Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Donnie S. Bundman"'
Publikováno v:
Human Molecular Genetics. 14:1539-1547
Myotonic dystrophy type I (DM1) is an RNA-mediated disease caused by a non-coding CTG repeat expansion. A key feature of the RNA-mediated pathogenesis model for DM is the disrupted splicing of specific pre-mRNA targets. A link has been established be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cfd935b8438eef1894cc6e7c881edf
https://doi.org/10.1093/hmg/ddi162
https://doi.org/10.1093/hmg/ddi162
Autor:
Elisabeth Scharer, Michal Jarnik, Donnie S. Bundman, Dennis R. Roop, Pierre A. de Viragh, Alasdair C. Steven, Martha N. Simon
Publikováno v:
Journal of Investigative Dermatology. 118:102-109
The cornified cell envelope, a lipoprotein layer that assembles at the surface of terminally differentiated keratinocytes, is a resilient structure on account of covalent crosslinking of its constituent proteins, principally loricrin, which accounts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b45a0aa8162292d93533d43b6b29e2
https://doi.org/10.1046/j.0022-202x.2001.01661.x
https://doi.org/10.1046/j.0022-202x.2001.01661.x
Autor:
Dennis R. Roop, Mary A. Longley, Michal Jarnik, Yasushi Suga, Alasdair C. Steven, Donnie S. Bundman, Peter Koch, Paul S. Attar
Publikováno v:
Journal of Cell Biology. 151:401-412
Mutations in the cornified cell envelope protein loricrin have been reported recently in some patients with Vohwinkel syndrome (VS) and progressive symmetric erythrokeratoderma (PSEK). To establish a causative relationship between loricrin mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75dc2731c2d9da493764915a48b687c5
https://doi.org/10.1083/jcb.151.2.401
https://doi.org/10.1083/jcb.151.2.401
Autor:
Marcel Huber, Yasushi Suga, Dennis R. Roop, Mary A. Longley, Yasuhiro Kawachi, Daniel Hohl, Jackie R. Bickenbach, Tonja Kartasova, Pierre A. de Viragh, Michal Jarnik, Alasdair C. Steven, Donnie S. Bundman, Zhijian Zhou, Peter Koch, Elisabeth Scharer
Publikováno v:
Journal of Cell Biology. 151:389-400
The epidermal cornified cell envelope (CE) is a complex protein–lipid composite that replaces the plasma membrane of terminally differentiated keratinocytes. This lamellar structure is essential for the barrier function of the skin and has the abil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb87750080be6e3d6fa13f075da44e4
https://doi.org/10.1083/jcb.151.2.389
https://doi.org/10.1083/jcb.151.2.389
Autor:
Masashi Ogo, Donnie S. Bundman, Dennis R. Roop, Joseph A. Rothnagel, Toshihiko Seki, Jackie R. Bickenbach, Mary A. Longley, Sonja M. Wojcik
Publikováno v:
Differentiation. 65:119-130
Keratin 6 (K6) is expressed constitutively in a variety of internal stratified epithelia as well as in palmoplantar epidermis and in specialized cells of the hair follicle. K6 expression can also be induced by hyperproliferative conditions as in woun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5651450e8c6f850507c8a39b4ad6b3e9
https://doi.org/10.1046/j.1432-0436.1999.6520119.x
https://doi.org/10.1046/j.1432-0436.1999.6520119.x
Autor:
Dennis R. Roop, Savio L. C. Woo, David A. Greenhalgh, Ken-ichiro Kosai, Milton J. Finegold, Bernd Bonnekoh, Thomas Krieg, Donnie S. Bundman, Shu-Hsia Chen
Publikováno v:
Journal of Investigative Dermatology. 106:1163-1168
To assess the efficacy of an in vivo adenoviral-mediated cytotoxic gene therapy, human melanomas were established in nude mice and transduced with herpes simplex virus-thymidine kinase (tk) followed by treatment with ganciclovir (GCV). In initial exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f9b1e91074377f52bfc173c18c3127
https://doi.org/10.1111/1523-1747.ep12347786
https://doi.org/10.1111/1523-1747.ep12347786
Autor:
Donnie S. Bundman, Savio L. C. Woo, Dennis R. Roop, Shu-Hsia Chen, David A. Greenhalgh, Joshua N. Eckhardt, Bernd Bonnekoh, Mary A. Longley
Publikováno v:
Journal of Investigative Dermatology. 104(3):313-317
To assess the potential of an in vivo, adenovirus-mediated gene therapy approach for the treatment of malignant melanoma, the efficacy of adenovirus-mediated herpes simplex virus thymidine kinase gene (HSV-Ek) transfer and administration of ganciclov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a41c68511bffb965676c840e251632
Autor:
Sumihisa Imakado, Joseph A. Rothnagel, V R Walczak, P S Attar, Jackie R. Bickenbach, Joel S. Gordon, Xiaojing Wang, S Wisniewski, Donnie S. Bundman, J Pote
Publikováno v:
Genes & Development. 9:317-329
To study the effects of retinoic acid on the skin in vivo, we have subverted the activity of endogenous receptors by targeting expression of a dominant negative mutant of retinoic acid receptor alpha (RAR alpha) to the epidermis of transgenic mice. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a1bf85ce2aa0a80a9cb1d2f956e575
https://doi.org/10.1101/gad.9.3.317
https://doi.org/10.1101/gad.9.3.317
Autor:
Thomas Mehrel, Donnie S. Bundman, Christina Cheng, Alasdair C. Steven, Stuart H. Yuspa, Joseph A. Rothnagel, Peter M. Steinert, M. E. Bisher, Daniel Hohl, Ulrike Lichti, Mary A. Longley, Dennis R. Roop
Publikováno v:
Cell. 61:1103-1112
During epidermal cell cornification, the deposition of a layer of covalently cross-linked protein on the cytoplasmic face of the plasma membrane forms the cell envelope. We have isolated and characterized cDNA clones encoding a major differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81822510420a7c1c108875e2cd0a5f8
https://doi.org/10.1016/0092-8674(90)90073-n
https://doi.org/10.1016/0092-8674(90)90073-n
Publikováno v:
Nucleic Acids Research
Alternative splicing is the primary source of proteome complexity in metazoans and its regulation shapes the proteome in response to shifting physiological requirements. We developed a bichromatic splicing reporter that uses a peculiar feature of som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f95e5fb6c3cb54fac8f48a2b89e940
https://pubmed.ncbi.nlm.nih.gov/17142220
https://pubmed.ncbi.nlm.nih.gov/17142220