Iowa gambling task impairment in Parkinson's disease can be normalised by reduction of dopaminergic medication after subthalamic stimulation

Autor: Paul Krack, Anna Castrioto, Roshan Cools, Aurélie Funkiewiez, Claire Ardouin, Trevor W. Robbins, Bettina Debû, Stephan Chabardes, Pierre Pollak, Valérie Fraix, Eugénie Lhommée

Publikováno v: Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 86, No 2 (2015) pp. 186-190
Journal of Neurology, Neurosurgery, and Psychiatry, 86, 186-90
Journal of Neurology, Neurosurgery, and Psychiatry, 86, 2, pp. 186-90

Item does not contain fulltext BACKGROUND: Impulse control disorders (ICD), including pathological gambling, are common in Parkinson's disease (PD) and tend to improve after subthalamic (STN) stimulation after a marked reduction of dopaminergic medic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f7eecabff4d4932351dbf41f60b393
https://hdl.handle.net/2066/153228

The treatment of early Parkinson's disease

Autor: Ad Hovestadt, Bastiaan R. Bloem, Teus van Laar, Annemarie M. M. Vlaar

Publikováno v: Practical Neurology. 11(3):145-152

Many clinicians regard levodopa as a last resort in the symptomatic treatment of Parkinson's disease. Here we critically review the arguments that are typically used to postpone the start of levodopa for as long as possible. We will point out that mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391e98a063452938d1883d093c3fb062
https://hdl.handle.net/11370/caf4e935-030f-4567-b562-966b492d9841

GDNF-Secreting Human Neural Progenitor Cells Increase Tyrosine Hydroxylase and VMAT2 Expression in MPTP-Treated Cynomolgus Monkeys

Autor: Masatoshi Suzuki, Clive N. Svendsen, Jeffrey M. Moirano, Allison D. Ebert, Ben Roitberg, Sun Peng, Marina E. Emborg, Elizabeth E. Capowski, Valerie Joers, Patrick Aebischer

Publikováno v: Scopus-Elsevier
Cell Transplantation, Vol 17 (2008)

Human neural progenitor cells (hNPCs) have been proposed as a potential source of cells for ex vivo gene therapy. In this pilot study, three 5-year-old female cynomolgus monkeys received a single intracarotid infusion of MPTP, followed 1 week later b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a435e98d73f1c79bc7b94813e60d8235
https://doi.org/10.3727/096368908784423300

Amantadine reduces levodopa-induced dyskinesias in parkinsonian monkeys

Autor: P J Blanchet, Thomas N. Chase, Spyridon Konitsiotis

The antidyskinetic potential of the glutamate NMDA receptor channel blocker amantadine was evaluated in four levodopa-primed parkinsonian monkeys using two different regimens (1.25 or 2.5 mg/kg administered subcutaneously twice daily for 3-6 days). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b7a1d54e8c58c00b88df6f3b2e1f0d
http://olympias.lib.uoi.gr/jspui/handle/123456789/23946

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