Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Donna M. Crabtree"'
Autor:
Herminio Joey Cardona, Agila Somasundaram, Donna M. Crabtree, Samantha L. Gadd, Oren J. Becher
Publikováno v:
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background Platelet‐derived growth factor (PDGF) signaling, through the ligand PDGF‐A and its receptor PDGFRA, is important for the growth and maintenance of oligodendrocyte progenitor cells (OPCs) in the central nervous system (CNS). PD
Externí odkaz:
https://doaj.org/article/018eac006c394b2d8961a27f7ac17d3a
Autor:
Zachary J. Reitman, Lixia Luo, Joshua S. Mercer, Yan Ma, Katherine Deland, Nerissa Williams, David G. Kirsch, Oren J. Becher, Donna M. Crabtree, Lorraine Da Silva Campos, M. Reinsvold, Maria E. Guerra Garcia
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Diffuse intrinsic pontine gliomas (DIPGs) arise in the pons and are the leading cause of death from brain tumors in children. DIPGs are routinely treated with radiation therapy, which temporarily improves neurological symptoms but generally f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f881d5f751b5f26b2328cdf6cab9b0c4
https://europepmc.org/articles/PMC8898173/
https://europepmc.org/articles/PMC8898173/
Autor:
Jacob L Mercer, Joseph P Argus, Donna M Crabtree, Melissa M Keenan, Moses Q Wilks, Jen-Tsan Ashley Chi, Steven J Bensinger, Catherine P Lavau, Daniel S Wechsler
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129776 (2015)
PICALM (Phosphatidyl Inositol Clathrin Assembly Lymphoid Myeloid protein) is a ubiquitously expressed protein that plays a role in clathrin-mediated endocytosis. PICALM also affects the internalization and trafficking of SNAREs and modulates macroaut
Externí odkaz:
https://doaj.org/article/b5ab8f45fcaa4981b52c1c2f7f6d7fb8
Autor:
Kyle G Halvorson, Kelly L Barton, Kristin Schroeder, Katherine L Misuraca, Christine Hoeman, Alex Chung, Donna M Crabtree, Francisco J Cordero, Raj Singh, Ivan Spasojevic, Noah Berlow, Ranadip Pal, Oren J Becher
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118926 (2015)
Diffuse intrinsic pontine gliomas (DIPGs) represent a particularly lethal type of pediatric brain cancer with no effective therapeutic options. Our laboratory has previously reported the development of genetically engineered DIPG mouse models using t
Externí odkaz:
https://doaj.org/article/f07c2cd8a85e4299b0ca697f85d8e523
Publikováno v:
Brain and Behavior
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Background Platelet‐derived growth factor (PDGF) signaling, through the ligand PDGF‐A and its receptor PDGFRA, is important for the growth and maintenance of oligodendrocyte progenitor cells (OPCs) in the central nervous system (CNS). PDGFRA sign
Autor:
Heather E. Whitson, Carl F. Pieper, Kenneth E. Schmader, Micah T. McClain, Denise Orwig, Cathleen S. Colón-Emeric, Jay Magaziner, Donna M. Crabtree, Richard Sloane, Allison Bloom, Kim M. Huffman
Publikováno v:
J Gerontol A Biol Sci Med Sci
Background Approaches for quantifying physical resilience in older adults have not been described. Methods We apply two conceptual approaches to defining physical resilience to existing longitudinal data sets in which outcomes are measured after an a
Autor:
Donna M. Crabtree, Katherine Deland, Yan Ma, Nerissa Williams, David G. Kirsch, Oren J. Becher, Jovita Byemerwa, Lixia Luo, Bryce F. Starr, Joshua S. Mercer, Mark Chen
Publikováno v:
J Clin Invest
Diffuse intrinsic pontine glioma (DIPG) kills more children than any other type of brain tumor. Despite clinical trials testing many chemotherapeutic agents, palliative radiotherapy remains the standard treatment. Here, we utilized Cre/loxP technolog
Autor:
Katherine Deland, Bryce F. Starr, Jovita Byemerwa, Yan Ma, Joshua S. Mercer, Donna M. Crabtree, Lixia Luo, Nerissa Williams, David G. Kirsch, Oren J. Becher, Mark Chen
Diffuse intrinsic pontine glioma (DIPG) kills more children than any other type of brain tumor. Despite clinical trials testing many chemotherapeutic agents, radiotherapy remains the standard treatment. Here, we utilized Cre/loxP technology to show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6734eac1bcbce1953cdd4530c852ae3
https://doi.org/10.1101/2020.08.24.262642
https://doi.org/10.1101/2020.08.24.262642
Autor:
Mark E. Easley, Marty G. Woldorff, John Whittle, Frank W. Rockhold, Oke A. Anakwenze, Jeffrey N. Browndyke, Daniel T. Laskowitz, Miles Berger, Keith W. VanDusen, Sarada S Eleswarpu, Michael J. Devinney, Michael P. Bolognesi, Donna M. Crabtree, William A. Jiranek, Mary Cooter, Marble Study Investigators, Kenneth C. Roberts, Eugene W. Moretti, Michael N. Ferrandino
Publikováno v:
J Alzheimers Dis
BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is