Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Donna Shows"'
Publikováno v:
Inflammatory Bowel Diseases. 29:S80-S81
BACKGROUND Inflammatory bowel disease (IBD) causes T cell infiltration of the intestinal mucosa, but the heterogeneity of these cells is not understood at a clonal level. The drug vedolizumab is believed to treat IBD by blocking the entry of circulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed444c7bd29885b09ecfca3f779c4d7
https://doi.org/10.1093/ibd/izac247.154
https://doi.org/10.1093/ibd/izac247.154
Autor:
Virginia Muir, Sara Sagadiev, Shuozhi Liu, Ursula Holder, Andrea M. Armendariz, Emmaline Suchland, Iana Meitlis, Nathan Camp, Natalia Giltiay, Jenny M. Tam, Ethan C. Garner, Carl N. Wivagg, Donna Shows, Richard G. James, Adam Lacy-Hulbert, Mridu Acharya
Publikováno v:
Autophagy.
Macroautophagy/autophagy proteins have been linked with the development of immune-mediated diseases including lupus, but the mechanisms for this are unclear due to the complex roles of these proteins in multiple immune cell types. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ebe0c1d5175c04aad2ca7e8b60f0e5
https://pubmed.ncbi.nlm.nih.gov/36016494
https://pubmed.ncbi.nlm.nih.gov/36016494
Publikováno v:
Gastroenterology. 158:S-958
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9536d8c87ba14317125968bb716d3df1
https://doi.org/10.1016/s0016-5085(20)33073-0
https://doi.org/10.1016/s0016-5085(20)33073-0
Publikováno v:
Gastroenterology. 156:S-713
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9969ee290bd5f93218201e92e4e96e14
https://doi.org/10.1016/s0016-5085(19)38719-0
https://doi.org/10.1016/s0016-5085(19)38719-0
Autor:
Phil Morrissey, Donna Shows, Kim Waggie, Sabine S. Escobar, Lillian Maggio-Price, Weiping Zeng, Andrew Burich, Joanne L. Viney
Publikováno v:
The American Journal of Pathology. 160:739-751
mdr1a-deficient mice lack P-glycoprotein and spontaneously develop colitis with age. Helicobacter spp. are gram-negative organisms that have been associated with colitis in certain mouse strains, but Helicobacter spp. have been excluded as contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a437706f6acc9fc3f3b592a9b0af2630
https://doi.org/10.1016/s0002-9440(10)64894-8
https://doi.org/10.1016/s0002-9440(10)64894-8
Publikováno v:
Gastroenterology. 152:S999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b6969b89c00bb542c66b8b4569437e
https://doi.org/10.1016/s0016-5085(17)33386-3
https://doi.org/10.1016/s0016-5085(17)33386-3
Publikováno v:
Gastroenterology. 152:S39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca44863dd4b187665e3e5808e5c6775
https://doi.org/10.1016/s0016-5085(17)30493-6
https://doi.org/10.1016/s0016-5085(17)30493-6
Autor:
Jennifer L. Slack, Roy A. Black, Carl J. Kozlosky, Douglas P. Cerretti, Raymond J. Davis, Donna Shows, Rebecca A. Blanton, Pranhitha Reddy, Jacques J. Peschon
Publikováno v:
Journal of Biological Chemistry. 275:14608-14614
Many membrane-bound proteins, including cytokines, receptors, and growth factors, are proteolytically cleaved to release a soluble form of their extracellular domain. The tumor necrosis factor (TNF)-alpha converting enzyme (TACE/ADAM-17) is a transme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07ce1f25e9a5800a2ca0ef0179934ee
https://doi.org/10.1074/jbc.275.19.14608
https://doi.org/10.1074/jbc.275.19.14608
Publikováno v:
The Journal of Immunology. 196:54.9-54.9
Background Crohn’s disease (CD) may be an inappropriate immune reaction to normally well-tolerated intestinal bacterial antigens. Indeed, many CD patients possess abnormally high titers of antibodies specific for intestinal bacterial proteins, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a1fb7752794cba149af9e3840d3351c
https://doi.org/10.4049/jimmunol.196.supp.54.9
https://doi.org/10.4049/jimmunol.196.supp.54.9
Autor:
Narasimharao Bhagavathula, Hal Blumberg, Keith Bailey, John E. Sims, Donna Shows, Muhammad Aslam, James Varani, Jennifer E. Towne, Charles W. Dean, Huyen Dinh, Esther S. Trueblood
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(7)
Psoriasis is a common immune-mediated disease in European populations; it is characterized by inflammation and altered epidermal differentiation leading to redness and scaling. T cells are thought to be the main driver, but there is also evidence for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cb5d27cbf05868a62a501fd15c7794
https://pubmed.ncbi.nlm.nih.gov/20833839
https://pubmed.ncbi.nlm.nih.gov/20833839