Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Donna O. Bunch"'
Autor:
Vimal K. Derebail, Patrick H. Nachman, Elizabeth J. Brant, Donna O. Bunch, Susan L. Hogan, Matthew L. McDermott, Carmen E. Mendoza, Yichun Hu, J. Charles Jennette, Anne Froment, Ronald J. Falk
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 4, Iss 11, Pp 1617-1629 (2019)
Kidney International Reports, Vol 4, Iss 11, Pp 1617-1629 (2019)
Introduction: Venous thromboembolism (VTE) is a life-threatening complication of anti-neutrophil cytoplasmic autoantibody (ANCA) vasculitis whose mechanism remains incompletely elucidated. We tested the hypothesis that elevated microparticle tissue f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9909a3d6d3c1f1257d12d731d5d24385
https://pubmed.ncbi.nlm.nih.gov/31891003
https://pubmed.ncbi.nlm.nih.gov/31891003
Autor:
Patrick H. Nachman, J.L. Hillson, J. Deng, Pirow Bekker, T.J. Schall, Charles Jennette, Donna O. Bunch, Elizabeth A. McInnis
Publikováno v:
WEDNESDAY, 13 JUNE 2018.
Immunobiology of vasculitis Background The interaction between primed neutrophils and anti-neutrophil cytoplasmic autoantibodies (ANCA) releases factors that activate the alternative complement pathway, initiating an amplification loop that is though
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcd84e6faff688d368763574e5ac4157
https://doi.org/10.1136/annrheumdis-2018-eular.6032
https://doi.org/10.1136/annrheumdis-2018-eular.6032
Autor:
E. Christiaan Hagen, Arda Göçeroğlu, Donna O. Bunch, Elsa Grenmyr, Yngve Sommarin, Annelies E. Berden, Ingeborg M. Bajema, Jörgen Wieslander, Jan A. Bruijn
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207064 (2018)
PLoS ONE
PLoS ONE
Anti-plasminogen antibodies (α-PLG) were previously detected in a subpopulation of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients, showing a relation to renal lesions and outcome. Several studies showed different pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cb4d9d6233c463683d60b84f14f0cc
http://europepmc.org/articles/PMC6231631?pdf=render
http://europepmc.org/articles/PMC6231631?pdf=render
Autor:
Aleeza J. Roth, Barrak M. Pressler, Gloria A. Preston, H. Terence Cook, J. Charles Jennette, Elizabeth A. Alderman, John Reynolds, Michael C. Brown, Ronald J. Falk, Donna O. Bunch, Peter Hewins, Charles D. Pusey
Publikováno v:
Journal of Autoimmunity. 59:8-18
'Autoantigen complementarity' is a theory proposing that the initiator of an autoimmune response is not necessarily the autoantigen or its molecular mimic, but may instead be a peptide that is 'antisense/complementary' to the autoantigen. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b352099f0fa18ebcb2cb2011d06f5e
https://doi.org/10.1016/j.jaut.2015.01.003
https://doi.org/10.1016/j.jaut.2015.01.003
Autor:
Meghan E. Free, Britta E. Jones, Ronald J. Falk, Yichun Hu, Donna O. Bunch, Gloria A. Preston, J. Charles Jennette, Julie Anne G. McGregor, Susan L. Hogan, Maureen A. Su, Elisabeth A. Berg
Publikováno v:
Arthritis & Rheumatism. 65:1922-1933
Objective The development of pathogenic antineutrophil cytoplasmic antibodies (ANCAs) can result in systemic small vessel vasculitis. However, the breakdown in immune tolerance that results in the induction and persistence of ANCAs is not well unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b60f698a322f0d22c1395131c5005df0
https://doi.org/10.1002/art.37959
https://doi.org/10.1002/art.37959
Autor:
Roberto Negrete-López, Julie Anne G. McGregor, Patrick H. Nachman, Yichun Hu, Donna O. Bunch, Elizabeth S. Kotzen, Jason M. Kidd, Suzanne L. Katsanos, Caroline J. Poulton, Susan L. Hogan, Ronald J. Falk
Rituximab has been used in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) since 2003. Our objective was to describe outcomes and adverse events following rituximab since that time in an inception cohort.Patients with AAV (diag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1487fe88ff34804e91cee9f0e816c312
https://europepmc.org/articles/PMC4447867/
https://europepmc.org/articles/PMC4447867/
Autor:
Sally D. Perreault, Deborah A. O'Brien, Edward M. Eddy, Eugenia H. Goulding, William D. Willis, Donna O. Bunch, Kiyoshi Miki, Lillian F. Strader, Weidong Qu
Publikováno v:
Proceedings of the National Academy of Sciences. 101:16501-16506
Although glycolysis is highly conserved, it is remarkable that several unique isozymes in this central metabolic pathway are found in mammalian sperm. Glyceraldehyde 3-phosphate dehydrogenase-S (GAPDS) is the product of a mouse gene expressed only du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c002c4f8c75c49dea2ee2e64bd842d
https://doi.org/10.1073/pnas.0407708101
https://doi.org/10.1073/pnas.0407708101
Autor:
Julie Anne G. McGregor, Yichun Hu, Lydia T. Aybar, Ronald J. Falk, Caroline J. Poulton, Carmen E. Mendoza, Susan L. Hogan, Elizabeth J. Brant, Candace D. Henderson, Donna O. Bunch
Publikováno v:
Clinical and experimental immunology. 180(2)
Summary Pathogenesis of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis is B cell-dependent, although how particular B cell subsets modulate immunopathogenesis remains unknown. Although their phenotype remains controversial, reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8775ccd7f83045919d02e416d01d9f4e
https://pubmed.ncbi.nlm.nih.gov/25376552
https://pubmed.ncbi.nlm.nih.gov/25376552
Autor:
J. Mcgregor, Patrick H. Nachman, William F. Pendergraft, Yichun Hu, Kerry R Colby, Lydia T. Aybar, Carmen E. Mendoza, John L. Schmitz, Caroline J. Poulton, Elizabeth S. Kotzen, Susan L. Hogan, Ronald J. Falk, Donna O. Bunch
Publikováno v:
Annals of the rheumatic diseases. 74(9)
B cell depletion is an effective remission induction and maintenance therapy in patients with antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV).1–6 Rituximab targets both pathogenic effector B cells and protective regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2752a97e5b12950d76787ccef6242811
https://pubmed.ncbi.nlm.nih.gov/25934841
https://pubmed.ncbi.nlm.nih.gov/25934841
Autor:
Patricia L. Magyar, Deborah A. O'Brien, Edward M. Eddy, Donna O. Bunch, Chisato Mori, Paula L. Brown, Jeffrey E. Welch
Publikováno v:
Journal of Andrology. 21:328-338
Although the process of glycolysis is highly conserved in eukaryotes, several glycolytic enzymes have unique structural or functional features in spermatogenic cells. We previously identified and characterized the mouse complementary DNA (cDNA) and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07f2c21beb6b4ad0e4417550b1e7b175
https://doi.org/10.1002/j.1939-4640.2000.tb02111.x
https://doi.org/10.1002/j.1939-4640.2000.tb02111.x