Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Donna Cerabona"'
Autor:
Donna Cerabona, Stéphane Schurmans, Stéphanie Gayral, Ying He, Elizabeth A. Sierra Potchanant, Jeff R. Gehlhausen, Grzegorz Nalepa, Zejin Sun, Zahi Abdul Sater
Publikováno v:
Molecular and Cellular Biology. 37
The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular metabolism. Previous studies revealed that INPP5E, the inositol polyphosphate-5-phosphatase that is mutated in the developmental disorders Joubert and
Autor:
Zahi Abdul Sater, Grzegorz Nalepa, Zejin Sun, Elizabeth A. Sierra Potchanant, Ying He, Donna Cerabona, Jeff R. Gehlhausen
Publikováno v:
Molecular and Cellular Biology
The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular metabolism. Previous studies revealed that INPP5E, the inositol polyphosphate-5-phosphatase that is mutated in the developmental disorders Joubert and
Autor:
Jin Yuan, Grzegorz Nalepa, Steven D. Rhodes, Feng Chun Yang, Yong Zheng He, Donna Cerabona, Shi Chen, Karl Staser, Jeff R. Gehlhausen, D. Wade Clapp, Su Jung Park, Zejin Sun, Matthew Shew, Yi Zeng, Keshav Menon, David A. Ingram
Publikováno v:
Journal of Clinical Investigation. 123:329-334
Neurofibromatosis type 1 (NF1) predisposes individuals to the development of juvenile myelomonocytic leukemia (JMML), a fatal myeloproliferative disease (MPD). In genetically engineered murine models, nullizygosity of Nf1, a tumor suppressor gene tha
Fanconi anemia (FA) is an inherited disorder of genomic instability associated with high risk of myelodysplasia and acute myeloid leukemia (AML). Young mice deficient in FA core complex genes do not naturally develop cancer, hampering preclinical stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23efa4d5ed6a98482bbef16a643bf383
https://europepmc.org/articles/PMC5131786/
https://europepmc.org/articles/PMC5131786/
Autor:
Justin K. Mack, Theresa A. Guise, Donna Cerabona, Keith R. Stayrook, Hai H Bui, Maria Niewolna, Khalid S. Mohammad, Daniel F. Edwards, Pierrick G.J. Fournier, David L. Waning
Mechanistic understanding of the preferential homing of circulating tumor cells to bone and their perturbation on bone metabolism within the tumor-bone microenvironment remains poorly understood. Alteration in both transforming growth factor β (TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe469d16090e1bf092b126f4ca56124
https://europepmc.org/articles/PMC4495778/
https://europepmc.org/articles/PMC4495778/
Autor:
Ying He, Donna Cerabona, Elizabeth A. Sierra Potchanant, Zejin Sun, Grzegorz Nalepa, Zahi Abdul Sater
Publikováno v:
Blood. 126:1211-1211
The Fanconi anemia (FA/BRCA) signaling network prevents bone marrow failure and cancer by protecting genomic integrity. Biallelic germline mutations within this gene network result in Fanconi anemia, an inherited bone marrow failure syndrome characte
The expression of toxic viral proteins for the purpose of eliminating distinct populations of cells, while leaving the rest of an organism unaffected, is a valuable method for analyzing development. Using the Gal4-UAS system, we employed the M2(H37A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bee32f7389c95e88625b6eaf9340446
https://europepmc.org/articles/PMC3174484/
https://europepmc.org/articles/PMC3174484/
Autor:
Donna Cerabona, Grzegorz Nalepa, Zahi Abdul Sater, Ying He, Elizabeth A. Sierra Potchanant, Zejin Sun
Publikováno v:
Experimental Hematology. 43:S56
Publikováno v:
Blood. 124:357-357
Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure, multiple congenital anomalies, and genomic instability resulting in predisposition to cancer. Disruption of the FA signaling network impairs multiple genome-house
Autor:
Helmut Hanenberg, Donna Cerabona, Su Jung Park, Rikki Enzor, Grzegorz Nalepa, Zahi Abdul Sater, Zejin Sun, D. Wade Clapp
Publikováno v:
Blood. 122:801-801
Fanconi anemia (FA) is a heterogenous genome instability syndrome with a high risk of cancer. The FA proteins are essential for interphase DNA damage repair. However, it is incompletely understood why FA-deficient cells also develop gross aneuploidy