Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Donna Perry-Lalley"'
Autor:
Ken-ichi Hanada, James Chih-Hsin Yang, Donna Perry-Lalley, Hung T. Khong, Qiong J. Wang, Tatiana S. Karpova, Maria P. Bettinotti
Publikováno v:
Journal of Immunotherapy. 28:551-559
Summary: Dendritic cells (DCs) have been used as professional antigen-presenting cells in vitro to prime T-cell responses. In this study, we generated both CD8 + and CD4 + renal cell carcinoma (RCC)-reactive T cells using a completely autologous syst
High Avidity CTLs for Two Self-Antigens Demonstrate Superior In Vitro and In Vivo Antitumor Efficacy
Publikováno v:
The Journal of Immunology. 162:989-994
A majority of the human tumor-associated Ags characterized to date are derived from nonmutated “self”-proteins. Little is currently understood about the nature of the self-reactive lymphocytes that recognize these Ags. We recently characterized t
Autor:
Donna Perry-Lalley, Yong Li, Steven A. Rosenberg, James Chih-Hsin Yang, Paul F. Robbins, Mona El-Gamil, Matthew B. Bloom
Publikováno v:
The Journal of Experimental Medicine
Recently, major advances have been made in the identification of antigens from human melanoma which are recognized by T cells. In spite of this, little is known about the optimal ways to use these antigens to treat patients with cancer. Progress in t
Autor:
James Chih-Hsin Yang, Stuart G. Marcus, James J. Mulé, Donna Perry-Lalley, Steven A. Rosenberg
Publikováno v:
Journal of Immunotherapy. 15:105-112
Tumor-infiltrating lymphocytes (TIL) are cytotoxic T cells isolated from solid tumors and expanded in vitro in recombinant interleukin-2 (rIL-2). TIL have antitumor effects in murine models and in some patients with melanoma. In an effort to generate
Autor:
Gang Zeng, Nicholas P. Restifo, Rongfu Wang, Patrick Hwu, Tihui Fu, Helen Yicheng Wang, James Chih-Hsin Yang, Gang Wang, Donna Perry-Lalley
Dendritic cell-based (DC-based) immunotherapy represents a promising approach to the prevention and treatment of many diseases, including cancer, but current strategies have met with only limited success in clinical and preclinical studies. Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd7d696a9d2ea599107363d4a42f3d0
https://europepmc.org/articles/PMC151000/
https://europepmc.org/articles/PMC151000/
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 23(2)
Recently, significant progress has been made in identifying specific tumor-associated antigens recognized by T cells and defining the specific peptide epitopes within these proteins that are processed and presented on class I major histocompatibility
Publikováno v:
Cellular immunology. 120(2)
Sensitized T lymphocytes can mediate potent antitumor effects when transferred to tumor-bearing animals. Employing the MCA 105 and MCA 106 sarcomas, we were able to generate antitumor effector cells by immunization of syngeneic mice with tumor cells