Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Donna Woulfe"'
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Cigarette smoking is one of the major causes of coronary heart disease with a thirty percent mortality rate in the United States. Cigarette smoking acting on the central nervous system (CNS) to stimulate the sympathetic nervous system (SNS) through,
Externí odkaz:
https://doaj.org/article/e24f7372e1e14a10a8c75b4529bc24de
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Introduction: Little is known about the role of P2Y12 oligomerization in receptor function and whether P2Y12 receptor mutations associated with human bleeding disorders may be explained by alterations in oligomerization. Objectives: 1) To determine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4772d5aaeb2e1205175aaefb3880db
https://doi.org/10.1161/atvb.35.suppl_1.599
https://doi.org/10.1161/atvb.35.suppl_1.599
Autor:
Debora K Mukaz, Ann-Desdemonia N Fowajuh, Dongjun Li, Jeff Caplan, Andrea Vortkamp, Donna Woulfe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Transmembrane (TMEM)16f is a protein from the family of TMEM16 Ca++-dependent Chloride channels that is essential for optimal Ca2+-dependent phospholipid scrambling activity in platelets. Recently, it has been shown that TMEM16f-dependent exposure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae78f8a20ee1850db3d5085bc4075c0
https://doi.org/10.1161/atvb.33.suppl_1.a8
https://doi.org/10.1161/atvb.33.suppl_1.a8
Publikováno v:
The Journal of clinical investigation. 113(3)
Prior studies have shown that PI3Ks play a necessary but incompletely defined role in platelet activation. One potential effector for PI3K is the serine/threonine kinase, Akt, whose contribution to platelet activation was explored here. Two isoforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3077b7c1a76dd6ea68cf79b32d27cf40
https://pubmed.ncbi.nlm.nih.gov/14755341
https://pubmed.ncbi.nlm.nih.gov/14755341
Autor:
Jing, Yang, Jie, Wu, Hong, Jiang, Richard, Mortensen, Sandra, Austin, David R, Manning, Donna, Woulfe, Lawrence F, Brass
Publikováno v:
The Journal of biological chemistry. 277(48)
Platelet responses at sites of vascular injury are regulated by intracellular cAMP levels, which rise rapidly when prostacyclin (PGI(2)) is released from endothelial cells. Platelet agonists such as ADP and epinephrine suppress PGI(2)-stimulated cAMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d0d4b239f881ead8a7a4c05413528ac
https://pubmed.ncbi.nlm.nih.gov/12297509
https://pubmed.ncbi.nlm.nih.gov/12297509