Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Donna Denton"'
Autor:
Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-24 (2024)
Abstract Autophagy, the process of elimination of cellular components by lysosomal degradation, is essential for animal development and homeostasis. Using the autophagy-dependent Drosophila larval midgut degradation model we identified an autophagy r
Externí odkaz:
https://doaj.org/article/48b9fe21c5fc45f2b5b559b3895df865
Publikováno v:
Cells, Vol 13, Iss 4, p 347 (2024)
Cell death plays an essential function in organismal development, wellbeing, and ageing. Many types of cell deaths have been described in the past 30 years. Among these, apoptosis remains the most conserved type of cell death in metazoans and the mos
Externí odkaz:
https://doaj.org/article/8b3a7f19742646f6a96cac0ad682ce4b
Autor:
Andrew I. Webb, Shannon Nicolson, Xin Jiang, Donna Denton, Sharad Kumar, Jarrod J. Sandow, Sonia Dayan, Tianqi Xu, Jantina A. Manning
Publikováno v:
Autophagy. 17:2734-2749
Macroautophagy/autophagy is a highly conserved lysosomal degradative pathway important for maintaining cellular homeostasis. Much of our current knowledge of autophagy is focused on the initiation steps in this process. Recently, an understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818049298eadac624d8470aa58b2e36b
https://doi.org/10.1080/15548627.2020.1838105
https://doi.org/10.1080/15548627.2020.1838105
Publikováno v:
Cell Death Differ
The removal of superfluous and unwanted cells is a critical part of animal development. In insects the steroid hormone ecdysone, the focus of this review, is an essential regulator of developmental transitions, including molting and metamorphosis. Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bc6b1910d571acecaf1de86276f30e
https://doi.org/10.1038/s41418-019-0456-9
https://doi.org/10.1038/s41418-019-0456-9
Autor:
Sharad Kumar, Donna Denton
Publikováno v:
Cell Death & Differentiation. 26:605-616
Autophagy-dependent cell death can be defined as cell demise that has a strict requirement of autophagy. Although autophagy often accompanies cell death following many toxic insults, the requirement of autophagic machinery for cell death execution, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8703fdf6b86650d5b4ca35f61b19050d
https://doi.org/10.1038/s41418-018-0252-y
https://doi.org/10.1038/s41418-018-0252-y
Autor:
Donna Denton, Mark van den Hurk, Timothy J. Sargeant, Bridget Milky, Robert J. Adams, Sanjna Singh, Julian M. Carosi, Leanne K. Hein, Sharad Kumar, Cedric Bardy
Publikováno v:
Autophagy
The macroautophagy/autophagy-lysosome axis enables the clearance and degradation of cytoplasmic components including protein aggregates, damaged organelles and invading pathogens. Protein aggregation and lysosomal system dysfunction in the brain are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505e80b5c302656b5bac0986404d82d9
https://hdl.handle.net/11541.2/146169
https://hdl.handle.net/11541.2/146169
Autor:
Tianqi, Xu, Shannon, Nicolson, Jarrod J, Sandow, Sonia, Dayan, Xin, Jiang, Jantina A, Manning, Andrew I, Webb, Sharad, Kumar, Donna, Denton
Publikováno v:
Autophagy
Macroautophagy/autophagy is a highly conserved lysosomal degradative pathway important for maintaining cellular homeostasis. Much of our current knowledge of autophagy is focused on the initiation steps in this process. Recently, an understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d71bbbe64e786b33f49f4a813a34b514
https://pubmed.ncbi.nlm.nih.gov/33112206
https://pubmed.ncbi.nlm.nih.gov/33112206
Publikováno v:
Cell Death Differ
Refereed/Peer-reviewed Tauopathies define a broad range of neurodegenerative diseases that encompass pathological aggregation of the microtubule associated protein tau. Although tau aggregation is a central feature of these diseases, their underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6d4ab86305ae0d114df7f9878df0cb
https://pubmed.ncbi.nlm.nih.gov/33473181
https://pubmed.ncbi.nlm.nih.gov/33473181
Publikováno v:
Progress in molecular biology and translational science. 172
Autophagy has important functions in normal physiology to maintain homeostasis and protect against cellular stresses by the removal of harmful cargos such as dysfunctional organelles, protein aggregates and invading pathogens. The deregulation of aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9d14de18bb9e3ae4c16c8bf0b193470
https://pubmed.ncbi.nlm.nih.gov/32620249
https://pubmed.ncbi.nlm.nih.gov/32620249
Autophagy has important functions in normal physiology to maintain homeostasis and protect against cellular stresses by the removal of harmful cargos such as dysfunctional organelles, protein aggregates and invading pathogens. The deregulation of aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add1515fbc8ed3b970801537e3038396
https://doi.org/10.1016/bs.pmbts.2020.01.005
https://doi.org/10.1016/bs.pmbts.2020.01.005