Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Donna M. Baldisseri"'
Autor:
Zacharie A. Maw, Bradley Haltli, Jason J. Guo, Donna M. Baldisseri, Christopher Cartmell, Russell G. Kerr
Publikováno v:
Molecules, Vol 29, Iss 7, p 1482 (2024)
We report the discovery of a novel cyclic nonribosomal peptide (NRP), acyl-surugamide A2, from a marine-derived Streptomyces albidoflavus RKJM-0023 (CP133227). The structure of acyl-surugamide A2 was elucidated using a combination of NMR spectroscopy
Externí odkaz:
https://doaj.org/article/20a47b56012e4a0383a122c2990d4d27
Autor:
Mark W. Peczuh, Trevor A. Hamlin, Kelli M. Rutledge, Donna M. Baldisseri, F. Matthias Bickelhaupt
Publikováno v:
Chemistry-An Asian Journal, 12(19), 2623-2633. John Wiley and Sons Ltd
Chemistry, an Asian Journal, 12, 2623-2633
Chemistry, an Asian Journal, 12, 19, pp. 2623-2633
Rutledge, K M, Hamlin, T A, Baldisseri, D M, Bickelhaupt, F M & Peczuh, M W 2017, ' Macrocycles All Aflutter : Substitution at an Allylic Center Reveals the Conformational Dynamics of [13]-Macrodilactones ', Chemistry-An Asian Journal, vol. 12, no. 19, pp. 2623-2633 . https://doi.org/10.1002/asia.201700997
Chemistry, an Asian Journal, 12, 2623-2633
Chemistry, an Asian Journal, 12, 19, pp. 2623-2633
Rutledge, K M, Hamlin, T A, Baldisseri, D M, Bickelhaupt, F M & Peczuh, M W 2017, ' Macrocycles All Aflutter : Substitution at an Allylic Center Reveals the Conformational Dynamics of [13]-Macrodilactones ', Chemistry-An Asian Journal, vol. 12, no. 19, pp. 2623-2633 . https://doi.org/10.1002/asia.201700997
The shapes adopted by large-ring macrocyclic compounds play a role in their reactivity and their ability to be bound by biomolecules. We investigated the synthesis, conformational analysis, and properties of a specific family of [13]-macrodilactones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca0f8f0f2ad9de4bee86fb4f98b0e7f
https://doi.org/10.1002/asia.201700997
https://doi.org/10.1002/asia.201700997
Autor:
Peter Schmieder, Ryan M. Evans, Robert G. Brinson, Chad W. Lawrence, Kristian Schweimer, Yves Aubin, Ping Xu, Göran Widmalm, Andreas Blomgren, Hamish G. Grant, Anthony J. Kearsley, John P. Marino, Janez Plavec, John B. Jordan, Geneviève Gingras, Scott A. Bradley, Koichi Kato, Stuart Parnham, Patrick N. Reardon, John R. Cort, David W. Keizer, Edward R. Zartler, Feng Ni, Frank Delaglio, Gregor Ilc, Saeko Yanaka, David A. Keire, Jonas Ståhle, Mats Wikström, Luke W. Arbogast, Alfred Ross, Thea Suter-Stahel, Darón I. Freedberg, Ana Carolina de Mattos Zeri, Maurício L. Sforça, Nils Trieloff, Desiree Tsao, Torgny Rundlöf, Xinying Jia, Kang Chen, Ken Skidmore, Gregory K. Pierens, Houman Ghasriani, Donna M. Baldisseri, Carlos A. Amezcua, Mehdi Mobli, Julie Yu Wei, Christina M. Szabo, Gerhard Wider
Publikováno v:
mAbs
The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can precisely assess physicochemical properties of these large and very complex drugs for the pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f183bde956423f5930af0c3d9a27c283
https://nrc-publications.canada.ca/eng/view/object/?id=633c08c1-47ae-47b0-a883-a615bb5663ce
https://nrc-publications.canada.ca/eng/view/object/?id=633c08c1-47ae-47b0-a883-a615bb5663ce
Autor:
Robert C. Tuckey, Donna M. Baldisseri, Andrzej Slominski, Elaine W. Tieu, Wei Li, Jianjun Chen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 129:163-171
