Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Donna M, Platt"'
Autor:
Jake Valeri, Charlotte Stiplosek, Sinead M. O’Donovan, David Sinclair, Kathleen A. Grant, Ratna Bollavarapu, Donna M. Platt, Craig A. Stockmeier, Barbara Gisabella, Harry Pantazopoulos
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Contextual triggers are significant factors contributing to relapse in substance use disorders (SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as mediators of reward memories. Chondroitin sulfate pr
Externí odkaz:
https://doaj.org/article/304450224fd54ef7b09e590ab5499d6c
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionBenzodiazepines (BZs) are prescribed as anxiolytics, but their use is limited by side effects including abuse liability and daytime drowsiness. Neuroactive steroids are compounds that, like BZs, modulate the effects of GABA at the GABAA r
Externí odkaz:
https://doaj.org/article/c55cfd91072240c591fcfdd7d04a814c
Autor:
Lalit K. Golani, Donna M. Platt, Daniela Rüedi-Bettschen, Chitra Edwanker, Shenming Huang, Michael M. Poe, Roman Furtmüller, Werner Sieghart, James M. Cook, James K. Rowlett
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In order to develop improved anxiolytic drugs, 8-substituted analogs of triazolam were synthesized in an effort to discover compounds with selectivity for α2/α3 subunit-containing GABAA subtypes. Two compounds in this series, XLi-JY-DMH (6-(2-chlor
Externí odkaz:
https://doaj.org/article/a95252a7ff224cdca9d223b58e02c490
Autor:
Lais F Berro, Tanya Pareek, Jaren A Reeves-Darby, Monica L Andersen, Leonard L Howell, Donna M Platt, James K Rowlett
Publikováno v:
J Am Assoc Lab Anim Sci
Rhesus monkeys are naturally social animals, and behavioral management strategies have focused on promoting pairhousing in laboratory settings as an alternative to individual or group housing. In humans, co-sleeping can have a major impact on bed par
Publikováno v:
Developmental Psychobiology. 65
Methamphetamine use by women, even throughout pregnancy, is common. But there is limited knowledge about the effects in prenatally methamphetamine-exposed children. This study investigated how prenatal methamphetamine exposure in rats, via maternal i
Autor:
Tanya Pareek, John S. Overton, Luat T. Nguyen, Md. Toufiqur Rahman, Dishary Sharmin, James M. Cook, Donna M. Platt
Publikováno v:
Drug and alcohol dependence. 243
Cue-exposure therapy (CET) is an effective approach for anxiety-related disorders, but its effectiveness for substance use disorders is less clear. One potential means of improving CET outcomes is to include a cognitive-enhancing pharmacotherapy. Thi
Autor:
Sally L. Huskinson, Donna M. Platt, C. Austin Zamarripa, Kristen Dunaway, Morgan Brasfield, Thomas E. Prisinzano, Bruce E. Blough, Kevin B. Freeman
Publikováno v:
Pharmacol Biochem Behav
Kappa-opioid receptor (KOR) agonists have been studied as potential treatments for pain, pruritus, and substance-use disorders, but prototypical KOR agonists produce side-effects like dysphoria and sedation. Atypical KOR agonists that exhibit G-prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1714d7150d68198121a58e626c4ead9
https://europepmc.org/articles/PMC9629661/
https://europepmc.org/articles/PMC9629661/
Autor:
Cassandra D. Gipson, Paul L. Soto, Erin S. Calipari, Donna M. Platt, John D. Salamone, Rick A. Bevins
Publikováno v:
Journal of the experimental analysis of behavior. 117(3)
Autor:
Laurie J. Lynch, Katherine A. Sullivan, Eric J. Vallender, James K. Rowlett, Donna M. Platt, Gregory M. Miller
Publikováno v:
Substance Abuse: Research and Treatment, Vol 2013, Iss 7, Pp 117-126 (2013)
Externí odkaz:
https://doaj.org/article/02311b402b12402693ee31daa3b66e7c
Autor:
Kevin B. Freeman, Bruce E. Blough, M Brasfield, M E Follett, Sally L. Huskinson, Donna M. Platt, Thomas E. Prisinzano
Publikováno v:
Psychopharmacology (Berl)
Kappa-opioid receptor (KOR) agonists are antinociceptive but have side effects that limit their therapeutic utility. New KOR agonists have been developed that are fully efficacious at the KOR but may produce fewer or reduced side effects that are typ