Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Donna J. Page"'
Autor:
Donna J. Page, Raphael Thuret, Lakshmi Venkatraman, Tokiharu Takahashi, Katie Bentley, Shane P. Herbert
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3139-3151.e5 (2019)
Summary: Angiogenesis is driven by the coordinated collective branching of specialized leading “tip” and trailing “stalk” endothelial cells (ECs). While Notch-regulated negative feedback suppresses excessive tip selection, roles for positive
Externí odkaz:
https://doaj.org/article/d2eb7ce923394870b15b027b2afb2391
Publikováno v:
Monaghan, R M, Page, D J, Ostergaard, P & Keavney, B D 2021, ' The physiological and pathological functions of VEGFR3 in cardiac and lymphatic development and related diseases ', Cardiovascular research, vol. 117, no. 8, pp. 1877-1890 . https://doi.org/10.1093/cvr/cvaa291, https://doi.org/10.1093/cvr/cvaa291
Cardiovascular Research
Monaghan, R M, Page, D J, Ostergaard, P & Keavney, B D 2021, ' The physiological and pathological functions of VEGFR3 in cardiac and lymphatic development and related diseases ', Cardiovascular research, vol. 117, no. 8, pp. 1877-1890 . https://doi.org/10.1093/cvr/cvaa291
Cardiovascular Research
Monaghan, R M, Page, D J, Ostergaard, P & Keavney, B D 2021, ' The physiological and pathological functions of VEGFR3 in cardiac and lymphatic development and related diseases ', Cardiovascular research, vol. 117, no. 8, pp. 1877-1890 . https://doi.org/10.1093/cvr/cvaa291
Vascular endothelial growth factor receptors (VEGFRs) are part of the evolutionarily conserved VEGF signalling pathways that regulate the development and maintenance of the body’s cardiovascular and lymphovascular systems. VEGFR3, encoded by the FL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28988ac9287174028910e2622c11da38
https://doi.org/10.1093/cvr/cvaa291
https://doi.org/10.1093/cvr/cvaa291
Autor:
Tarryn L. Botha, Sarah Kraus, Nakita Laing, Stephen Kamuli, Zandile Booi, Ashley Chin, Timothy F Spracklen, Paul R. Kasher, Gasnat Shaboodien, Bernard Keavney, Donna J. Page, Ntobeko A B Ntusi
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1977ea0dd91b913caaa9c13f3c337a
https://doi.org/10.1161/circgen.120.003138
https://doi.org/10.1161/circgen.120.003138
Publikováno v:
Heart
The four finalists for the 2019 British Cardiovascular Society (BCS) Young Investigator Award (YIA) were selected from a competitive pool of young researchers. At the BCS meeting in Manchester last June, each finalist gave a 10 min oral presentation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de3be0e9ba05152b0bde99adabf99e2
https://e-space.mmu.ac.uk/623976/
https://e-space.mmu.ac.uk/623976/
Autor:
Martin Baron, John O'Sullivan, Elisavet Fotiou, Kathryn E. Hentges, Jeroen Breckpot, Mathieu Bourgey, Barbara J.M. Mulder, Alex V. Postma, William G. Newman, Connie R. Bezzina, Frances A. Bu'Lock, Marc Gewillig, Koenraad Devriendt, Graham Stuart, Heather J. Cordell, Bernard Keavney, David Brook, Robert Eveleigh, Simon G. Williams, Matthieu J. Miossec, James R. Bentham, Mauro Santibanez-Koref, Louise Sutcliffe, Mark Lathrop, Ana Töpf, Donna J. Page, Sally L. Dunwoodie, Richard M. Monaghan, Sanjeev S. Bhaskar, Kerry Setchfield, Guillaume Bourque, David S. Winlaw, Shoumo Bhattacharya, Graeme C.M. Black
Publikováno v:
Young Investigators Award.
