Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Donna, Armentano"'
Autor:
Maritza Oñate, Alejandra Catenaccio, Gabriela Martínez, Donna Armentano, Geoffrey Parsons, Bredford Kerr, Claudio Hetz, Felipe A. Court
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/45f215a4415d48dba36be165c2bcc87b
Autor:
Sirkka Kyostio-Moore, Patricia Berthelette, Susan Piraino, Cathleen Sookdeo, Bindu Nambiar, Robert Jackson, Brenda Burnham, Catherine R O'Riordan, Seng H Cheng, Donna Armentano
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Recombinant adeno-associated viral (rAAV) vectors containing oversized genomes provide transgene expression despite low efficiency packaging of complete genomes. Here, we characterized the properties of oversized rAAV2/8 vectors (up to 5.4 kb) encodi
Externí odkaz:
https://doaj.org/article/dc83fa3e7b174a09885970c39aa9a954
Autor:
David W. Souza, Donna Armentano
Publikováno v:
BioTechniques, Vol 26, Iss 3, Pp 502-508 (1999)
pAdvantage is a rapid cloning system for generating recombinant adenoviruses. The system is based on manipulating the fulllength adenovirus genome as a stable plasmid in E. coli using intron-encoded endonucleases. These intron-encoded endonucleases c
Externí odkaz:
https://doaj.org/article/dd8bc3ee810645fd8e27bb438981fd35
Autor:
Samuel C. Wadsworth, Abraham Scaria, Donna Armentano, Karen A. Vincent, John M. Martin, Yuxia Luo, Seng H. Cheng, Amy Frederick
Publikováno v:
Human Gene Therapy Methods. 28:124-138
Adeno-associated virus (AAV) producer cell lines are created via transfection of HeLaS3 cells with a single plasmid containing three components (the vector sequence, the AAV rep and cap genes, and a selectable marker gene). As this plasmid contains b
Autor:
Patricia Berthelette, Bindu Nambiar, Donna Armentano, Cathleen Sookdeo, Brenda Burnham, Susan Piraino, Sirkka Kyostio-Moore, Shelley Nass, Karen A. Vincent, Seng H. Cheng, Catherine R. O'Riordan, David W. Souza, Robert B. Jackson
Publikováno v:
Human gene therapy methods. 28(1)
Several ongoing clinical studies are evaluating recombinant adeno-associated virus (rAAV) vectors as gene delivery vehicles for a variety of diseases. However, the production of vectors with genomes >4.7 kb is challenging, with vector preparations fr
Autor:
Yuxia Luo, Eric Pastor, Bruce Sol, John M. Martin, Karen A. Vincent, Michelle Joubert, Amy Frederick, Samuel C. Wadsworth, Donna Armentano, Robert B. Jackson, Francis Poulin
Publikováno v:
Human Gene Therapy Methods. 24:253-269
Adeno-associated virus (AAV) producer cell lines represent an effective method for large-scale production of AAV vectors. We set out to evaluate and characterize the use of an abbreviated protocol to generate "masterwells" (MWs; a nonclonal cell popu
Autor:
Bredford Kerr, Donna Armentano, Geoffrey Parsons, Felipe A. Court, Maritza Oñate, Gabriela Martínez, Alejandra Catenaccio, Claudio Hetz
Publikováno v:
Scientific Reports
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Scientific reports
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Scientific reports
Although protein-folding stress at the endoplasmic reticulum (ER) is emerging as a driver of neuronal dysfunction in models of spinal cord injury and neurodegeneration, the contribution of this pathway to peripheral nerve damage remains poorly explor
Autor:
David F. Bishop, Seng H. Cheng, Maciej E. Domaradzki, Robert J. Desnick, Makiko Yasuda, Donna Armentano
Publikováno v:
The Journal of Gene Medicine. 9:806-811
Background Acute intermittent porphyria (AIP) is an autosomal dominant disorder caused by the half-normal activity of hydroxymethylbilane synthase (HMB-synthase). Affected individuals can experience episodic, life-threatening, acute neurological atta
Autor:
Elizabeth Hutto, Wei-Lien Chuang, Gregory A. Grabowski, Seng H. Cheng, Kerry Anne McEachern, John Marshall, Jennifer B. Nietupski, Jennifer Johnson, Donna Armentano
Publikováno v:
The Journal of Gene Medicine. 8:719-729
Background Gaucher disease is the most common of the lysosomal storage disorders. The primary manifestation is the accumulation of glucosylceramide (GL-1) in the macrophages of liver and spleen (Gaucher cells), due to a deficiency in the lysosomal hy
Autor:
Patricia Berthelette, Monica Dias Figueiredo, Sirkka Kyostio-Moore, Donna Armentano, Cathy Sookdeo
Publikováno v:
Molecular Therapy. 24:S153-S154
Osteoarthritis (OA) is one of the more common causes of lameness in dogs and is estimated to affect approximately 20% of dogs >1 year old. OA is a progressive and degenerative disease that results in pain, inflammation and reduced joint mobility. Nov