Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Donna J Koslowsky"'
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12235 (2010)
Mitochondrial mRNA editing in Trypanosoma brucei requires the specific interaction of a guide RNA with its cognate mRNA. Hundreds of gRNAs are involved in the editing process, each needing to target their specific editing domain within the target mes
Externí odkaz:
https://doaj.org/article/7424945d2c3e47e2abf1425dec09d8d0
Autor:
Donna J. Koslowsky, Jennifer L. Ekstrom, Charles G. Hoogstraten, David A. Dickson, Neil A. White, Pakoyo F. Kamba
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Pentatricopeptide repeat (PPR) proteins, a helical repeat family of organellar RNA binding proteins, play essential roles in post-transcriptional RNA processing. In Trypanosoma brucei, an expanded family of PPR proteins localize to the parasite’s s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae50e5137c4064e42f01a68933976bb
http://link.springer.com/article/10.1038/s41598-018-34377-9
http://link.springer.com/article/10.1038/s41598-018-34377-9
Autor:
Brianna L Tylec, Laurie K. Read, Donna J. Koslowsky, Laura E. Kirby, Rachel M. Simpson, Yijun Sun, Runpu Chen
Publikováno v:
Nucleic Acids Research
Most mitochondrial mRNAs in kinetoplastids require extensive uridine insertion/deletion editing to generate translatable open reading frames. Editing is specified by trans-acting gRNAs and involves a complex machinery including basal and accessory fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e969af280427e94264bbcb4df6b70124
https://pubmed.ncbi.nlm.nih.gov/30698753
https://pubmed.ncbi.nlm.nih.gov/30698753
Autor:
Donna J. Koslowsky, Laura E. Kirby
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005989 (2017)
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005989 (2017)
Trypanosoma brucei is transmitted between mammalian hosts by the tsetse fly. In the mammal, they are exclusively extracellular, continuously replicating within the bloodstream. During this stage, the mitochondrion lacks a functional electron transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decb4fb20da89b1f477ea4913064ab03
https://doi.org/10.1101/187732
https://doi.org/10.1101/187732
Autor:
Jennifer K. Knight, Mary A. Bedell, Farahad Dastoor, Norris Armstrong, Rosa A. Moscarella, John Merrill, Nancy Guild, Mark Urban-Lurain, Susan Erster, Michelle K. Smith, Cori L. Fata-Hartley, Hamish S. Greig, Tessa C. Andrews, Jon Stolzfus, David W. Hall, Neta Dean, Jennifer M. Martin, Luanna B. Prevost, Karen N. Pelletreau, Robert M. Northington, Brian J. Olsen, Donna J. Koslowsky, Paula P. Lemons, Jill S. McCourt, Ross H. Nehm
Publikováno v:
CourseSource. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7c009851e096e310ee9112bdfc888b
https://doi.org/10.24918/cs.2016.15
https://doi.org/10.24918/cs.2016.15
Publikováno v:
Experimental Parasitology. 124:453-458
Two genes from Trypanosoma brucei brucei are predicted to encode Fe(II)- and alpha-ketoglutarate-dependent enzymes related to fungal thymine 7-hydroxylase. Transcription of the thymine hydroxylase-like genes is up-regulated in the bloodstream form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389575a6c28e5909aa7be0c3399b64a3
https://doi.org/10.1016/j.exppara.2009.11.012
https://doi.org/10.1016/j.exppara.2009.11.012
Autor:
Donna J. Koslowsky
Publikováno v:
Trends in Parasitology. 25:252-255
Trypanosomes undergo extreme physiological changes to adapt to different environments as they cycle between hosts. Adaptation to the different environments has evolved an energy metabolism involving a mitochondrion with an unusual genome. Recently, A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9ad695884f470b17312a149f155d05
https://doi.org/10.1016/j.pt.2009.03.008
https://doi.org/10.1016/j.pt.2009.03.008
Autor:
Susan D. Waaland, Donna J. Koslowsky
Publikováno v:
Journal of Phycology. 23:638-648
Fusion of somatic cells from different geographic isolates of Griffithsia pacifica is followed by a cytoplasmic incompatibility reaction (CIR)5 in the cytoplasm donated by only one of the isolates. This CIR is characterized by the aggregation, fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5118c2aed0df38f6deea1d4eb32861c0
https://doi.org/10.1111/j.1529-8817.1987.tb04218.x
https://doi.org/10.1111/j.1529-8817.1987.tb04218.x
Publikováno v:
Eukaryotic Cell. 3:862-869
In Trypanosoma brucei , two classes of transcripts are produced from two distinct mitochondrial genome components. Guide RNAs (gRNAs) are usually minicircle encoded and exist as primary transcripts, while the maxicircle-encoded rRNAs and mRNAs are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8d0fb3bae462ec1851768d2265294f
https://doi.org/10.1128/ec.3.4.862-869.2004
https://doi.org/10.1128/ec.3.4.862-869.2004
Publikováno v:
RNA Biology. 1:27-33
The most dramatic example of RNA editing is found in the mitochondria of trypanosomes. In these organisms, U-insertions/deletions can create mRNAs that are twice as large as the gene that encodes them. Guide RNAs (gRNAs) that are complementary to sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5784601c640607a63a76868ee27d14f8
https://doi.org/10.4161/rna.1.1.898
https://doi.org/10.4161/rna.1.1.898