Introduction There is strong evidence from familial recurrence studies for a genetic predisposition to sporadic, non-syndromic Tetralogy of Fallot (TOF). TOF is the most common, cyanotic congenital heart disease (CHD) phenotype yet the cause for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd97b941c4bba120bf4aed8b79315e29
https://doi.org/10.1136/heartjnl-2019-bcs.226
https://doi.org/10.1136/heartjnl-2019-bcs.226
Autor:
Kathryn E. Hentges, Robert Eveleigh, Mathieu Bourgey, Barbara J.M. Mulder, William G. Newman, Shoumo Bhattacharya, Sally L. Dunwoodie, Frances A. Bu'Lock, Ana Töpf, Richard M. Monaghan, Elisavet Fotiou, Graham Stuart, Simon G. Williams, Marc Gewillig, Connie R. Bezzina, Alex V. Postma, Guillaume Bourque, Kerry Setchfield, G. Mark Lathrop, Koenraad Devriendt, D Winlaw, J. David Brook, Heather J. Cordell, Graeme C.M. Black, James R. Bentham, Bernard Keavney, Mauro Santibanez-Koref, Matthieu J. Miossec, Louise Sutcliffe, Donna J. Page, Sanjeev S. Bhaskar, Martin Baron, John O'Sullivan, Jeroen Breckpot
Publikováno v:
Page, D J, Miossec, M J, Williams, S G, Monaghan, R M, Fotiou, E, Cordell, H J, Sutcliffe, L, Topf, A, Bourgey, M, Bourque, G, Eveleigh, R, Dunwoodie, S L, Winlaw, D S, Bhattacharya, S, Breckpot, J, Devriendt, K, Gewillig, M, Brook, J D, Setchfield, K J, Bu'Lock, F A, O'Sullivan, J, Stuart, G, Bezzina, C R, Mulder, B J M, Postma, A V, Bentham, J R, Baron, M, Bhaskar, S S, Black, G C, Newman, W G, Hentges, K E, Lathrop, G M, Santibanez-Koref, M & Keavney, B D 2019, ' Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot ', Circulation research, vol. 124, no. 4, pp. 553-563 . https://doi.org/10.1161/CIRCRESAHA.118.313250, https://doi.org/10.1161/CIRCRESAHA.118.313250
Circulation research, 124(4), 553-563. Lippincott Williams and Wilkins
Circulation research, 124(4), 553-563. Lippincott Williams and Wilkins
Rationale: Familial recurrence studies provide strong evidence for a genetic component to the predisposition to sporadic, nonsyndromic Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease phenotype. Rare genetic variants have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ef130c9628a90cd791742dc7a84be5
https://lirias.kuleuven.be/handle/123456789/631749
https://lirias.kuleuven.be/handle/123456789/631749
Autor:
Kyle Harrington, Shane P. Herbert, Guilherme Costa, Holly E. Lovegrove, Donna J. Page, Shilpa Chakravartula, Katie Bentley
Publikováno v:
Costa*, G, Harrington*, K, Lovegrove*, H, Page, D, Chakravartula, S, Bentley, K & Herbert, S 2016, ' Asymmetric division coordinates collective cell migration in angiogenesis ', Nature Cell Biology, vol. 18, pp. 1292-1301 . https://doi.org/10.1038/ncb3443
Costa, G, Harrington, K I, Lovegrove, H E, Page, D J, Chakravartula, S, Bentley, K & Herbert, S P 2016, ' Asymmetric division coordinates collective cell migration in angiogenesis ', Nature cell biology, vol. 18, no. 12, pp. 1292-1301 . https://doi.org/10.1038/ncb3443
Costa, G, Harrington, K I, Lovegrove, H E, Page, D J, Chakravartula, S, Bentley, K & Herbert, S P 2016, ' Asymmetric division coordinates collective cell migration in angiogenesis ', Nature cell biology, vol. 18, no. 12, pp. 1292-1301 . https://doi.org/10.1038/ncb3443
The asymmetric division of stem or progenitor cells generates daughters with distinct fates and regulates cell diversity during tissue morphogenesis. However, roles for asymmetric division in other more dynamic morphogenetic processes, such as cell m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cb04415b495a336661e5071e129582
https://doi.org/10.1038/ncb3443
https://doi.org/10.1038/ncb3443
Autor:
Shane P. Herbert, Tokiharu Takahashi, Raphael Thuret, Lakshmi Venkatraman, Donna J. Page, Katie Bentley
SUMMARYBlood vessel formation by angiogenesis is critical for tissue development, homeostasis and repair, and is frequently dysregulated in disease[1–3]. Angiogenesis is triggered by vascular endothelial growth factor receptor-2/3 (VEGFR) signallin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8ecd6a17fbba42f1dec746cc16bf9b
Autor:
Donna J. Page, Matthieu J. Miossec, Simon G. Williams, Elisavet Fotiou, Richard M. Monaghan, Heather J. Cordell, Louise Sutcliffe, Ana Topf, Mathieu Bourgey, Guillaume Bourque, Robert Eveleigh, Sally L. Dunwoodie, David S. Winlaw, Shoumo Bhattacharya, Jeroen Breckpot, Koenraad Devriendt, Marc Gewillig, David Brook, Kerry Setchfield, Frances A. Bu’Lock, John O’Sullivan, Graham Stuart, Connie Bezzina, Barbara J.M. Mulder, Alex V. Postma, James R. Bentham, Martin Baron, Sanjeev S. Bhaskar, Graeme C. Black, William G. Newman, Kathryn E. Hentges, Mark Lathrop, Mauro Santibanez-Koref, Bernard D. Keavney
AimsFamilial recurrence studies provide strong evidence for a genetic component to the predisposition to sporadic, non-syndromic Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease (CHD) phenotype. Rare genetic variants have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68be040d4834c06a04efd344c72ccb08
Publikováno v:
Cardiovascular Research. 114:S116-S116
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744d8cf9c6e07fe4b9a2c76555fa82f1
https://doi.org/10.1093/cvr/cvy060.337
https://doi.org/10.1093/cvr/cvy060.337