Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Donna Collins-McMillen"'
Autor:
Kristen Zarrella, Pierce Longmire, Sebastian Zeltzer, Donna Collins-McMillen, Meaghan Hancock, Jason Buehler, Justin M Reitsma, Scott S Terhune, Jay A Nelson, Felicia Goodrum
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011185 (2023)
Innate immune responses are crucial for limiting virus infection. However, viruses often hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta herpesvirus which establishes a life-long latent infection. Defining the vi
Externí odkaz:
https://doaj.org/article/d85e8154b8e44746b556114c61bcbb75
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Human cytomegalovirus (HCMV) is a beta herpesvirus that persists for life in the majority of the world's population. The persistence of HCMV in the human population is due to the exquisite ability of herpesviruses to establish a latent infection that
Externí odkaz:
https://doaj.org/article/14a360ff0c364f2784e12492e5f654ea
Autor:
Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected ce
Externí odkaz:
https://doaj.org/article/e112ec564a7b40c191ff06dc9080fbc1
Autor:
Emily V. Stevenson, Donna Collins-McMillen, Jung Heon Kim, Stephen J. Cieply, Gretchen L. Bentz, Andrew D. Yurochko
Publikováno v:
Viruses, Vol 6, Iss 2, Pp 782-807 (2014)
The wide range of disease pathologies seen in multiple organ sites associated with human cytomegalovirus (HCMV) infection results from the systemic hematogenous dissemination of the virus, which is mediated predominately by infected monocytes. In add
Externí odkaz:
https://doaj.org/article/d06780e9e14a470386ea7ca4de64f54d
Autor:
Donna Collins-McMillen, Liudmila Chesnokova, Byeong-Jae Lee, Heather L. Fulkerson, Reynell Brooks, Bailey S. Mosher, Andrew D. Yurochko
Publikováno v:
Viruses, Vol 10, Iss 10, p 533 (2018)
Human cytomegalovirus (HCMV) infection of peripheral blood monocytes plays a key role in the hematogenous dissemination of the virus to multiple organ systems following primary infection or reactivation of latent virus in the bone marrow. Monocytes h
Externí odkaz:
https://doaj.org/article/3618929b813b4b618df42780c762cdb8
Publikováno v:
Viruses, Vol 10, Iss 8, p 444 (2018)
Human cytomegalovirus (HCMV) is a beta herpesvirus that establishes a life-long persistence in the host, like all herpesviruses, by way of a latent infection. During latency, viral genomes are maintained in a quieted state. Virus replication can be r
Externí odkaz:
https://doaj.org/article/c26d4dc061d84765b78b38fe222c03b2
Autor:
Luwanika Mlera, Donna Collins-McMillen, Sebastian Zeltzer, Jason C. Buehler, Melissa Moy, Kristen Zarrella, Katie Caviness, Louis Cicchini, David J. Tafoya, Felicia Goodrum
SummaryLiver X receptor (LXR) signaling broadly restricts virus replication; however, the mechanisms of restriction are poorly defined. Here, we demonstrate that the LXR-inducible cellular E3 ligase IDOL (inducible degrader of low-density lipoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18abd65d2627562ba6590e09448ba6e5
https://doi.org/10.1101/2022.11.15.516687
https://doi.org/10.1101/2022.11.15.516687
Autor:
Andrew E. Hale, Nathaniel J. Moorman, Suzu Igarashi, Erik M. Lenarcic, Jeremy P. Kamil, Felicia Goodrum, Donna Collins-McMillen
Publikováno v:
Proc Natl Acad Sci U S A
Human progenitor cells (HPCs) support human cytomegalovirus (HCMV) latency, and their differentiation along the myeloid lineage triggers cellular cues that drive reactivation. A key step during HCMV reactivation in latently infected HPCs is reexpress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d87c4b665009cc2054106116609ba91
https://doi.org/10.1073/pnas.2002651117
https://doi.org/10.1073/pnas.2002651117
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2244
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60-90%. HCMV is the leading cause of congenital infections and poses a great health risk to immunocompromised individuals. Although HCMV infection is typically asymptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13e4ba6221861749f21e5c51ca38bc71
https://pubmed.ncbi.nlm.nih.gov/33555579
https://pubmed.ncbi.nlm.nih.gov/33555579
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b4fd01fc2591b7799169847ee67486
https://doi.org/10.1007/978-1-0716-1111-1_1
https://doi.org/10.1007/978-1-0716-1111-1_1