Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Donna Bassolino"'
Publikováno v:
Protein Science. 5:578-592
The new functionality of the program CONGEN (Bruccoleri RE, Karplus M, 1987, Biopolymers 26:137-168; Bassolino-Klimas D et al., 1996, Protein Sci 5:593-603) has been applied for energy refinement of two previously determined solution NMR structures,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff300bf11d0f03a405e870634d5984b
https://doi.org/10.1002/pro.5560050403
https://doi.org/10.1002/pro.5560050403
Autor:
Robert E. Bruccoleri, Stanley R. Krystek, Roberto Tejero, William J. Metzler, Gaetano T. Montelione, Donna Bassolino-Klimas
Publikováno v:
Protein Science. 5:593-603
A new functional representation of NMR-derived distance constraints, the flexible restraint potential, has been implemented in the program CONGEN (Bruccoleri RE, Karplus M, 1987, Biopolymers 26:137-168) for molecular structure generation. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1918a263d29d9c199ae684fdbf9577c
https://doi.org/10.1002/pro.5560050404
https://doi.org/10.1002/pro.5560050404
Publikováno v:
Journal of the American Chemical Society. 117:4118-4129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28fdedfc8fb857b6009bde6b584865dc
https://doi.org/10.1021/ja00119a028
https://doi.org/10.1021/ja00119a028
Publikováno v:
The International Journal of Supercomputer Applications and High Performance Computing. 8:6-23
Although computer simulation of biological molecules has seen widespread growth and is widely accepted as an important biochemical tool, it is hampered by lim ited computing resources. Biomolecular systems, by necessity, contain a large number of int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3158eff7da08072eac11466c21792d1
https://doi.org/10.1177/109434209400800103
https://doi.org/10.1177/109434209400800103
Publikováno v:
Biochemistry. 32:12624-12637
To elucidate the mechanism of solute diffusion through lipid bilayer membranes, nearly 4 ns of molecular dynamics simulations of solutes in phospholipid bilayers was conducted. The study, the first atomic level study of solute diffusion in a lipid bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21acab0487f75360a55f05b212dedffe
https://doi.org/10.1021/bi00210a010
https://doi.org/10.1021/bi00210a010
Publikováno v:
The Journal of Chemical Physics. 99:5547-5559
We report molecular dynamics simulations of water hydrating a lipid (dimyristoylphosphatidylcholine) monolayer under conditions chosen to eliminate simulation artifacts. These simulations provide a description of the behavior of the membrane–water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02aed8fc3e08432548ac397832a2040b
https://doi.org/10.1063/1.465947
https://doi.org/10.1063/1.465947
Publikováno v:
Proteins: Structure, Function, and Genetics. 14:465-474
A directed conformational search algorithm using the program CONGEN (ref. 3), which samples backbone conformers, is described. The search technique uses information from the partially built structures to direct the search process and is tested on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9627fecb3c65f6567808f62b1108e6b8
https://doi.org/10.1002/prot.340140407
https://doi.org/10.1002/prot.340140407
Publikováno v:
Protein Science. 1:1465-1476
A model structure has been constructed for a monoclonal anti-dinitrophenyl antibody. The antibody, ANO2, has been sequenced and cloned (Anglister, J., Frey, T., & McConnell, H.M., 1984, Biochemistry 23, 1138-1142). Its amino acid sequence shows strik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090088b954c81e1768cf1241f673d4a4
https://doi.org/10.1002/pro.5560011108
https://doi.org/10.1002/pro.5560011108
Autor:
Thomas B. Lavoie, Steven Sheriff, Leonard P. Adam, Yanting Huang, Donna Bassolino-Klimas, Manorama Patel, Robert H. Stoffel, Yeheng Zhu, Prakash Taunk, Kevin Kish, Terry R. Stouch, David S. Taylor, Rex A. Parker, Jeffrey A. Robl, David R. Magnin, William R. Ewing, Thomas Harrity, Ligaya M. Simpkins, Richard B. Sulsky, Jacobson Bruce L
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(12)
Herein we report the first disclosure of biphenyl azoles that are nanomolar binders of adipocyte fatty acid binding protein (aFABP or aP2) with up to thousand-fold selectivity against muscle fatty acid binding protein and epidermal fatty acid binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4defe80b4eb513046a8cc8f836dd6990
https://pubmed.ncbi.nlm.nih.gov/17502136
https://pubmed.ncbi.nlm.nih.gov/17502136
Publikováno v:
Molecular immunology. 35(8)
The ragweed allergens Amb t 5 and Amb a 5 are among the smallest inhaled protein allergens known, containing a single, immunodominant T-cell epitope. In this study we analyzed the B-cell epitope structure of Amb t 5. The three-dimensional structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bdfeca9d6274107fbe82b0a6075402
https://pubmed.ncbi.nlm.nih.gov/9798650
https://pubmed.ncbi.nlm.nih.gov/9798650