Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Doo-Sup Choi"'
Autor:
Matthew Baker, Seungwoo Kang, Sa-Ik Hong, Minryung Song, Minsu Abel Yang, Lee Peyton, Hesham Essa, Sang Wan Lee, Doo-Sup Choi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The external globus pallidus (GPe) coordinates action-selection through GABAergic projections throughout the basal ganglia. GPe arkypallidal (arky) neurons project exclusively to the dorsal striatum, which regulates goal-directed and habitua
Externí odkaz:
https://doaj.org/article/ffce399bf5604da597db21576476263f
Publikováno v:
Cells, Vol 13, Iss 4, p 318 (2024)
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system (CNS). Most GABAergic neurons synthesize GABA from glutamate and release it in the synaptic cleft in the CNS. However, astrocytes can also synthesiz
Externí odkaz:
https://doaj.org/article/c100a2be20ea446f81ee161544eb6159
Autor:
Ryan T. Hurt, MD, PhD, Ivana T. Croghan, PhD, Darrell R. Schroeder, MS, Doo-Sup Choi, PhD, Karen Fischer, MA, Shawn Fokken, CCRP, Jon O. Ebbert, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 5, Pp 465-474 (2022)
Objective: To evaluate the safety and effectiveness of combination varenicline with lorcaserin in preventing post-cessation weight gain. Participants and Methods: We conducted a randomized (varenicline for 12 weeks + lorcaserin for 24 weeks vs vareni
Externí odkaz:
https://doaj.org/article/7368643706dc49e6b5d71b7cd8c29ce4
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/2910c0f8cf03495bb18140feaa7d76c9
Autor:
Pei Shang, Ada Man-Choi Ho, Maximilian Tufvesson-Alm, Daniel R. Lindberg, Caroline W. Grant, Funda Orhan, Feride Eren, Maria Bhat, Göran Engberg, Lilly Schwieler, Helena Fatouros-Bergman, Sophie Imbeault, Ryan M. Iverson, Surendra Dasari, Fredrik Piehl, Simon Cervenka, Carl M. Sellgren, Sophie Erhardt, Doo-Sup Choi
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Psychotic disorders are currently diagnosed by examining the patient’s mental state and medical history. Identifying reliable diagnostic, monitoring, predictive, or prognostic biomarkers would be useful in clinical settings and help to und
Externí odkaz:
https://doaj.org/article/82598aac70f147618f5d0f2b25a19fd1
Publikováno v:
Journal of Movement Disorders, Vol 14, Iss 3, Pp 193-203 (2021)
Parkinson’s disease (PD) is a severe neurodegenerative disease characterized by classic motor features associated with the loss of dopaminergic neurons and appearance of Lewy bodies in the substantia nigra. Due to the complexity of PD, a definitive
Externí odkaz:
https://doaj.org/article/cccf313f0fdb4c01a22f2710b01b8877
Autor:
Ming-Fen Ho, Cheng Zhang, Irene Moon, Lixuan Wei, Brandon Coombes, Joanna Biernacka, Michelle Skime, Doo-Sup Choi, Mark Frye, Kristen Schmidt, Kate Gliske, Jacqueline Braughton, Quyen Ngo, Cedric Skillon, Marvin Seppala, Tyler Oesterle, Victor Karpyak, Hu Li, Richard Weinshilboum
Publikováno v:
Molecular Metabolism, Vol 63, Iss , Pp 101534- (2022)
Objective: Alcohol consumption can increase circulating levels of fibroblast growth factor 21 (FGF21). The effects of FGF21 in the central nervous system are associated with the regulation of catecholamines, neurotransmitters that play a crucial role
Externí odkaz:
https://doaj.org/article/773404cfeb5949afa54547b081408c05
Autor:
Ming-Fen Ho, Cheng Zhang, Irene Moon, Brandon J. Coombes, Joanna Biernacka, Michelle Skime, Doo-Sup Choi, Paul E. Croarkin, Mark A. Frye, Quyen Ngo, Cedric Skillon, Tyler S. Oesterle, Victor M. Karpyak, Hu Li, Richard M. Weinshilboum
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acamprosate is an anti-craving drug used in alcohol use disorder (AUD) pharmacotherapy. However, only a subset of patients achieves optimal treatment outcomes. The identification of predictive biomarkers of acamprosate treatment response in patients
Externí odkaz:
https://doaj.org/article/445a37043746454796c7800fa3f24d90
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2022)
Mitochondria are essential organelles central to various cellular functions such as energy production, metabolic pathways, signaling transduction, lipid biogenesis, and apoptosis. In the central nervous system, neurons depend on mitochondria for ener
Externí odkaz:
https://doaj.org/article/3830ad6cf0ac4fd2bdd3740252839923
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-10 (2020)
Abstract Psychiatric disorders are a prevalent global health problem, over 900 million individuals affected by a continuum of mental and substance use disorders. Due to this high prevalence, and the substantial direct and indirect societal costs, it
Externí odkaz:
https://doaj.org/article/5a85beb870ce4c819b9f42afab4c969a