Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Donna Dail"'
Autor:
Vangipuram S. Rangan, Amy Manney, Mark Saewert, Ang Liu, Binodh DeSilva, Donna Dail, Jennifer Cummings, Renuka Pillutla, Alex Kozhich, Heather Myler, Chetana Rao, Jian Wang, Brian K. Hoffpauir
Publikováno v:
Bioanalysis. 8:519-531
Background: The bioanalytical strategy for antibody–drug conjugates (ADC) includes multiple integrated measurements of pharmacologically relevant ADC. Methods & results: Three ligand-binding assays were validated for the measurement of total antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3681fec20a59b885ac063763e7b9d22b
https://doi.org/10.4155/bio.16.13
https://doi.org/10.4155/bio.16.13
Autor:
Jian Wang, Mei-Chen Sung, Binodh DeSilva, Robert Neely, Jennifer Cummings, Donna Dail, Steven P. Piccoli, John Lute, Heather Myler, Alexander T. Kozhich, Richard L. Wong, Thomas D. Kempe, Wendy Freebern, Anne-Françoise Aubry, Renuka Pillutla, Heather E. Vezina, Mark E. Arnold, Vangipuram S. Rangan, Mark Saewert, Bonnie Wang, Frank Zambito, David Passmore, Amy Manney, Shrikant Deshpande, Huidong Gu, Ang Liu
Publikováno v:
Bioanalysis. 7:1569-1582
Background: The bioanalytical strategy for antibody–drug conjugates (ADC) includes numerous measurements integrally designed to provide comprehensive characterization of PK, PD and immunogenicity. This manuscript describes the utilization of reagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717842dd5b587299aeb25835b7250bb7
https://doi.org/10.4155/bio.15.80
https://doi.org/10.4155/bio.15.80
Publikováno v:
Journal of Neuroimmunology. 166:180-188
Many multiple sclerosis (MS) patients treated with IFNbeta develop anti-IFNbeta antibodies, which can interfere with the bioactivity of the injected cytokine, i.e., antibody-mediated decreased bioactivity (ADB). The precise levels of anti-IFNbeta ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4399e41ff9d6813356af62c888c188e
https://doi.org/10.1016/j.jneuroim.2005.06.003
https://doi.org/10.1016/j.jneuroim.2005.06.003
Autor:
Diego Cadavid, Andrew R. Pachner, Kavitha Narayan, Yunhong Bai, Lena Pak, Marie Sondey, Donna Dail
Publikováno v:
Annals of Neurology. 56:361-370
Borrelia burgdorferi sensu lato, the causative organism of Lyme borreliosis, is a heterogeneous group of spirochetes, consisting of at least three pathogenic species. To test the hypothesis that the genetic heterogeneity is the reason for the clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bafdbe596d7b29e34811b6f522521fa
https://doi.org/10.1002/ana.20192
https://doi.org/10.1002/ana.20192
Autor:
Kavi Narayan, Emir Hodzic, Stephen W. Barthold, Diego Cadavid, Yunhong Bai, Andrew R. Pachner, Donna Dail, Marie Hurd
Publikováno v:
Infection and Immunity. 71:7087-7098
Lyme borreliosis is a multisystemic disease caused by various genospecies of the spirocheteBorrelia burgdorferi. To investigate muscle involvement in the nonhuman primate (NHP) model of Lyme disease, 16 adultMacaca mulattaanimals inoculated with stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa154f8187f79a3f285f43408aead401
https://doi.org/10.1128/iai.71.12.7087-7098.2003
https://doi.org/10.1128/iai.71.12.7087-7098.2003
Publikováno v:
Molecular Diagnosis. 7:17-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0abbf61eb46ba522dcf3cf226e2484e7
https://doi.org/10.2165/00066982-200307010-00004
https://doi.org/10.2165/00066982-200307010-00004
Autor:
L. Li, Sunlian Feng, Emir Hodzic, Stephen W. Barthold, Andrew R. Pachner, Donna Dail, L. Gurey
Publikováno v:
Clinical and Vaccine Immunology. 9:1348-1355
The immune response to Borrelia burgdorferi , the causative agent of Lyme disease, is complex. We studied the immunoglobulin M (IgM) and IgG antibody response to N40Br, a sensu stricto strain, in the rhesus macaque(nonhuman primate [NHP]) model of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22076aed25f886ad11c537764ce2db3
https://doi.org/10.1128/cdli.9.6.1348-1355.2002
https://doi.org/10.1128/cdli.9.6.1348-1355.2002
Publikováno v:
Cytokine. 19:297-307
Inflammation in skeletal muscle is a consistent feature of Lyme borreliosis, both in the human disease and experimental models. This study had two goals: to evaluate the expression of selected pro-inflammatory and chemokine genes in skeletal muscle i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdeee867b7c6d389cf0347ccd4b2a72
https://doi.org/10.1006/cyto.2002.1973
https://doi.org/10.1006/cyto.2002.1973
Autor:
Donna Dail, Sarah Pachner, Stephen W. Barthold, Emir Hodzic, Andrew R. Pachner, Gale Shu, Diego Cadavid
Publikováno v:
Annals of Neurology. 50:330-338
The relationship between chronic infection, antispirochetal immunity, and inflammation is unknown in Lyme neuroborreliosis. In the nonhuman primate (NHP) model of Lyme neuroborreliosis, we measured spirochetal density in the nervous system and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c72e414263f424113f107f1ff3361a3
https://doi.org/10.1002/ana.1287
https://doi.org/10.1002/ana.1287
Autor:
Libin Li, Andrew R. Pachner, Kavitha Narayan, Sheela Amrute, Diego Cadavid, Donna Dail, Patricia Fitzgerald-Bocarsly
Publikováno v:
Annals of neurology. 57(6)
Lyme neuroborreliosis (LNB) is a chronic infection in which B-cell activation, plasma cell infiltration, and enhanced Ig production in infected tissue are prominent feature. However, little is known about how B cells and plasma cells invade and persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcda3044da9074b19d8072c26186658
https://pubmed.ncbi.nlm.nih.gov/15929033
https://pubmed.ncbi.nlm.nih.gov/15929033