Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Donny L.F. Chang"'
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151833 (2016)
PLoS ONE, Vol 11, Iss 3, p e0151833 (2016)
Purpose To determine whether hyperglycemic levels as determined from high hemoglobin A1c (HbA1c) levels influence intraocular pressure (IOP) in patients with non-proliferative diabetic retinopathy (NPDR). Methods A retrospective chart review was perf
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:E1452-E1456
Gestational hypothyroidism leads to adverse obstetric outcomes and intellectual impairment in offspring. Pregnancy thyroid screening is controversial.Our objective was to determine thyroid function testing and thyroid dysfunction rates in pregnant wo
Autor:
Angela M. Leung, Xuemei He, Lewis E. Braverman, Elizabeth N. Pearce, Sun Y. Lee, Donny L.F. Chang
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 25(5)
Iodinated contrast media (ICM) is a source of excess iodine that may induce thyroid dysfunction. A prospective cohort study was conducted to assess the effects of ICM on urinary iodine clearance and serum thyroid function tests (TFTs) in adults.In th
Publikováno v:
Molecular and Cellular Biology. 25:6154-6164
The p53-related p63 gene encodes six isoforms with differing N and C termini. TAp63 isoforms possess a transactivation domain at the N terminus and are able to transactivate a set of genes, including some targets downstream of p53. Accumulating evide
Autor:
Douglas B. Sawyer, Jay K. Amin, Mohit Jain, Franz R. Eberli, Wilson S. Colucci, Carl S. Apstein, Donny L.F. Chang, Soeun Ngoy, Flora Sam
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 279:H422-H428
We tested the hypothesis that left ventricular (LV) remodeling late after myocardial infarction (MI) is associated with myocyte apoptosis in myocardium remote from the infarcted area and is related temporally to LV dilation and contractile dysfunctio
Autor:
Krishna Singh, Wilson S. Colucci, David R. Pimental, Deborah A. Siwik, John D. Tzortzis, Patrick J. Pagano, Douglas B. Sawyer, Donny L.F. Chang
Publikováno v:
Circulation Research. 85:147-153
Abstract —Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested the hypothesis that inhibition of endogenous antioxidant enzymes can regulate the phenotype of cardiac myocytes. Neonatal rat ventricular myocyte
Autor:
Elizabeth N. Pearce, Donny L.F. Chang
Publikováno v:
Journal of Thyroid Research, Vol 2013 (2013)
Journal of Thyroid Research
Journal of Thyroid Research
Observational studies have demonstrated that maternal thyroid dysfunction and thyroid autoimmunity in pregnancy may be associated with adverse obstetric and fetal outcomes. Treatment of overt maternal hyperthyroidism and overt hypothyroidism clearly
Autor:
Elizabeth G. Demicco, Zhi-Xiong Jim Xiao, Gail E. Sonenshein, Haoqiang Ying, Nicolas Currier, Sandra E. Solomon, Robert D. Cardiff, Isabel Dominguez, Marganit Farago, David H. Sherr, Donny L.F. Chang, David C. Seldin
Publikováno v:
Toxicologic pathology. 33(6)
Only about 5% of human breast cancers can be attributed to inheritance of breast cancer susceptibility genes, while the balance are considered to be sporadic in origin. Breast cancer incidence varies with diet and other environmental influences, incl
Autor:
Hongwu Zheng, Haoqiang Ying, Patima Sdek, Wei Qiu, Martin J. Allday, Donny L.F. Chang, Robert Touitou, Zhi-Xiong Jim Xiao
Publikováno v:
Molecular cell. 20(5)
Inactivation of retinoblastoma protein (Rb) plays a critical role in the development of human malignancies. It has been shown that Rb is degraded through a proteasome-dependent pathway, yet the mechanism is largely unclear. MDM2 is frequently found a
Autor:
Soeun Ngoy, Wilson S. Colucci, Daniel A. Brenner, Zhonglin Xie, Krishna Singh, Deborah A. Siwik, Douglas B. Sawyer, Carl S. Apstein, Flora Sam, Donny L.F. Chang
Publikováno v:
Circulation research. 89(4)
Nitric oxide produced by inducible nitric oxide synthase (NOS2) has been implicated in the pathophysiology of chronic myocardial remodeling and failure. We tested the role of NOS2 in left ventricular (LV) remodeling early (1 month) and late (4 months