Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Donna K. Dang"'
Autor:
Rajdeep Das, Martin Sjöström, Raunak Shrestha, Christopher Yogodzinski, Emily A. Egusa, Lisa N. Chesner, William S. Chen, Jonathan Chou, Donna K. Dang, Jason T. Swinderman, Alex Ge, Junjie T. Hua, Shaheen Kabir, David A. Quigley, Eric J. Small, Alan Ashworth, Felix Y. Feng, Luke A. Gilbert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
It is hypothesized that there are a number of tumor specific driver genes for metastatic prostate cancer. Here, the authors perform genome-wide CRISPRi screens and integrate these data with metastatic prostate cancer functional and clinical genomics
Externí odkaz:
https://doaj.org/article/fa65632946e846318209a6540b59b6ba
Autor:
Donna K. Dang, Ben H. Park
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
Cancer cells shed naked DNA molecules into the circulation. This circulating tumor DNA (ctDNA) has become the predominant analyte for liquid biopsies to understand the mutational landscape of cancer. Coupled with next-generation sequencing, ctDNA can
Externí odkaz:
https://doaj.org/article/3e92f84318d64119921a9e4f835503bb
Autor:
Monish Ram Makena, Myungjun Ko, Allatah X. Mekile, Nanami Senoo, Donna K. Dang, John Warrington, Phillip Buckhaults, C. Conover Talbot, Jr., Steven M. Claypool, Rajini Rao
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102240- (2022)
A complex interplay between the extracellular space, cytoplasm and individual organelles modulates Ca2+ signaling to impact all aspects of cell fate and function. In recent years, the molecular machinery linking endoplasmic reticulum stores to plasma
Externí odkaz:
https://doaj.org/article/0b300ccbdec4497a989595ebae280235
Autor:
Rajini Rao, Manuj Bandral, Myungjun Ko, Hari Prasad, José P. Llongueras, Monish Ram Makena, Donna K. Dang
Legend for Supplementary Movies 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c255bcfa157e1b4857ad10a3b286e9
https://doi.org/10.1158/1541-7786.22516020
https://doi.org/10.1158/1541-7786.22516020
Autor:
Rajini Rao, Manuj Bandral, Myungjun Ko, Hari Prasad, José P. Llongueras, Monish Ram Makena, Donna K. Dang
Progression of benign tumors to invasive, metastatic cancer is accompanied by the epithelial-to-mesenchymal transition (EMT), characterized by loss of the cell-adhesion protein E-cadherin. Although silencing mutations and transcriptional repression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e19104671f9050452d231db287ce7af
https://doi.org/10.1158/1541-7786.c.6541257
https://doi.org/10.1158/1541-7786.c.6541257
Autor:
Monish Ram, Makena, Myungjun, Ko, Allatah X, Mekile, Nanami, Senoo, Donna K, Dang, John, Warrington, Phillip, Buckhaults, C Conover, Talbot, Steven M, Claypool, Rajini, Rao
Publikováno v:
Redox Biology
A complex interplay between the extracellular space, cytoplasm and individual organelles modulates Ca2+ signaling to impact all aspects of cell fate and function. In recent years, the molecular machinery linking endoplasmic reticulum stores to plasma
Autor:
Raunak Shrestha, Eric J. Small, Felix Y. Feng, Jason T. Swinderman, Emily A. Egusa, Rajdeep Das, Alan Ashworth, David A. Quigley, Martin Sjöström, Christopher Yogodzinski, William S. Chen, Donna K. Dang, Junjie Tony Hua, Jonathan Chou, Luke A. Gilbert, Alex Y. Ge, Shaheen Kabir, Lisa N. Chesner
Publikováno v:
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Genomic sequencing of thousands of tumors has revealed many genes associated with specific types of cancer. Similarly, large scale CRISPR functional genomics efforts have mapped genes required for cancer cell proliferation or survival in hundreds of
Publikováno v:
Cancers
Cancers, Vol 13, Iss 259, p 259 (2021)
Volume 13
Issue 2
Cancers, Vol 13, Iss 259, p 259 (2021)
Volume 13
Issue 2
The secretory pathway Ca2+-ATPase SPCA2 is a tumor suppressor in triple receptor negative breast cancer (TNBC), a highly aggressive molecular subtype that lacks tailored treatment options. Low expression of SPCA2 in TNBC confers poor survival prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fad0c46fa1227a9465273e18f141e2e
https://doi.org/10.1101/2020.11.12.379685
https://doi.org/10.1101/2020.11.12.379685