angelgil@cebas.csic.es., Andrade PB; REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal. Electronic address: pandrade@ff.up.pt., Seabra V; Associate Laboratory i4HB - Institute for Health and Bioeconomy, University Institute of Health Sciences - CESPU, 4585-116, Gandra, Portugal; UCIBIO - Applied Molecular Biosciences Unit, Forensics and Biomedical Sciences Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116, Gandra, Portugal. Electronic address: vitor.seabra@iucs.cespu.pt., Dias-da-Silva D; Associate Laboratory i4HB - Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, 4050-313, Portugal; UCIBIO, Laboratory of Toxicology, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal; Associate Laboratory i4HB - Institute for Health and Bioeconomy, University Institute of Health Sciences - CESPU, 4585-116, Gandra, Portugal; UCIBIO - Applied Molecular Biosciences Unit, Forensics and Biomedical Sciences Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116, Gandra, Portugal; LAQV/REQUIMTE, ESS, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal. Electronic address: dds@ess.ipp.pt., Gomes NGM; REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, nº 228, 4050-313, Porto, Portugal. Electronic address: ngomes@ff.up.pt.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Oct 09; Vol. 337 (Pt 3), pp. 118915. Date of Electronic Publication: 2024 Oct 09.

Purified Serum IgG from a Patient with Anti-IgLON5 Antibody Cause Long-Term Movement Disorders with Impaired Dopaminergic Pathways in Mice

Autor: Yining Gao, Hongxia Li, Huoqing Luo, You Ni, Yifan Feng, Lu He, Qinming Zhou, Ji Hu, Sheng Chen

Publikováno v: Biomedicines, Vol 11, Iss 9, p 2483 (2023)

Background: Anti-IgLON5 disease is a rare autoimmune disease of the central nervous system. It typically manifests as a chronic condition, characterized by cognitive impairments, movement disorders, and sleep disorders. The mechanisms underlying move

Externí odkaz: https://doaj.org/article/90a7eed85ca24d9595e43f28f58fb672