Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Donna M Peehl"'
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146505 (2016)
Androgen receptor (AR) is expressed in normal murine and human kidneys of both genders, but its physiologic role is uncertain. Several studies showed loss of AR in renal cell carcinoma (RCC) in conjunction with increasing clinical stage and pathologi
Externí odkaz:
https://doaj.org/article/3177412e8e26452781cb5731a3fc8ebf
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124245 (2015)
To reduce treatment of indolent prostate cancer (PCa), biomarkers are needed to improve identification of patients with a low-risk of having aggressive disease. Over-treatment of these patients occurs because of uncertainty in the aggressiveness of t
Externí odkaz:
https://doaj.org/article/f453895173434c7093a626592c299b07
Autor:
Hongjuan Zhao, Ning Sun, Sarah R Young, Rosalie Nolley, Jennifer Santos, Joseph C Wu, Donna M Peehl
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64503 (2013)
Induced pluripotent stem (iPS) cells are a valuable resource for discovery of epigenetic changes critical to cell type-specific differentiation. Although iPS cells have been generated from other terminally differentiated cells, the reprogramming of n
Externí odkaz:
https://doaj.org/article/9a312760e7ba48cda1f18f89d15aff7f
Autor:
Patrick M Brauer, Yu Zheng, Mark D Evans, Carmen Dominguez-Brauer, Donna M Peehl, Angela L Tyner
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14789 (2011)
Protein tyrosine kinase 6 (PTK6), also called breast tumor kinase (BRK), is expressed in epithelial cells of various tissues including the prostate. Previously it was shown that PTK6 is localized to epithelial cell nuclei in normal prostate, but beco
Externí odkaz:
https://doaj.org/article/f2ecaa6db33d4d44ba12c4a6c998d6a6
Autor:
Donna M. Peehl, Cristian T. Badea, Thomas L. Chenevert, Heike E. Daldrup-Link, Li Ding, Lacey E. Dobrolecki, A. McGarry Houghton, Paul E. Kinahan, John Kurhanewicz, Michael T. Lewis, Shunqiang Li, Gary D. Luker, Cynthia X. Ma, H. Charles Manning, Yvonne M. Mowery, Peter J. O'Dwyer, Robia G. Pautler, Mark A. Rosen, Raheleh Roudi, Brian D. Ross, Kooresh I. Shoghi, Renuka Sriram, Moshe Talpaz, Richard L. Wahl, Rong Zhou
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 657-680 (2023)
The availability of high-fidelity animal models for oncology research has grown enormously in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment of cancer to be undertaken. This has led to increased opportunit
Externí odkaz:
https://doaj.org/article/315dd791b13b4c40966ef7abc8d61d4c
Autor:
Joao Piraquive Agudelo, Deepti Upadhyay, Dalin Zhang, Hongjuan Zhao, Rosalie Nolley, Jinny Sun, Shubhangi Agarwal, Robert A. Bok, Daniel B. Vigneron, James D. Brooks, John Kurhanewicz, Donna M. Peehl, Renuka Sriram
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1117 (2022)
Patient-derived xenografts (PDX) are high-fidelity cancer models typically credentialled by genomics, transcriptomics and proteomics. Characterization of metabolic reprogramming, a hallmark of cancer, is less frequent. Dysregulated metabolism is a ke
Externí odkaz:
https://doaj.org/article/7088b15c33834d20b41251b87f37bac7
Autor:
Susan J. Knox, Donna M. Peehl, Xuejun Li, Sarah R. Young, Stephen W. Reese, Rosalie Nolley, Hongjuan Zhao, Junqiang Tian
XLS file, 83KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7212bd63c265836c99466389a672074
https://doi.org/10.1158/1078-0432.22451403.v1
https://doi.org/10.1158/1078-0432.22451403.v1
Autor:
Charis Eng, Donna M. Peehl, Pan Zheng, Li Zhang, Gurkan Bebek, Mohammed S. Orloff, Shingo Ashida
Purpose: Recent studies suggest that tumor microenvironment (stroma) is important in carcinogenesis and progression. We sought to integrate global genomic structural and expressional alterations in prostate cancer epithelium and stroma and their asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910636fee5f5075e0b31773684f82061
https://doi.org/10.1158/1078-0432.c.6521162.v1
https://doi.org/10.1158/1078-0432.c.6521162.v1
Autor:
Erinn B. Rankin, Amato J. Giaccia, Donna M. Peehl, James D. Brooks, John T. Leppert, Rie von Eyben, Yu Rebecca Miao, Katherine C. Fuh, Anne Ernst, Anh N. Diep, Rosalie Nolley, Lei Tian, Hongjuan Zhao, Yiren Xiao
Document contains Supplemental Table 1-4:Supplementary Table S1 and Supplementary Table S2 shows the gene expression profile in 786-O and M62 cell transfected with shSCM1 and shAXL1. Supplementary Table S3 shows the List of genes with >2 fold ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6148951aa468113f808c3ee2a8107bb3
https://doi.org/10.1158/0008-5472.22422489.v1
https://doi.org/10.1158/0008-5472.22422489.v1
Autor:
Susan J. Knox, Donna M. Peehl, Xuejun Li, Sarah R. Young, Stephen W. Reese, Rosalie Nolley, Hongjuan Zhao, Junqiang Tian
Purpose: Hypoxia is an important characteristic of the solid tumor microenvironment and constitutes a barrier for effective radiotherapy. Here, we studied the effects of darinaparsin (an arsenic cytotoxin) on survival and radiosensitivity of tumor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3d1948bb4359634e26791eef3d0b79
https://doi.org/10.1158/1078-0432.c.6522189
https://doi.org/10.1158/1078-0432.c.6522189