Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Donna C. Ford"'
Autor:
Nicola J. Walker, Elizabeth A. Clark, Donna C. Ford, Helen L. Bullifent, Erin V. McAlister, Melanie L. Duffield, K. Ravi Acharya, Petra C. F. Oyston
Publikováno v:
Open Biology, Vol 2, Iss 12 (2012)
The need for new antibiotics has become pressing in light of the emergence of antibiotic-resistant strains of human pathogens. Yersinia pestis, the causative agent of plague, is a public health threat and also an agent of concern in biodefence. It is
Externí odkaz:
https://doaj.org/article/e7bbae35ac114011b4e3646356157531
Publikováno v:
Microbiology. 160:2710-2717
Mg2+has been shown to be an important signal controlling gene regulation via the PhoPQ two-component regulatory system for a range of Gram-negative bacteria, includingYersinia pestisandYersinia pseudotuberculosis. The magnesium ion transporter MgtB i
Autor:
Andrey V. Karlyshev, Petra C. F. Oyston, Ian A. Cooper, Ali Atas, Donna C. Ford, Alan M. Seddon, Brendan W. Wren
Publikováno v:
BMC Microbiology
Background Although bacterial peptidases are known to be produced by various microorganisms, including pathogenic bacteria, their role in bacterial physiology is not fully understood. In particular, oligopeptidases are thought to be mainly involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f631b4f0b93ad5078652f8728e86bf3a
https://eprints.kingston.ac.uk/id/eprint/36723/1/Karlyshev-A-36723-VoR.pdf
https://eprints.kingston.ac.uk/id/eprint/36723/1/Karlyshev-A-36723-VoR.pdf
Autor:
K. Ravi Acharya, Donna C. Ford, Nicola J. Walker, Elizabeth A. Clark, Ian A. Cooper, Petra C. F. Oyston
Publikováno v:
The Journal of Biological Chemistry
Resistance to antibiotics is a problem not only in terms of healthcare but also biodefense. Engineering of resistance into a human pathogen could create an untreatable biothreat pathogen. One such pathogen is Yersinia pestis, the causative agent of p
Autor:
Richard W. Titball, Ian A. Cooper, Petra C. F. Oyston, Olivia L. Champion, Sarah L. James, Melanie Duffield, Andrey V. Karlyshev, Brendan W. Wren, Donna C. Ford
Publikováno v:
Microbiology. 155:1516-1522
We report that larvae of the wax moth (Galleria mellonella) are susceptible to infection with the human enteropathogenYersinia pseudotuberculosisat 37 °C. Confocal microscopy demonstrated that in the initial stages of infection the bacteria were tak
Autor:
Petra C. F. Oyston, Olivia L. Champion, Melanie Duffield, Donna C. Ford, Richard W. Titball, Brendan W. Wren, Ian A. Cooper, Andrey V. Karlyshev
Publikováno v:
Microbiology (Reading, England). 157(Pt 4)
Manganese has an important yet undefined role in the virulence of many bacterial pathogens. In this study we confirm that a null mutation in Yersinia pseudotuberculosis mntH reduces intracellular manganese accumulation. An mntH mutant was susceptible
Autor:
Marc Bayliss, Melanie Duffield, Erin V. McAlister, Petra C. F. Oyston, Ian A. Cooper, Donna C. Ford
Publikováno v:
Molecular bioSystems. 6(12)
Many genes have been listed as putatively essential for bacterial viability in the Database of Essential Genomes (DEG), although few have been experimentally validated. By prioritising targets according to the criteria suggested by the Research and T
Autor:
Erin V. McAlister, K. Ravi Acharya, Donna C. Ford, Helen L. Bullifent, Melanie Duffield, Nicola J. Walker, Petra C. F. Oyston, Elizabeth A. Clark
Publikováno v:
Open Biology, Vol 2, Iss 12 (2012)
Open Biology
Open Biology
The need for new antibiotics has become pressing in light of the emergence of antibiotic-resistant strains of human pathogens. Yersinia pestis , the causative agent of plague, is a public health threat and also an agent of concern in biodefence. It i
Autor:
Jian Song, Chris Stubben, Jason D. Gans, Bryan Lingard, Richard W. Titball, Brendan W. Wren, Anna de Rochefort, Melanie Duffield, Petra C. F. Oyston, Ian A. Cooper, Murray Wolinsky, Andrey V. Karlyshev, Donna C. Ford
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 501 (2009)
BMC Genomics
BMC Genomics
Background New and improved antimicrobial countermeasures are urgently needed to counteract increased resistance to existing antimicrobial treatments and to combat currently untreatable or new emerging infectious diseases. We demonstrate that computa