Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Donna M, Fekete"'
Publikováno v:
Viruses, Vol 15, Iss 1, p 247 (2023)
The transmembrane protein Axl was proposed as an entry receptor for Zika virus (ZIKV) infection in vitro, but conflicting results from in vivo studies have made it difficult to establish Axl as a physiologically relevant ZIKV receptor. Both the funct
Externí odkaz:
https://doaj.org/article/f954584de2614aea9fbdbd087e46181d
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 692-700 (2018)
Summary: Zika virus (ZIKV) is associated with severe neurodevelopmental impairments in human fetuses, including microencephaly. Previous reports examining neural progenitor tropism of ZIKV in organoid and animal models did not address whether the vir
Externí odkaz:
https://doaj.org/article/7b3db2d80c23423bb3d76fd0b30ce953
Autor:
Vidhya Munnamalai, Nabilah H. Sammudin, Caryl A. Young, Ankita Thawani, Richard J. Kuhn, Donna M. Fekete
Publikováno v:
Viruses, Vol 13, Iss 9, p 1823 (2021)
Congenital Zika Syndrome (CZS) is caused by vertical transmission of Zika virus (ZIKV) to the gestating human fetus. A subset of CZS microcephalic infants present with reduced otoacoustic emissions; this test screens for hearing loss originating in t
Externí odkaz:
https://doaj.org/article/a2e18efc73b3405f8d0da62eb90e29ab
Autor:
Nabilah H. Sammudin, Vidhya Munnamalai, Ankita Thawani, Donna M. Fekete, Hannah S. Reygaerts, Richard J. Kuhn, Alexis N. Wozniak
Publikováno v:
Dev Dyn
Background Sensorineural hearing loss is an understudied consequence of congenital Zika syndrome, and balance disorders are essentially unreported to date. Also lacking is information about the susceptibility and the pathogenesis of the developing in
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132796 (2015)
The miR-183 family consists of 3 related microRNAs (miR-183, miR-96, miR-182) that are required to complete maturation of primary sensory cells in the mammalian inner ear. Because the level of these microRNAs is not uniform across hair cell subtypes
Externí odkaz:
https://doaj.org/article/8b3b73e132a1462b8a5d81087b175a04
Autor:
Nabilah H. Sammudin, Donna M. Fekete, Vidhya Munnamalai, Caryl A. Young, Richard J. Kuhn, Ankita Thawani
Publikováno v:
Viruses
Volume 13
Issue 9
Department of Biological Sciences Faculty Publications
Viruses, Vol 13, Iss 1823, p 1823 (2021)
Volume 13
Issue 9
Department of Biological Sciences Faculty Publications
Viruses, Vol 13, Iss 1823, p 1823 (2021)
Congenital Zika Syndrome (CZS) is caused by vertical transmission of Zika virus (ZIKV) to the gestating human fetus. A subset of CZS microcephalic infants present with reduced otoacoustic emissions
this test screens for hearing loss originating
this test screens for hearing loss originating
Autor:
Gabriel Lutz, Igor Jurak, Eui Tae Kim, Ju Youn Kim, Michael Hackenberg, Andrew Leader, Michelle L. Stoller, Donna M. Fekete, Matthew D. Weitzman, Donald M. Coen, Angus C. Wilson
Publikováno v:
Viruses, Vol 9, Iss 8, p 210 (2017)
Infection with herpes simplex virus-1 (HSV-1) brings numerous changes in cellular gene expression. Levels of most host mRNAs are reduced, limiting synthesis of host proteins, especially those involved in antiviral defenses. The impact of HSV-1 on hos
Externí odkaz:
https://doaj.org/article/399ba1a201cf46ed98842061f1561abc
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69314 (2013)
The mammalian inner ear subserves the special senses of hearing and balance. The auditory and vestibular sensory epithelia consist of mechanically sensitive hair cells and associated supporting cells. Hearing loss and balance dysfunction are most fre
Externí odkaz:
https://doaj.org/article/30e05e9edd9249eb834d72e479f46fb4
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e8981 (2010)
The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanis
Externí odkaz:
https://doaj.org/article/865543bdd5bf4817b2040b293e4c4201
Autor:
Vidhya Munnamalai, Donna M. Fekete
Publikováno v:
Dev Dyn
The mammalian cochlea detects sound and transmits this information to the brain. A cross section through the cochlea reveals functionally distinct epithelial domains arrayed around the circumference of a fluid-filled duct. Six major domains include t