Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Donna Parke"'
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Purpose Natural products represent a rich reservoir of potential small molecule inhibitors exhibiting antiproliferative and tumoricidal properties. An example is the isoquinoline alkaloid berberine, which is found in plants such as goldenseal (Hydras
Publikováno v:
Annual Review of Microbiology. 59:519-551
The genetic and physiological properties of Acinetobacter baylyi strain ADP1 make it an inviting subject for investigation of the properties underlying its nutritional versatility. The organism possesses a relatively small genome in which genes for m
Autor:
Donna Parke, L. Nicholas Ornston
Publikováno v:
Applied and Environmental Microbiology. 69:5398-5409
Hydroxycinnamates are plant products catabolized through the diphenol protocatechuate in the naturally transformable bacterium Acinetobacter sp. strain ADP1. Genes for protocatechuate catabolism are central to the dca-pca-qui-pob-hca chromosomal isla
Autor:
Donna Parke
Publikováno v:
Journal of Bacteriology. 182:6145-6153
A positive selection method for mutations affecting bioconversion of aromatic compounds was applied to a mutant strain of Agrobacterium tumefaciens A348. The nucleotide sequence of the A348 pcaHGB genes, which encode protocatechuate 3,4-dioxygenase (
Publikováno v:
Journal of Bacteriology. 182:257-263
Microorganisms in the environment encounter a varied and not invariably benign diet. The primary suppliers of nutrients for microorganisms are plants. Consumers such as fungi and bacteria do not act singly and often offer plants a return on their inv
Autor:
Donna Parke
Publikováno v:
FEMS Microbiology Letters. 146:3-12
Widely distributed among members of the Rhizobiaceae, the protocatechuate branch of the β-ketoadipate pathway is central to the catabolism of 4-hydroxybenzoate and certain other phenolic compounds. Genetic elements underlying 4-hydroxybenzoate dissi
Autor:
Sandro L. Pereira, Edward Perkins, Teresa L. Serafim, Jon M Holy, Paulo J. Oliveira, Gonçalo C. Pereira, Vilma A. Sardão, Antonio Moreno, Donna Parke, Ana F. Branco, Júlio A.C. Matos
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Sanguinarine (SANG) is an alkaloid recognized to have anti-proliferative activity against various human tumour cell lines. No data is available on the susceptibility of advanced malignant melanoma to SANG, although this disease has a very poor progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adef1a3cbee63fda7baa993d2632f4fd
Autor:
L. Nicholas Ornston, Donna Parke
Publikováno v:
Acinetobacter Biology and Pathogenesis ISBN: 9780387779430
Early investigations of Acinetobacter genetics focused upon Acinetobacter baylyi because the extraordinary competence of this species for natural transformation (Carr et al., 2003; Vaneechoutte et al., 2006) allowed convenient genetic analysis (Young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb424e60de554bbc6205d0f0f8351bcb
https://doi.org/10.1007/978-0-387-77944-7_3
https://doi.org/10.1007/978-0-387-77944-7_3
Autor:
Antonio Moreno, Júlio A.C. Matos, Jon M Holy, Edward Perkins, Donna Parke, Ana F. Branco, Teresa L. Serafim, Paulo J. Oliveira, Maria S. Santos, Sandro L. Pereira, Vilma A. Sardão, Gonçalo C. Pereira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium] is an alkaloid present in plant extracts and has a history of use in traditional Chinese and Native American medicine. Because of its ability to ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78fadca53456b4ede292ef0e069d6d3
Autor:
L. Nicholas Ornston, Donna Parke
Publikováno v:
Applied and environmental microbiology. 70(5)
Hydroxycinnamates, aromatic compounds that play diverse roles in plants, are dissimilated by enzymes encoded by the hca genes in the nutritionally versatile, naturally transformable bacterium Acinetobacter sp. strain ADP1. A key step in the hca -enco