Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Donough Howard"'
Publikováno v:
Rheumatology. 60
Background/Aims Gastro-intestinal stromal tumour (GIST) is recognised as the most prevalent mesenchymal tumour of the gastro-intestinal (GI) tract. The vast majority of GIST display activating mutations in receptor tyrosine kinases, such as platelet-
Autor:
Mariko L. Ishimori, Lindsy J. Forbess, Raymond L. Stallings, Eamonn S. Molloy, Thilini Fernando, Joan Ní Gabhann, Jane Seo, Olga Piskareva, Siobhán Smith, Daniel J. Wallace, Swamy Venuturupalli, Pei Wen Wu, Richard Conway, Paul O'Connell, Phil Gallagher, Grainne Kearns, Eoghan M. McCarthy, Michael H. Weisman, Donough Howard, Caroline A. Jefferies
Publikováno v:
Journal of Autoimmunity. 79:105-111
Systemic lupus erythematosus (SLE) is a complex disease targeting multiple organs as a result of overactivation of the type I interferon (IFN) system, a feature currently being targeted by multiple biologic therapies against IFN-α. We have identifie
Autor:
Gaye Cunnane, Suzanne Donnelly, Michele F. Doran, Ruth Z Lee, Joan Ní Gabhann, Paul O'Connell, Caroline A. Jefferies, Grainne Kearns, Siobhán Smith, Donough Howard, Eoghan M. McCarthy
Publikováno v:
Rheumatology. 53:1586-1594
Objective The aim of this study was to explore the role of cytokines in the pathogenesis of SLE in a genetically homogeneous Caucasian SLE patient population. Methods Serum levels of the following cytokines were determined by ELISA in SLE patients (d
Autor:
Christina Doyle, Frank Doyle, Gaye Cunnane, Donough Howard, Ciara O’Loughlin, Barry J. Sheane
Publikováno v:
Clinical Rheumatology. 27:1029-1033
The visual analog scale (VAS) of pain is a ubiquitous clinical and research tool with widespread application in the rheumatic diseases. The objectives of this study were to assess if patients report pain differently to doctors or nurses, to determine
Autor:
Grainne Kearns, Eoghan M. McCarthy, Siobhán Smith, Donough Howard, Michele F. Doran, Gaye Cunnane, Ruth Z Lee, Joan Ní Gabhann, Caroline A. Jefferies, Paul O'Connell
Publikováno v:
Rheumatology (Oxford, England). 52(7)
Objective. The overall aim of this study is to identify clinical and serological features that are associated with B lymphocyte stimulator (BLyS) elevation in a homogeneous Caucasian SLE population and thereby identify patients who are most likely to
Autor:
Donough Howard, Paul F. Dellaripa
Publikováno v:
Nutrition and Rheumatic Disease ISBN: 9781588299765
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24e62f5625ab659b935f7da0c1b278e0
https://doi.org/10.1007/978-1-59745-403-2_13
https://doi.org/10.1007/978-1-59745-403-2_13
Autor:
Donough Howard, S. Donnelly, Eamonn S. Molloy, J. Ni Gabhann, Lorraine O'Neill, Caroline A. Jefferies, P. R. O'Connell, Eoghan M. McCarthy, Grainne Kearns, Siobhán Smith
Publikováno v:
Annals of the Rheumatic Diseases. 73:860.1-860
Background Systemic Lupus Erythematosus (SLE) involves complex interactions between the innate and adaptive immune systems. Monocytes are increasingly recognised to play a key role in the dysregulated immune response seen in SLE whilst more recently
Autor:
Eoghan M. McCarthy, Donough Howard, A.-B. Mongey, Rebecca Mahony, Caroline A. Jefferies, Siobhán Smith, Jennifer C. Byrne, Eamonn S. Molloy, J. Ni Gabhann, Grainne Kearns, P. R. O'Connell, S. Donnelly, Barbara M. Coffey, C. de Chaumont, Kevin Stacey
Publikováno v:
Annals of the Rheumatic Diseases. 72:A463.4-A464
Background Systemic Lupus Erythematosus(SLE) is characterised by complex interactions between both the innate and adaptive immune systems. Natural Killer(NK) cells and NK T cells(NKT) are increasingly recognised to play a significant role in the dysr
Autor:
Eoghan M. McCarthy, P. R. O'Connell, Donough Howard, J. Ni Gabhann, Caroline A. Jefferies, Grainne Kearns, Michele F. Doran, Ruth Z Lee, Siobhán Smith, Gaye Cunnane
Publikováno v:
Annals of the Rheumatic Diseases. 71:674.4-674
Background Elevated levels of B Lymphocyte Stimulator(BLyS) play an important role in the pathogenesis of Systemic Lupus Erythematosus. Although anti BLyS-targeted therapies have shown promise in the treatment of SLE, results of clinical trials highl
Publikováno v:
The Journal of Rheumatology. 36:1348.2-1349
To the Editor: A 55-year-old Caucasian man initially presented 6 years earlier to an outside facility with a photosensitive rash, arthritis, fatigue, and mild neutrophilia. He had a history of liver cirrhosis, felt to be secondary to previous alcohol