Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Donovan Drouillard"'
Autor:
Mahmoud AbuEid, Donna M. McAllister, Laura McOlash, Megan Cleland Harwig, Gang Cheng, Donovan Drouillard, Kathleen A. Boyle, Micael Hardy, Jacek Zielonka, Bryon D. Johnson, R. Blake Hill, Balaraman Kalyanaraman, Michael B. Dwinell
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102653- (2021)
Summary: Metabolic heterogeneity within the tumor microenvironment promotes cancer cell growth and immune suppression. We determined the impact of mitochondria-targeted complex I inhibitors (Mito-CI) in melanoma. Mito-CI decreased mitochondria comple
Externí odkaz:
https://doaj.org/article/3630e5359dc747fea35d724c0b59cc72
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C167-C182
Chemokines are chemotactic cytokines whose canonical functions govern movement of receptor-expressing cells along chemical gradients. Chemokines are a physiological system that is finely tuned by ligand and receptor expression, ligand or receptor oli
Autor:
Marina Pasca di Magliano, Benjamin L. Allen, David A. Tuveson, Jonathan B. Preall, Andrzej A. Dlugosz, Filip Bednar, Arvind Rao, Timothy L. Frankel, Costas A. Lyssiotis, Howard C. Crawford, Youngkyu Park, Michelle A. Anderson, Fatima Lima, Craig Johnson, Zeribe C. Nwosu, Eileen S. Carpenter, Kristee Brown, Megan T. Hoffman, Nicole E. Franks, Christopher J. Halbrook, Valerie Irizarry-Negron, Stephanie The, Ahmed Abbas, Carlos Espinoza, Christa Hansma, Abhishek Doshi, Ela Elyada, Erin Brosnan, Tobiloba E. Oni, Yuan Hao, LiJyun Syu, Donovan Drouillard, Yaqing Zhang, Samantha B. Kemp, Giulia Biffi, Nina G. Steele
SFigure1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4202dff8acf28066d138757d688c9778
https://doi.org/10.1158/1078-0432.22481249.v1
https://doi.org/10.1158/1078-0432.22481249.v1
Autor:
Marina Pasca di Magliano, Benjamin L. Allen, David A. Tuveson, Jonathan B. Preall, Andrzej A. Dlugosz, Filip Bednar, Arvind Rao, Timothy L. Frankel, Costas A. Lyssiotis, Howard C. Crawford, Youngkyu Park, Michelle A. Anderson, Fatima Lima, Craig Johnson, Zeribe C. Nwosu, Eileen S. Carpenter, Kristee Brown, Megan T. Hoffman, Nicole E. Franks, Christopher J. Halbrook, Valerie Irizarry-Negron, Stephanie The, Ahmed Abbas, Carlos Espinoza, Christa Hansma, Abhishek Doshi, Ela Elyada, Erin Brosnan, Tobiloba E. Oni, Yuan Hao, LiJyun Syu, Donovan Drouillard, Yaqing Zhang, Samantha B. Kemp, Giulia Biffi, Nina G. Steele
Supp Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2767641126ae9d72b82d2d86298191
https://doi.org/10.1158/1078-0432.22481231.v1
https://doi.org/10.1158/1078-0432.22481231.v1
Autor:
Marina Pasca di Magliano, Benjamin L. Allen, David A. Tuveson, Jonathan B. Preall, Andrzej A. Dlugosz, Filip Bednar, Arvind Rao, Timothy L. Frankel, Costas A. Lyssiotis, Howard C. Crawford, Youngkyu Park, Michelle A. Anderson, Fatima Lima, Craig Johnson, Zeribe C. Nwosu, Eileen S. Carpenter, Kristee Brown, Megan T. Hoffman, Nicole E. Franks, Christopher J. Halbrook, Valerie Irizarry-Negron, Stephanie The, Ahmed Abbas, Carlos Espinoza, Christa Hansma, Abhishek Doshi, Ela Elyada, Erin Brosnan, Tobiloba E. Oni, Yuan Hao, LiJyun Syu, Donovan Drouillard, Yaqing Zhang, Samantha B. Kemp, Giulia Biffi, Nina G. Steele
Purpose:Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0271f09c190e1dc142cd583a3dc6966
https://doi.org/10.1158/1078-0432.c.6530642.v1
https://doi.org/10.1158/1078-0432.c.6530642.v1
Publikováno v:
American journal of physiology. Cell physiology.
