Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Donna Horncastle"'
Autor:
Jayson Wang, Ian C. Talbot, Nabil S. El-Masry, James Hollingshead, Donna Horncastle, Mona El-Bahrawy, Ian Tomlinson, Malcolm R. Alison
PURPOSE: The expression of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) is associated with poor prognosis in sporadic colorectal carcinoma (CRC). EGFR inhibitors are approved for the treatment of refract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d79f10d360eb6da82f90e139120494
https://doi.org/10.1007/s12029-011-9330-9
https://doi.org/10.1007/s12029-011-9330-9
Autor:
Douglas C Macdonald, Donna Horncastle, Alison H. Banham, Mark Bower, Furrat Amen, K. Elderfield, Kikkeri N. Naresh, Edward Kanfer
Publikováno v:
Histopathology. 51:70-79
Aims: To validate and improve the existing algorithm (proposed by Hans et al.) to classify diffuse large B-cell lymphoma (DLBCL). Methods and results: Tissue microarrays constructed from 81 patients with DLBCL were studied by immunohistochemistry for
Autor:
Robert K. Nuttall, Dylan R. Edwards, Jon S. Friedland, Justin A. Green, Donna Horncastle, Paul T. Elkington, James E. Harris, Manuel B. Graeber
Publikováno v:
The Journal of Immunology. 178:1199-1207
CNS tuberculosis (CNS-TB) is the most deadly form of tuberculous disease accounting for 10% of clinical cases. CNS-TB is characterized by extensive tissue destruction, in which matrix metalloproteinases (MMPs) may play a critical role. We investigate
Autor:
Kikkeri N. Naresh, Pritesh Trivedi, Donna Horncastle, K. Elderfield, Furrat Amen, Simon D. Wagner
Publikováno v:
Leukemia & Lymphoma. 48:1510-1513
Bcl-6 is expressed in germinal centre derived B-cell non-Hodgkin lymphomas including diffuse large B-cell lymphoma (DLBCL) and is likely to play a major role in driving proliferation of a subset of DLBCLs, especially those of germinal centre B-cell s
Autor:
James E. Harris, Donna Horncastle, Manuel B. Graeber, Paul T. Elkington, Marc Fernandez-Vilaseca, Jon S. Friedland
Publikováno v:
The FASEB Journal. 21:356-365
Matrix metalloproteinase-9 (MMP-9) activity is implicated in pathogenesis of central nervous system tuberculosis (CNS-TB). IFNgamma, a key cytokine in TB, usually inhibits MMP-9 secretion. Addition of IFNgamma to conditioned media from M. tb-infected
Autor:
Laura D. C. Lopez-Pascua, Cecilia O'Kane, Donna Horncastle, Paul T. Elkington, Jenny E. Emerson, Joseph J. Boyle, Jon S. Friedland
Publikováno v:
The Journal of Immunology. 175:5333-5340
Pulmonary cavitation is vital to the persistence and spread of Mycobacterium tuberculosis (MTb), but mechanisms underlying this lung destruction are poorly understood. Fibrillar type I collagen provides the lung’s tensile strength, and only matrix
Autor:
Kikkeri N. Naresh, Nye-Thane Ngo, Amin Rahemtulla, M. Klammer, Brodie C, Irvin A. Lampert, Chrissy Giles, Donna Horncastle
Publikováno v:
Journal of clinical pathology. 62(11)
Background and aims: Antigen expression of multiple myeloma (MM) cells is heterogeneous. We have investigated the clinical impact of expression of some of the commonly used immunohistochemical markers in the diagnostic work-up of bone marrow trephine
Autor:
Pandelis Philippidis, Kenneth M. Taylor, Dorian O. Haskard, Viola Leung, Donna Horncastle, Clive Landis, Joseph J. Boyle, Sandra Cantilena
Publikováno v:
The FASEB Journal. 22
Autor:
R.C.G. Russell, Belinda A. Theis, Donna Horncastle, Gordon Stamp, Mona El-Bahrawy, Ian Tomlinson, Andrew D. Rowan
Publikováno v:
The American journal of surgical pathology. 32(1)
Solid pseudopapillary tumor (SPT) of the pancreas is an uncommon neoplasm of uncertain lineage. They have been shown to express nuclear beta-catenin believed to be due to mutations of the beta-catenin gene. The aim of this study was to investigate th
Autor:
K. Elderfield, Irvin A. Lampert, Amin Rahemtulla, Rahul Joshi, Donna Horncastle, Kikkeri N. Naresh
Publikováno v:
Journal of clinical pathology. 61(2)
Aims: Multiple myeloma (MM) guidelines in the UK do not advocate performing bone marrow trephine biopsy (BMTB) during follow-up. In a recent study, it was found that the plasma cell per cent (PC%) in BMTB performed at the time of autologous stem cell