CYP27A1 is a mitochondrial cytochrome P450 which can hydroxylate vitamin D3 and cholesterol at carbons 25 and 26, respectively. The product of vitamin D3 metabolism, 25-hydroxyvitamin D3, is the precursor to the biologically active hormone, 1α,25-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6124c88db697352c0d152c48e454e1
https://doi.org/10.1016/j.jsbmb.2011.11.012
https://doi.org/10.1016/j.jsbmb.2011.11.012
Publikováno v:
Biochemistry. 42:13410-13421
In addition to binding Ca(2+), the S100 protein S100B binds Zn(2+) with relatively high affinity as confirmed using isothermal titration calorimetry (ITC; K(d) = 94 +/- 17 nM). The Zn(2+)-binding site on Ca(2+)-bound S100B was examined further using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef10c5a48839e3851c309b4fe0054d9
https://doi.org/10.1021/bi035334q
https://doi.org/10.1021/bi035334q
Autor:
Keith G. Inman, Richard R. Rustandi, Ruiqing Yang, Donna M. Baldisseri, David J. Weber, Kristine E. Miller
Publikováno v:
Journal of Molecular Biology. 324:1003-1014
The solution NMR structure is reported for Ca(2+)-loaded S100B bound to a 12-residue peptide, TRTK-12, from the actin capping protein CapZ (alpha1 or alpha2 subunit, residues 265-276: TRTKIDWNKILS). This peptide was discovered by Dimlich and co-worke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7c9c5df017c4603b93e91e208229b9
https://doi.org/10.1016/s0022-2836(02)01152-x
https://doi.org/10.1016/s0022-2836(02)01152-x
Publikováno v:
Journal of Molecular Biology. 319:823-837
Olfactory marker protein (OMP) is a ubiquitous, cytoplasmic protein found in mature olfactory receptor neurons of all vertebrates. Electrophysiological and behavioral studies demonstrate that it is a modulator of the olfactory signal transduction pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d0a267ffe2e382bf95fbfaa718ff0c
https://doi.org/10.1016/s0022-2836(02)00282-6
https://doi.org/10.1016/s0022-2836(02)00282-6
Autor:
Donna M. Baldisseri, Aimee Landar, Alexander Landar, Shannon M Hamilton, Peter Nizner, David J. Weber, Keith G. Inman, Danna B. Zimmer, Richard R. Rustandi
Publikováno v:
Biochemistry. 41:788-796
S100A1, a member of the S100 protein family, is an EF-hand containing Ca(2+)-binding protein (93 residues per subunit) with noncovalent interactions at its dimer interface. Each subunit of S100A1 has four alpha-helices and a small antiparallel beta-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdbb82f72bf0c84f7a367be068bfb32
https://doi.org/10.1021/bi0118308
https://doi.org/10.1021/bi0118308
Publikováno v:
Biochemistry. 40:3439-3448
Backbone dynamics of homodimeric apo-S100B were studied by (15)N nuclear magnetic resonance relaxation at 9.4 and 14.1 T. Longitudinal relaxation (T(1)), transverse relaxation (T(2)), and the (15)N-[(1)H] NOE were measured for 80 of 91 backbone amide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91a2f72ec845cd7ea06cf18b61e8fb5
https://doi.org/10.1021/bi0027478
https://doi.org/10.1021/bi0027478
Publikováno v:
Nature Structural Biology. 7:570-574
A Ca2+ dependent conformational change in dimeric S100B(betabeta) is required for it to bind p53 and inhibit phosphorylation of this tumor suppressor in its C-terminal negative regulatory domain. A peptide derived from this region of p53 (residues 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad52ad8ee66b57fc35fd990c59927d1
https://doi.org/10.1038/76797
https://doi.org/10.1038/76797