Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Donna D. Strong"'
Autor:
Chandrasekhar Kesavan, Anjali Das, Preeya Goyal, Christian S. Jackson, Donna D. Strong, Richard M. Strong
Publikováno v:
Diagnostics, Vol 13, Iss 17, p 2807 (2023)
Many veterans deployed to Gulf War areas suffer from persistent chronic diarrhea that is disabling and affects their quality of life. The causes for this condition have eluded investigators until recently and recent literature has shed light on the e
Externí odkaz:
https://doaj.org/article/6e5c3eb3754f49b4a46bf3b2dca16b07
Publikováno v:
Journal of Bone and Mineral Research. 6:1285-1294
Recent evidence suggests that cytokines, in addition to regulating hematopoiesis and immune functions, may be important paracrine regulators of bone turnover. Interleukin-1 (IL-1) and IL-6 are cytokines that are produced by and affect both hematopoie
Autor:
Mark Rehage, Kristy D. Howard, Laura A. Pérez-Casellas, Donna D. Strong, Thomas A. Linkhart, Xiaoying Wang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1789:78-87
Insulin-like growth factor binding protein 5 (IGFBP5) is expressed in many cell types including osteoblasts and modulates IGF activities. IGFBP5 may affect osteoblasts and bone formation, in part by mechanisms independent of binding IGFs. The highly
Autor:
Jon E. Wergedal, Thomas A. Linkhart, K.-H. William Lau, Shin-Tai Chen, Matilda H.-C. Sheng, David J. Baylink, Donna D. Strong, Charles H. Rundle
Publikováno v:
The Journal of Gene Medicine. 10:229-241
Background An in vivo gene therapy strategy was developed to accelerate bone fracture repair. Methods Direct injection of a murine leukemia virus-based vector targeted transgene expression to the proliferating periosteal cells arising shortly after f
Publikováno v:
Archives of Biochemistry and Biophysics. 465:72-81
This study characterized the murine osteoclastic protein-tyrosine phosphatase (PTP-oc) promoter located within intron 12 of the Glepp1 gene. A 2-kb DNA fragment containing the putative intronic promoter showed strong promoter activity in pre-osteocla
Autor:
Marlon G. Minera, Mark E. Reeves, Subburaman Mohan, Donna D. Strong, Yousef G. Amaar, Laurice K. Hatran
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L1185-L1190
Recently, the Ras association domain family 1 gene ( RASSF1) has been identified as a Ras effector encoding two major mRNA forms, RASSF1A and RASSF1C, derived by alternative promoter selection and alternative mRNA splicing. RASSF1A is a tumor suppres
Publikováno v:
Analytical Biochemistry. 310:15-26
We have constructed a single plasmid-, Tc1-like transposon-based gene transfer vector, termed the Prince Charming vector (pPC). The pPC vector was constructed by ligating the CMV-driven "Sleeping Beauty" transposase gene downstream to the Tc1-like tr
Autor:
Kin-Hing William Lau, L. R. Donahue, Donna D. Strong, Weikuan Gu, Xin-Min Li, Wesley G. Beamer, Subburaman Mohan, Bouchra Edderkaoui, David J. Baylink
Publikováno v:
Genetica. 114:1-9
One QTL and genes and phenotypes have been localized in the region between 92 cM and 95 cM of mouse chromosome 1. The QTL locus contributes to approximately 40% of the variation of the peak bone density between C57BL/6J (B6) and CAST/EiJ (CAST) strai
Publikováno v:
Growth Hormone & IGF Research. 11:368-377
All-trans -retinoic acid (atRA) inhibits osteoblast marker gene expression and markedly increases expression of insulin-like growth factor binding protein-6 (IGFBP-6) in human osteoblasts. The possibility that IGFBP-6 inhibits the osteoblast phenotyp
Publikováno v:
Journal of Cellular Biochemistry. 75:566-577
Basic helix-loop-helix (bHLH) transcription factors have been shown to play an important role in controlling cell type determination and differentiation. TWIST, a member of the bHLH transcription factor family, is involved in the development of mesod