Výsledky vyhledávání - "Donna Rakiewicz"

Discovery and Biological Activity of Orally Active Peptidyl Trifluoromethyl Ketone Inhibitors of Human Neutrophil Elastase

Autor: Diane Amy Trainor, Mark A. Zottola, Joseph C. Williams, Richard Alan Wildonger, Barbara Ewing, Wolanin Donald John, Russell C. Mauger, Chris A. Veale, Joseph James Lewis, Ann M. Strimpler, Donald W. Andisik, Tuthill Paul Anson, G. B. Steelman, Philip D. Edwards, Donna Rakiewicz, Bruce Gomes, Craig Bryant

Publikováno v: Journal of Medicinal Chemistry. 40:1876-1885

Previously we had shown that tripeptidyl trifluoromethyl ketones (TFMKs) possessing an N-terminal diarylacylsulfonamide, such as ICI 200,880 and ICI 200,355, displayed unparalleled protection against the lung damage induced by human neutrophil elasta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9693c01d8a433142f42ac0491b2b03d5
https://doi.org/10.1021/jm960819g

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