Chemokines are chemotactic cytokines whose canonical functions govern movement of receptor expressing cells along chemical gradients. Chemokines are a physiologic system that is finely tuned by ligand and receptor expression, ligand or receptor oligo
Autor:
Balaraman Kalyanaraman, Donna McAllister, Mahmoud AbuEid, Megan Cleland Harwig, Bryon D. Johnson, Michael B. Dwinell, Gang Cheng, Donovan Drouillard, Laura McOlash, Micael Hardy, Kathleen A. Boyle, R. Blake Hill, Jacek Zielonka
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102653-(2021)
iScience
iScience, 2021, 24 (6), pp.102653. ⟨10.1016/j.isci.2021.102653⟩
iScience
iScience, 2021, 24 (6), pp.102653. ⟨10.1016/j.isci.2021.102653⟩
Summary Metabolic heterogeneity within the tumor microenvironment promotes cancer cell growth and immune suppression. We determined the impact of mitochondria-targeted complex I inhibitors (Mito-CI) in melanoma. Mito-CI decreased mitochondria complex
Autor:
David A. Tuveson, Arvind Rao, Donovan Drouillard, Benjamin L. Allen, Yaqing Zhang, Ela Elyada, Howard C. Crawford, Zeribe C. Nwosu, Marina Pasca di Magliano, Andrzej A. Dlugosz, Erin Brosnan, Carlos Espinoza, Nicole E. Franks, Nina Steele, Costas A. Lyssiotis, Filip Bednar, Ahmed Abbas, Craig A. Johnson, Abhishek Doshi, Giulia Biffi, Timothy L. Frankel, Valerie Irizarry-Negron, Jonathan B. Preall, Fatima Lima, Samantha Kemp, Eileen S. Carpenter, Michelle A. Anderson, Tobiloba E. Oni, Christa Hansma, Christopher J. Halbrook, LiJyun Syu, Megan T. Hoffman, Kristee Brown, Yuan Hao, Young-Kyu Park
Publikováno v:
Clin Cancer Res
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 7
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 7
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this h
Autor:
Ethan V. Abel, Marina Pasca di Magliano, Shadae Schoettle, Donovan Drouillard, Howard C. Crawford, Nina Steele, Arthur Brannon
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Pancreatic cancer, one of the deadliest human malignancies, has a dismal 5-year survival rate of 9%. KRAS is the most commonly mutated gene in pancreatic cancer, but clinical agents that directly target mutant KRAS are not available. Several effector
Autor:
Nina G. Steele, Giulia Biffi, Samantha Kemp, Yaqing Zhang, Donovan Drouillard, LiJyun Syu, Yuan Hao, Tobiloba Oni, Erin Brosnan, Ela Elyada, Abhishek Doshi, Christa Hansma, Carlos Espinoza, Ahmed Abbas, Stephanie The, Valerie Irizarry-Negron, Christopher Halbrook, Nicole Franks, Megan Hoffman, Eileen Carpenter, Zeribe Nwosu, Youngkyu Park, Howard Crawford, Costas Lyssiotis, Timothy Frankel, Arvind Rao, Filip Bednar, Andrzej Dlugosz, Jonathan Preall, David Tuveson, Benjamin Allen, Marina Pasca di Magliano
Publikováno v:
Cancer Research. 81:117-117
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease characterized by an extensive fibroinflammatory stroma, which includes abundant cancer-associated fibroblast (CAF) populations. PDAC CAFs are heterogeneous, but the nature of this h