Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Donna L, Cioffi"'
Autor:
Caleb L. Hamilton, Kevin A. Abney, Audrey A. Vasauskas, Mikhail Alexeyev, Li Ni, Richard E. Honkanen, Jonathan G. Scammell, Donna L. Cioffi
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Pulmonary endothelial cells express a store-operated calcium entry current ( I soc ), which contributes to inter-endothelial cell gap formation. I soc is regulated by a heterocomplex of proteins that includes the immunophilin FKBP51. FKBP51 inhibits
Externí odkaz:
https://doaj.org/article/ab5052dedbae4af08ed10bf0985bec25
Autor:
Caleb L. Hamilton, Pierre I. Kadeba, Audrey A. Vasauskas, Viktoriya Solodushko, Anna K. McClinton, Mikhail Alexeyev, Jonathan G. Scammell, Donna L. Cioffi
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
Pulmonary artery endothelial cells (PAECs) express a cation current, I SOC (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation. The large molecular weight immunophilin FKB
Externí odkaz:
https://doaj.org/article/ffeaf94c49fb46f39d598842735f275e
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135533 (2015)
Microparticles (MPs) are released constitutively and from activated cells. MPs play significant roles in vascular homeostasis, injury, and as biomarkers. The unique glycocalyx on the membrane of cells has frequently been exploited to identify specifi
Externí odkaz:
https://doaj.org/article/a6861bf54bea42229c08c4b2055410d6
S100A6 is a positive regulator of PPP5C-FKBP51-dependent regulation of endothelial calcium signaling
Autor:
Viktoriya Solodushko, Caleb L. Hamilton, Kevin A Abney, Mikhail Alexeyev, Barnita Haldar, Jonathan G. Scammell, Richard E. Honkanen, Donna L. Cioffi
Publikováno v:
FASEB J
ISOC is a cation current permeating the ISOC channel. In pulmonary endothelial cells, ISOC activation leads to formation of inter-endothelial cell gaps and barrier disruption. The immunophilin FK506-binding protein 51 (FKBP51), in conjunction with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3d8093c10f2ce3106d5e1dc71478b1
https://pubmed.ncbi.nlm.nih.gov/31916625
https://pubmed.ncbi.nlm.nih.gov/31916625
Autor:
Richard E. Honkanen, Viktoriya Solodushko, Caleb L. Hamilton, Donna L. Cioffi, Jonathan G. Scammell, Barnita Haldar
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::367c069cfd83da8bc2bf27b4364cfbf1
https://doi.org/10.1096/fasebj.2020.34.s1.01993
https://doi.org/10.1096/fasebj.2020.34.s1.01993
Pseudomonas aeruginosa(P. aeruginosa) is an important opportunistic pathogen associated with high mortality in pneumonia, sepsis, and cystic fibrosis. Lending to its ability to cause severe disease and death is its arsenal of virulence factors and ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0804c10883aaa37c08f323040316c85b
https://doi.org/10.1101/319418
https://doi.org/10.1101/319418
Autor:
Jonathan G. Scammell, Viktoriya Solodushko, Barnita Haldar, Caleb L. Hamilton, Donna L. Cioffi
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3281280e295aa6c72a42dea28339e345
https://doi.org/10.1096/fasebj.2018.32.1_supplement.917.1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.917.1
Publikováno v:
American Journal of Physiology-Cell Physiology. 308:C277-C288
Orai1 interacts with transient receptor potential protein of the canonical subfamily (TRPC4) and contributes to calcium selectivity of the endothelial cell store-operated calcium entry current ( ISOC). Orai1 silencing increases sodium permeability an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c8235a5818bd711917fe60ed929ca5
https://doi.org/10.1152/ajpcell.00063.2014
https://doi.org/10.1152/ajpcell.00063.2014
Autor:
Caleb L. Hamilton, Anna McClinton, Jonathan G. Scammell, Mikhail Alexeyev, Audrey A. Vasauskas, Donna L. Cioffi, Pierre I. Kadeba, Viktoriya Solodushko
Publikováno v:
Pulmonary Circulation
Pulmonary Circulation, Vol 8 (2018)
Pulmonary Circulation, Vol 8 (2018)
Pulmonary artery endothelial cells (PAECs) express a cation current, I SOC (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation. The large molecular weight immunophilin FKB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7482b543cc6f82dd3d142083d3f3b7b8
https://pubmed.ncbi.nlm.nih.gov/29261039
https://pubmed.ncbi.nlm.nih.gov/29261039
Publikováno v:
Pulmonary Circulation. 4:116-127
Disruption of the endothelium leads to increased permeability, allowing extravasation of macromolecules and other solutes from blood vessels. Calcium entry through a calcium-selective, store-operated calcium (SOC) channel, I soc, contributes to barri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48330e055a141b92a4e43df6a6c9f5c7
https://doi.org/10.1086/675641
https://doi.org/10.1086/675641