Zobrazeno 1 - 10
of 3 251
pro vyhledávání: '"Donor specific antibodies"'
Autor:
Ivana Dedinska, Andrej Ceres, Martina Schniederova, Karol Granak, Matej Vnucak, Monika Beliancinova, Patricia Kleinova, Timea Blichova, Milos Jesenak
Publikováno v:
Acta Medica Martiniana, Vol 24, Iss 2, Pp 55-65 (2024)
Calculated PRA testing in kidney transplantation has revolutionized the field by enabling a more accurate assessment of compatibility and risk prediction for AMR. On the other hand, The PIRCHE algorithm aims to identify the potentially immunogenic hu
Externí odkaz:
https://doaj.org/article/e5ab476253d04c6599b1b20f2c65c430
Publikováno v:
Transplantology, Vol 5, Iss 3, Pp 148-162 (2024)
The functional outcomes and restoration of form after vascularized composite allotransplantation (VCA) have exceeded the results that could be achieved with current autologous surgical techniques. However, the longevity of VCA grafts has been limited
Externí odkaz:
https://doaj.org/article/c5a305f11bc34c4794361a1f3228eb51
Autor:
Rohit Kapoor, Prashant Pandey, Amit Pande, Nivedita Dhingra, Lovy Gaur, Sugam Garg, Akriti Khare, Esha Kaul
Publikováno v:
Indian Journal of Transplantation, Vol 18, Iss 2, Pp 180-183 (2024)
The use of posttransplant cyclophosphamide has revolutionized the field of haploidentical hematopoietic stem cell transplant. The impact has been especially enhanced in low- and middle-income countries. Unrelated donor pool in developing nations is o
Externí odkaz:
https://doaj.org/article/f53b2da1e32a4f438966377ed74b1118
Autor:
Suzanne Bezstarosti, Pauline Erpicum, Gianni Maggipinto, Geertje J. Dreyer, Marlies E. J. Reinders, Soufian Meziyerh, Dave L. Roelen, Johan W. De Fijter, Jesper Kers, Laurent Weekers, Yves Beguin, François Jouret, Sebastiaan Heidt
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Mesenchymal stromal cells (MSCs) have immunomodulatory properties and are therefore considered promising tools in kidney transplantation. Although most studies have been conducted with autologous MSCs, using allogeneic MSCs as an off-the-shelf produc
Externí odkaz:
https://doaj.org/article/919d6ebe84cf49d689630a0b1463fa64
Autor:
Christopher Graham, Mark Litzow
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTIntroduction The likelihood of finding HLA-matched unrelated donors for rare HLA types and non-white European ancestry continues to be a challenge with less than a 70% chance of finding a full match. Mismatched transplants continue to have hi
Externí odkaz:
https://doaj.org/article/87a988b3f2654840adde5a420f289cf1
Autor:
Simona Sica, Elisabetta Metafuni, Filippo Frioni, Maria Assunta Limongiello, Eugenio Galli, Federica Sorà, Andrea Bacigalupo, Elvira Poggi, Mariano Antonio Feccia, Annarita Manfreda, Patrizia Chiusolo, Sabrina Giammarco
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionDonor-specific antibodies (DSAs) correspond to anti-HLA antibodies of the recipient that are specifically directed to a mismatched antigen of the donor. In the setting of solid organ transplantation DSAs are associated with rejection. The
Externí odkaz:
https://doaj.org/article/6e0c5f20bd0d4291a1a8c0ceea66515d
Autor:
Emmett Tsz Yeung Wong, Denise Pochinco, Anantharaman Vathsala, Wee Kun Koh, Amy Lim, Hersharan Kaur Sran, Matthew Ross D’Costa, Zi Yun Chang, Peter W. Nickerson, Chris Wiebe
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Eplet mismatch has been recognized as a more precise strategy for determining HLA compatibility by analyzing donor-recipient HLA differences at the molecular level. However, predicting post-transplant alloimmunity using single-molecule eplet mismatch
Externí odkaz:
https://doaj.org/article/beae58e73fce47238a9c46082ee2aee4
Autor:
Aylin Akifova, Klemens Budde, Michael Oellerich, Julia Beck, Kirsten Bornemann-Kolatzki, Ekkehard Schütz, Bilgin Osmanodja
Publikováno v:
Transplant International, Vol 37 (2024)
Antibody-mediated rejection (AMR) is a major cause of graft failure limiting long-term graft survival after kidney transplantation. Current diagnostic strategy to detect AMR is suboptimal and requires further improvement. Previously suggested treatme
Externí odkaz:
https://doaj.org/article/c5f5cdb1e10e4bbd8969ac1783f2fef8
Autor:
Douglas J. Norman, C. Kristian Enestvedt, Willscott E. Naugler, Rouella Erhan, Carley A. Shaut
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
IntroductionLiver transplant recipients may have pre-formed anti-HLA antibodies directed to mismatched HLA of the liver donor (donor specific antibodies, DSA) or not directed to the liver donor (non-donor specific, non-DSA). We observed the fate of t
Externí odkaz:
https://doaj.org/article/36b723b18c8d444a99c900ce14dc5986
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 59-61 (2024)
The main reason for graft loss is the rejection of the donor organ, which may occur at different time after transplantation and may be caused by the recipient’s organism reaction against donor’s human leukocyte antigen (HLA) proteins. Donor-speci
Externí odkaz:
https://doaj.org/article/fda7f4c531c8447aa4c4221e93a11d3b