Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Donna J, Skow"'
Autor:
Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTCo-formulation of multiple drug products is an efficient and convenient approach to simultaneously deliver multiple biotherapeutics with the potentially added benefit of a synergistic therapeutic effect. However, co-formulation also increases
Externí odkaz:
https://doaj.org/article/1494bc863c804d3eb9523d2ed2f12fcb
Autor:
Ryan M, Fryer, Khing Jow, Ng, Suzanne G, Nodop Mazurek, Lori, Patnaude, Donna J, Skow, Akalushi, Muthukumarana, Kyle E, Gilpin, Roger M, Dinallo, Daniel, Kuzmich, John, Lord, Sulagna, Sanyal, Hui, Yu, Christian, Harcken, Matthew A, Cerny, Matthew C, Cerny, Eugene R, Hickey, Louise K, Modis
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 348:421-431
Bile acids (BAs) and BA receptors, including G protein-coupled bile acid receptor 1 (GPBAR1), represent novel targets for the treatment of metabolic and inflammatory disorders. However, BAs elicit myriad effects on cardiovascular function, although t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d49d84857eb02b186bf7f533e87e9b
https://doi.org/10.1124/jpet.113.210005
https://doi.org/10.1124/jpet.113.210005
Autor:
Zheng-yu Long, George E. Wright, Richard Storer, Karsten A. Holm, Neal C. Brown, Andrzej Manikowski, Donna J. Skow, Kimberly A. Foster, Serge Lamothe, Paul M. Tarantino, Irina Motorina, Michelle M. Butler, Chengxin Zhi, William A. LaMarr, Edward J. Dix
Publikováno v:
Journal of Medicinal Chemistry. 48:7063-7074
Numerous 3-substituted-6-(3-ethyl-4-methylanilino)uracils (EMAU) have been synthesized and screened for their capacity to inhibit the replication-specific bacterial DNA polymerase IIIC (pol IIIC) and the growth of Gram+ bacteria in culture. Direct al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8975de033417761467d60c8c160fadd5
https://doi.org/10.1021/jm050517r
https://doi.org/10.1021/jm050517r
Autor:
Ryan O. Stephenson, Kimberly A. Foster, Marjorie H. Barnes, Donna J. Skow, Neal C. Brown, Michelle M. Butler, William A. LaMarr
Publikováno v:
Protein Expression and Purification. 27:90-97
Enterococcus faecalis (Ef) dnaE and polC, the respective genes encoding the DNA replication-specific DNA polymerase III E and DNA polymerase III C, were cloned and engineered for expression in Escherichia coli as hexahistidine (his6)-tagged recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f66850773e2f07e55fc197916af242b
https://doi.org/10.1016/s1046-5928(02)00577-6
https://doi.org/10.1016/s1046-5928(02)00577-6
Autor:
Donna J. Skow, Kimberly A. Foster, Michelle M. Butler, Ryan O. Stephenson, Patrick T. Lyden, William A. LaMarr
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3770-3775
The 6-anilinouracils (AUs) constitute a new class of bactericidal antibiotics selective against gram-positive (Gr + ) organisms. The AU family of compounds specifically inhibits a novel target, replicative DNA polymerase Pol IIIC. Like other antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c8e4e7af9def4d0166ecf7e8e4f8afb
https://doi.org/10.1128/aac.46.12.3770-3775.2002
https://doi.org/10.1128/aac.46.12.3770-3775.2002
Autor:
George E. Wright, Kimberly A. Foster, Marjorie H. Barnes, Lauren Kustigian, Michelle M. Butler, Donna J. Skow, Patrick T. Lyden, Terry L. Bowlin, Chengxin Zhi, William A. LaMarr, Neal C. Brown
Publikováno v:
Antimicrobial agents and chemotherapy. 51(1)
The anilinouracils (AUs) such as 6-(3-ethyl-4-methylanilino)uracil (EMAU) are a novel class of gram-positive, selective, bactericidal antibacterials which inhibit pol IIIC, the gram-positive-specific replicative DNA polymerase. We have linked various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63af83edf478a5126b972f454d4a9f38
https://pubmed.ncbi.nlm.nih.gov/17074800
https://pubmed.ncbi.nlm.nih.gov/17074800
Autor:
Kimberly A, Foster, Marjorie H, Barnes, Ryan O, Stephenson, Michelle M, Butler, Donna J, Skow, William A, LaMarr, Neal C, Brown
Publikováno v:
Protein expression and purification. 27(1)
Enterococcus faecalis (Ef) dnaE and polC, the respective genes encoding the DNA replication-specific DNA polymerase III E and DNA polymerase III C, were cloned and engineered for expression in Escherichia coli as hexahistidine (his6)-tagged recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16c3e8c14ca97492690defaf51f2bc75
https://pubmed.ncbi.nlm.nih.gov/12509989
https://pubmed.ncbi.nlm.nih.gov/12509989