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pro vyhledávání: '"Donna L. Nile"'
Autor:
Donna L. Nile, Colin Rae, David J. Walker, Joe Canning Waddington, Isabel Vincent, Karl Burgess, Mark N. Gaze, Robert J. Mairs, Anthony J. Chalmers
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Background Neuroblastoma accounts for 7% of paediatric malignancies but is responsible for 15% of all childhood cancer deaths. Despite rigorous treatment involving chemotherapy, surgery, radiotherapy and immunotherapy, the 5-year overall sur
Externí odkaz:
https://doaj.org/article/18c074a3dffa4f188c780def00713faa
Autor:
Donna L Nile, Audrey E Brown, Meutia A Kumaheri, Helen R Blair, Alison Heggie, Satomi Miwa, Lynsey M Cree, Brendan Payne, Patrick F Chinnery, Louise Brown, David A Gunn, Mark Walker
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115433 (2014)
Type 2 diabetes is characterised by an age-related decline in insulin secretion. We previously identified a 50% age-related decline in mitochondrial DNA (mtDNA) copy number in isolated human islets. The purpose of this study was to mimic this degree
Externí odkaz:
https://doaj.org/article/a5d3b7f6a6c14dbcae578e14fc6d4ae3
Publikováno v:
BMC Cancer
Background: \ud The radiopharmaceutical 131I-meta-iodobenzylguanidine (131I-MIBG) is an effective treatment for neuroblastoma. However, maximal therapeutic benefit from 131I-MIBG is likely to be obtained by its combination with chemotherapy. We previ