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pro vyhledávání: '"Donna Thibault Flesher"'
Publikováno v:
Expert Review of Clinical Immunology. 6:461-479
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the production of antinuclear autoantibodies and the inflammatory infiltration of many organ systems. SLE is a complex disorder in which multiple genetic variants, t
Autor:
Jihong Yang, Xiangdan Wang, Eric Wakshull, Alyssa Morimoto, Ann Brady, Alexander R. Abbas, Bruce Richardson, Michael J. Townsend, Valerie Quarmby, Kristen Wolslegel, Donna Thibault Flesher, Timothy W. Behrens
Publikováno v:
Arthritis and rheumatism. 63(8)
Numerous observations implicate interferon-α (IFNα) in the pathophysiology of systemic lupus erythematosus (SLE); however, the potential impact of endogenous anti-IFNα autoantibodies (AIAAs) on IFN-pathway and disease activity is unclear. The aim