Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Donna L. Ralph"'
Autor:
Ting Yang, Chengcheng Song, Donna L. Ralph, Portia Andrews, Matthew A. Sparks, Beverly H. Koller, Alicia A. McDonough, Thomas M. Coffman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Background A beneficial role for prostanoids in hypertension is suggested by clinical studies showing nonsteroidal anti‐inflammatory drugs, which block the production of all prostanoids, cause sodium retention and exacerbate hypertension. Among pro
Externí odkaz:
https://doaj.org/article/1e745101eca4475590b2c265fe58e7d5
Publikováno v:
Am J Physiol Cell Physiol
Kidneys continuously filter an enormous amount of sodium and adapt kidney Na+ reabsorption to match Na+ intake to maintain circulatory volume and electrolyte homeostasis. Males (M) respond to high-salt (HS) diet by translocating proximal tubule Na+/H
Autor:
Alicia A. McDonough, Kenneth E. Bernstein, Susan B. Gurley, Zhidan Xiang, Jorge F. Giani, Jonathan W. Nelson, Joshua A. Robertson, Donna L. Ralph
Publikováno v:
Am J Physiol Renal Physiol
The renal nephron consists of a series of distinct cell types that function in concert to maintain fluid and electrolyte balance and blood pressure. The renin-angiotensin system (RAS) is central to Na(+) and volume balance. We aimed to determine how
Autor:
Thomas M. Coffman, Donna L. Ralph, Rishav Adhikari, Alicia A. McDonough, Emre Dilmen, Alison N. Hollis, Susan B. Gurley, Thien A. Hoang, Fitra Rianto, Gabriel Chew, Enrico Petretto, Matthew A. Sparks, Edward J. Diaz
Publikováno v:
American Journal of Physiology : Renal Physiology, 320, F1080-F1092
American Journal of Physiology : Renal Physiology, 320, 6, pp. F1080-F1092
Am J Physiol Renal Physiol
American Journal of Physiology : Renal Physiology, 320, 6, pp. F1080-F1092
Am J Physiol Renal Physiol
Contains fulltext : 238842.pdf (Publisher’s version ) (Closed access) A major pathway in hypertension pathogenesis involves direct activation of ANG II type 1 (AT(1)) receptors in the kidney, stimulating Na(+) reabsorption. AT(1) receptors in tubul
Autor:
Alicia A. McDonough, Donna L. Ralph, Joanne Soong, Rolando Carrisoza‐Gaytan, Thomas R. Kleyman, Lisa M. Satlin
Publikováno v:
The FASEB Journal. 36
Autor:
Meena S. Madhur, Adriana Mercado, Brandon E. McFarlin, Taylor S Priver, Donna L. Ralph, Alicia A. McDonough, Yuhan Chen, Gerardo Gamba
Publikováno v:
American Journal of Physiology-Cell Physiology. 319:C757-C770
Extracellular fluid (ECF) potassium concentration ([K+]) is maintained by adaptations of kidney and skeletal muscle, responses heretofore studied separately. We aimed to determine how these organ systems work in concert to preserve ECF [K+] in male C
Publikováno v:
Hypertension. 76
Raising blood pressure stimulates pressure natriuresis (P-Nat). In males (M) Sprague Dawley rats (SDR), Na + reabsorption (T Na ) is acutely reduced by retraction of proximal tubule (PT) NHE3 to microvillar base and NaPi2 internalization. In females
Autor:
Brandon E, McFarlin, Yuhan, Chen, Taylor S, Priver, Donna L, Ralph, Adriana, Mercado, Gerardo, Gamba, Meena S, Madhur, Alicia A, McDonough
Publikováno v:
Am J Physiol Cell Physiol
Extracellular fluid (ECF) potassium concentration ([K(+)]) is maintained by adaptations of kidney and skeletal muscle, responses heretofore studied separately. We aimed to determine how these organ systems work in concert to preserve ECF [K(+)] in ma
Autor:
Sebastian A. Potthoff, Donna L. Ralph, Lajos Markó, Masudur Rahman, Oliver Vonend, Susan B. Gurley, Vikram Gupta, Annika Reil, Henning Hoch, Lars Christian Rump, Johannes Stegbauer, Lydia Hering, Mina Yakoub, Guang Yang, Alicia A. McDonough
Publikováno v:
J Am Soc Nephrol
Background Increased nerve activity causes hypertension and kidney disease. Recent studies suggest that renal denervation reduces BP in patients with hypertension. Renal NE release is regulated by prejunctional α2A-adrenoceptors on sympathetic nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d58b5bc105b19e30f80c341c9e8ed7
https://europepmc.org/articles/PMC7191918/
https://europepmc.org/articles/PMC7191918/
Autor:
Scotti D Smith, Núria M. Pastor-Soler, Alicia A. McDonough, Brandon E. McFarlin, Hillmin Andy Lei, Donna L. Ralph, Taylor S Priver
Publikováno v:
Hypertension. 74
When chronic kidney disease progresses to end stage renal disease, the optimal treatment is living kidney donation (LKD). A 10 yr prospective study of 1214 donors (PMID 27006347), reported that LKD increased risk of hypertension (HTN), by 3.64-fold,