Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Dopamine Uptake Complex"'
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 33, Iss 2, Pp 237-240 (2000)
Brazilian Journal of Medical and Biological Research, Volume: 33, Issue: 2, Pages: 237-240, Published: FEB 2000
Brazilian Journal of Medical and Biological Research, Volume: 33, Issue: 2, Pages: 237-240, Published: FEB 2000
Dopamine nigrostriatal neurons are important for motor control and may contain a particularly dense population of ryanodine receptors involved in the control of dopamine release. To test this hypothesis, we used a classical model of unilateral select
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 1996, 205 (3), pp.145-8. ⟨10.1016/0304-3940(96)12399-5⟩
Neuroscience Letters, Elsevier, 1996, 205 (3), pp.145-8. ⟨10.1016/0304-3940(96)12399-5⟩
We have considered the in vivo striatal binding of two ligands of the neuronal dopamine uptake complex: [ 3 H]cocaine and [ 3 H]mazindol. The [ 3 H]cocaine tracer dose labelled the dopamine uptake complex in striatum but not the noradrenaline complex
Publikováno v:
Neurodegeneration. 4:155-160
Synaptosomes, prepared from the striata of mice, and incubated for 1 h in a Krebs-Ringer medium with the peroxidative combination of ascorbic acid (0.1 mM)/Fe2+ (1 microM), lose their ability to take up [3H] dopamine. This effect is associated with a
Publikováno v:
Life Sciences. 55:189-199
It remains controversial whether blood platelet can be used as a peripheral model for the central presynaptic dopaminergic neurons. We investigated the existence of dopamine transport complex in human blood platelet membranes using the selective dopa
Publikováno v:
Neuropharmacology. 30:591-598
The modulation by dopamine of the binding of [3H]BTCP to the dopamine (DA) uptake complex was investigated in vivo (in control, reserpine- and L-DOPA-treated mice) and in vitro (on membrane preparations of the striatum of the rat). In both cases incr
Publikováno v:
Journal of Neurochemistry. 56:553-559
The phencyclidine (PCP) derivative, [3H]N-[1-(2-benzo[b]thiophenyl)cyclohexyl]piperidine ([3H]BTCP), was used to label in vivo the dopamine uptake complex in mouse brain. The striatum accumulated the highest level of total and specific binding. Drugs
Publikováno v:
European Journal of Pharmacology
European Journal of Pharmacology, 1990, 178 (2), pp.221-7. ⟨10.1016/0014-2999(90)90478-o⟩
European Journal of Pharmacology, 1990, 178 (2), pp.221-7. ⟨10.1016/0014-2999(90)90478-o⟩
In mice, low doses (1-2-4 mg/kg s.c.) of dexamphetamine stimulated locomotor activity in a dose-dependent manner. Over the same range of doses the drug dose dependently inhibited the in vivo striatal binding of the dopamine uptake inhibitor, [ 3 H]GB
Publikováno v:
European Journal of Pharmacology. 177:91-94
Although some behavioral effects of cocaine are hypothesized to be due to blockade of dopamine uptake in nucleus accumbens, it has been reported that in nucleus accumbens there are no specific cocaine binding sites and that cocaine is a weak inhibito
Publikováno v:
European Neuropsychopharmacology the Journal of the European College of Neuropsychopharmacology
European Neuropsychopharmacology the Journal of the European College of Neuropsychopharmacology, 1998, 8 (4), pp.255-9. ⟨10.1016/s0924-977x(97)00083-7⟩
European Neuropsychopharmacology the Journal of the European College of Neuropsychopharmacology, 1998, 8 (4), pp.255-9. ⟨10.1016/s0924-977x(97)00083-7⟩
The antimicrobial agent oxolinic acid, injected i.p. in mice, induced a dose dependent increase in locomotor activity. This stimulation culminated at the 32 mg/kg dose and became smaller for higher doses (64-128 mg/kg). When opposed to increasing dos
Publikováno v:
Synapse (New York, N.Y.). 21(1)
The long-term effects of a unique injection of reserpine (5 mg/kg s.c.) on the vesicular monoamine transporter and dopamine uptake complex have been investigated, in parallel with behavioral and neurochemical effects. Early after treatment, a dramati