Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Donna L, Smith"'
Autor:
Sarah J Javier, Justina Wu, Donna L Smith, Fasiha Kanwal, Lindsey A Martin, Jack Clark, Amanda M Midboe
Publikováno v:
JMIR Formative Research, Vol 5, Iss 11, p e27748 (2021)
BackgroundCirrhosis, or scarring of the liver, is a debilitating condition that affects millions of US adults. Early identification, linkage to care, and retention of care are critical for preventing severe complications and death from cirrhosis. Ob
Externí odkaz:
https://doaj.org/article/b2fcc43d06aa400d836de96343461951
Autor:
Ulrike Träger, Ralph Andre, Anna Magnusson-Lind, James R.C. Miller, Colúm Connolly, Andreas Weiss, Stephan Grueninger, Edina Silajdžić, Donna L. Smith, Blair R. Leavitt, Gillian P. Bates, Maria Björkqvist, Sarah J. Tabrizi
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 388-398 (2015)
Inflammation is a growing area of research in neurodegeneration. In Huntington's disease (HD), a fatal inherited neurodegenerative disease caused by a CAG-repeat expansion in the gene encoding huntingtin, patients have increased plasma levels of infl
Externí odkaz:
https://doaj.org/article/2bb72a14457c461b9f15b194b9926f85
Autor:
Raffaella Tulino, Agnesska C Benjamin, Nelly Jolinon, Donna L Smith, Eduardo N Chini, Alisia Carnemolla, Gillian P Bates
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150682 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0145425.].
Externí odkaz:
https://doaj.org/article/243117c9159c4daaba9f9a69f9732654
Autor:
Raffaella Tulino, Agnesska C Benjamin, Nelly Jolinon, Donna L Smith, Eduardo N Chini, Alisia Carnemolla, Gillian P Bates
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145425 (2016)
Huntington's disease (HD) is a neurodegenerative disorder for which there are no disease-modifying treatments. SIRT1 is a NAD+-dependent protein deacetylase that is implicated in maintaining neuronal health during development, differentiation and age
Externí odkaz:
https://doaj.org/article/fa4ad6c77f364fdf81ee63cfbb192c31
Autor:
Justina Wu, Fasiha Kanwal, Jack A. Clark, Sarah J Javier, Lindsey A Martin, Donna L. Smith, Amanda M. Midboe
Publikováno v:
JMIR Formative Research
Background Cirrhosis, or scarring of the liver, is a debilitating condition that affects millions of US adults. Early identification, linkage to care, and retention of care are critical for preventing severe complications and death from cirrhosis. Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08683a1a765ca0b15b8e93584485ef81
http://europepmc.org/articles/PMC8663449
http://europepmc.org/articles/PMC8663449
Autor:
Michal Mielcarek, Linda Inuabasi, Marie K Bondulich, Thomas Muller, Georgina F Osborne, Sophie A Franklin, Donna L Smith, Andreas Neueder, Jim Rosinski, Ivan Rattray, Andrea Protti, Gillian P Bates
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004550 (2014)
Cardiac remodelling and contractile dysfunction occur during both acute and chronic disease processes including the accumulation of insoluble aggregates of misfolded amyloid proteins that are typical features of Alzheimer's, Parkinson's and Huntingto
Externí odkaz:
https://doaj.org/article/999732e06288452195737c7385566612
Autor:
Donna L. Smith, Ruben Portier, Ben Woodman, Emma Hockly, Amarbirpal Mahal, William E. Klunk, Xiao-Jiang Li, Erich Wanker, Karl D. Murray, Gillian P. Bates
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 6, Pp 1017-1026 (2001)
Huntington's disease (HD) is a late onset neurodegenerative disorder caused by a CAG/polyglutamine (polyQ) repeat expansion. PolyQ aggregates can be detected in the nuclei and processes of neurons in HD patients and mouse models prior to the onset of
Externí odkaz:
https://doaj.org/article/fa08d20b29484b8d8f8a3bbfc905b226
Autor:
Steven M. Asch, Thomas J. Taylor, Jennifer R. Kramer, Aanand D. Naik, Yan Liu, Abbas Rana, Ruben Hernaez, Fasiha Kanwal, Donna L. Smith, Tamar H. Taddei
Publikováno v:
JAMA Intern Med
Importance Organ scarcity means few patients with advanced liver disease undergo a transplant, making equitable distribution all the more crucial. Disparities may arise at any stage in the complex process leading up to this curative therapy. Objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a77b6480354ea944c3f19efce720ebb
https://pubmed.ncbi.nlm.nih.gov/34028505
https://pubmed.ncbi.nlm.nih.gov/34028505
Autor:
Sarah J Javier, Justina Wu, Donna L Smith, Fasiha Kanwal, Lindsey A Martin, Jack Clark, Amanda M Midboe
BACKGROUND Cirrhosis, or scarring of the liver, is a debilitating condition that affects millions of US adults. Early identification, linkage to care, and retention of care are critical for preventing severe complications and death from cirrhosis. OB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b633c0bb5adc0ddc836a36f90a7a641
https://doi.org/10.2196/preprints.27748
https://doi.org/10.2196/preprints.27748
Autor:
Michal Mielcarek, Christian Landles, Andreas Weiss, Amyaouch Bradaia, Tamara Seredenina, Linda Inuabasi, Georgina F Osborne, Kristian Wadel, Chrystelle Touller, Rachel Butler, Janette Robertson, Sophie A Franklin, Donna L Smith, Larry Park, Paul A Marks, Erich E Wanker, Eric N Olson, Ruth Luthi-Carter, Herman van der Putten, Vahri Beaumont, Gillian P Bates
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001717 (2013)
Histone deacetylase (HDAC) 4 is a transcriptional repressor that contains a glutamine-rich domain. We hypothesised that it may be involved in the molecular pathogenesis of Huntington's disease (HD), a protein-folding neurodegenerative disorder caused
Externí odkaz:
https://doaj.org/article/36f0a78b62114715a37984063f3cb2d9