Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Donna M. Klinge"'
Autor:
Sandra J. Lee, Maria A. Picchi, Steven A. Belinsky, Jill M. Siegfried, Fadlo R. Khuri, Suresh S. Ramalingam, Seena C. Aisner, Cynthia L. Thomas, Daniel D. Karp, Shuguang Leng, Elia Casas, Guodong Wu, Donna M. Klinge, Christine A. Stidley
Publikováno v:
Oncotarget
// Shuguang Leng 1 , Guodong Wu 1 , Donna M. Klinge 1 , Cynthia L. Thomas 1 , Elia Casas 1 , Maria A. Picchi 1 , Christine A. Stidley 2 , Sandra J. Lee 3 , Seena Aisner 4 , Jill M. Siegfried 5 , Suresh Ramalingam 6 , Fadlo R. Khuri 6 , Daniel D. Karp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12b727766a2d0f24a2c7fb199d932b0
http://europepmc.org/articles/PMC5609978
http://europepmc.org/articles/PMC5609978
Autor:
Maria A. Picchi, Steven A. Belinsky, Amanda M. Snider, Christin M. Yingling, Donna M. Klinge, Yushi Liu, Carmen S. Tellez, Ivo Teneng
Publikováno v:
Oncogene. 34:621-630
The maintenance cytosine DNA methyltransferase DNMT1 and de novo methyltransferase DNMT3b cooperate to establish aberrant DNA methylation and chromatin complexes to repress gene transcription during cancer development. The expression of DNMT3b was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8110fb04b2febe664c467752360e3d8
https://doi.org/10.1038/onc.2013.580
https://doi.org/10.1038/onc.2013.580
Autor:
Amanda M. Bernauer, Cynthia L. Thomas, Jill M. Siegfried, Mathewos Tessema, Steven A. Belinsky, Yushi Liu, Joan H. Schiller, Donna M. Klinge, Suzanne E. Dahlberg, Sanja Dacic, Christin M. Yingling
Publikováno v:
Oncogene
The heparan sulfate 6-O-endosulfatase (SULF2) promotes growth and metastasis of solid tumors. We recently identified that cytosine methylation of the SULF2 promoter is associated with better survival of resected lung adenocarcinoma patients, and now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa5cdc00ac2a8f26d5ac30ea2190e02
https://doi.org/10.1038/onc.2011.577
https://doi.org/10.1038/onc.2011.577
Autor:
L. Van Neste, Christin M. Yingling, Steven A. Belinsky, Kieu Do, Donna M. Klinge, Mathewos Tessema
Publikováno v:
Oncogene
Chemokines are important regulators of directional cell migration and tumor metastasis. A genome-wide transcriptome array designed to uncover novel genes silenced by methylation in lung cancer identified the CXC-subfamily of chemokines. Expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18e85035cb3a77a757f251243a7e669
http://europepmc.org/articles/PMC2940978
http://europepmc.org/articles/PMC2940978
Autor:
Steven A. Belinsky, Thomas H. March, Leah A. Damiani, Donna M. Klinge, Marcie J. Grimes, Christine A. Stidley, Cindy L. Thomas, Christopher M. Lyon, Kieu Do
Publikováno v:
Carcinogenesis. 30:2095-2099
There is a critical need to identify efficacious chemopreventive agents for lung cancer that can be taken chronically with no side effects and whose mechanisms of action do not involve genotoxicity that could drive, rather than impede, cancer progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada0962f9ffeb20a2ee1902e78b02924
https://doi.org/10.1093/carcin/bgp260
https://doi.org/10.1093/carcin/bgp260
Autor:
Frank D. Gilliland, Frederick D. Gentry, Thomas H. March, Donna M. Klinge, Terri Kang, Christopher M. Lyon, Galina Adamova, Steven A. Belinsky, Vitaliy Telnov, G. G. Rusinova, Kieu C. Liechty
Publikováno v:
Radiation Research. 168:409-414
Epigenetic inactivation of genes by promoter hypermethylation, a major mechanism in the initiation and progression of tobacco-induced cancer, has also been associated with lung cancer induced through environmental and occupational exposures. Our prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8759c9b3124a596b463f4ea361f3699e
https://doi.org/10.1667/rr0825.1
https://doi.org/10.1667/rr0825.1
Autor:
G. G. Rusinova, Kieu C. Liechty, Donna M. Klinge, Steven A. Belinsky, Vitaliy Telnov, Natalie Sotnic, Frank D. Gilliland, Terri Kang, Galina Adamova, Thomas H. March
Publikováno v:
Carcinogenesis. 25:1063-1067
Lung cancer from radon or (239)plutonium exposure has been linked to alpha-particles that damage DNA through large deletions and point mutations. We investigated the involvement of an epigenetic mechanism, gene inactivation by promoter hypermethylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e83eb353fc81f6b7fb6004c85ed1b5f
https://doi.org/10.1093/carcin/bgh096
https://doi.org/10.1093/carcin/bgh096
Autor:
Steven A. Belinsky, Donna M. Klinge, Christine A. Stidley, Maria A. Picchi, Frank D. Gilliland, Joseph D. Dekker, Mitzi W. Smith, Daniel D. Karp, Theresa J. Bocklage, Richard E. Crowell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(18)
Purpose: Lung cancer is the leading cause of cancer mortality in the United States, due in part to the lack of a validated and effective screening approach for early detection. The prevalence for methylation of seven and three genes was examined in D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ce545c35c370c873c49dbd6cb1184d
https://pubmed.ncbi.nlm.nih.gov/16166426
https://pubmed.ncbi.nlm.nih.gov/16166426
Autor:
Leah C, Pulling, Kevin K, Divine, Donna M, Klinge, Frank D, Gilliland, Terri, Kang, Ann G, Schwartz, Therese J, Bocklage, Steven A, Belinsky
Publikováno v:
Cancer research. 63(16)
Adenocarcinoma (AC) is the most common type of lung cancer diagnosed in the United States, comprising up to 40% of tumors in smokers and 50-80% of tumors in never-smokers. Exposures to cigarette smoke, direct or second-hand, and radiation in the form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83dbba6bae49a18557416fb2a3a2b961
https://pubmed.ncbi.nlm.nih.gov/12941804
https://pubmed.ncbi.nlm.nih.gov/12941804
Publikováno v:
Carcinogenesis. 22(3)
Inactivation of the p16INK4a (p16) tumor suppressor gene by promoter hypermethylation and mutation within exon 3 of beta-catenin represent two of the more common gene alterations in human hepatocellular carcinoma (HCC). One exposure implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9cf000ebb885746daee8229a55f5ad
https://pubmed.ncbi.nlm.nih.gov/11238187
https://pubmed.ncbi.nlm.nih.gov/11238187