Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Dongyue Zhuang"'
Autor:
Robert B. Piel, Valerie R. McElliott, James B. Stanton, Dongyue Zhuang, Sally A. Madsen-Bouterse, Linda K. Hamburg, Robert D. Harrington, David A. Schneider
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Nor98-like atypical scrapie is a sporadic disease that affects the central nervous system of sheep and goats that, in contrast to classical scrapie, is not generally regarded as naturally transmissible. However, infectivity has been demonstrated via
Externí odkaz:
https://doaj.org/article/19f61a61cac545cdaf83eb446475511c
Autor:
Sally A Madsen-Bouterse, Margaret A Highland, Rohana P Dassanayake, Dongyue Zhuang, David A Schneider
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204281 (2018)
The risk of classical scrapie transmission in small ruminants is highest during the neonatal period with the placenta recognized as a significant source of infection. Milk has also been identified as a source of scrapie with sheep-to-sheep transmissi
Externí odkaz:
https://doaj.org/article/0bb83cb48b9c45aca80735c1c0660245
Autor:
Rohana P. Dassanayake, Katherine I. O'Rourke, Sally A. Madsen-Bouterse, Dongyue Zhuang, Aru Balachandran, Gordon Mitchell, David A. Schneider
Publikováno v:
The Journal of General Virology
Development of mice expressing either ovine (Tg338) or cervid (TgElk) prion protein (PrP) have aided in characterization of scrapie and chronic wasting disease (CWD), respectively. Experimental inoculation of sheep with CWD prions has demonstrated th
Autor:
Thomas C. Truscott, David A. Schneider, Katherine I. O'Rourke, Rohana P. Dassanayake, Sally A. Madsen-Bouterse, Dongyue Zhuang
Publikováno v:
Prion. 10:153-164
To assess scrapie infectivity associated with caprine-origin tissues, bioassay can be performed using kids, lambs or transgenic mice expressing caprine or ovine prion (PRNP) alleles, but the incubation periods are fairly long. Although several classi
Autor:
David A. Schneider, Rohana P. Dassanayake, Sally A. Madsen-Bouterse, Margaret A. Highland, Dongyue Zhuang
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204281 (2018)
PLoS ONE
PLoS ONE
The risk of classical scrapie transmission in small ruminants is highest during the neonatal period with the placenta recognized as a significant source of infection. Milk has also been identified as a source of scrapie with sheep-to-sheep transmissi
Autor:
David A. Schneider, Dongyue Zhuang, Katherine I. O'Rourke, Thomas C. Truscott, Sally A. Madsen-Bouterse, Rohana P. Dassanayake
Publikováno v:
The Journal of General Virology
The placenta of domestic sheep plays a key role in horizontal transmission of classical scrapie. Domestic goats are frequently raised with sheep and are susceptible to classical scrapie, yet potential routes of transmission from goats to sheep are no
Autor:
O'Rourke, Katherine I.1 korourke@vetmed.wsu.edu, Dongyue Zhuang1, Truscott, Thomas C.1, Huijan Yan2, Schneider, David A.1
Publikováno v:
BMC Veterinary Research. 2011, Vol. 7 Issue 1, p7-16. 10p.
Publikováno v:
Biochemical and Biophysical Research Communications. 423:770-774
The protein misfolding cyclic amplification (PMCA) assay allows for detection of prion protein misfolding activity in tissues and fluids from sheep with scrapie where it was previously undetected by conventional western blot and immunohistochemistry
Autor:
Telmo Graça, Donald P. Knowles, David A. Schneider, Andrew G. Hughson, Byron Caughey, Rohana P. Dassanayake, Sally A. Madsen-Bouterse, Christina D. Orrú, Dongyue Zhuang
Publikováno v:
The Journal of general virology. 97(3)
Real-time quaking-induced conversion (RT-QuIC) is a rapid, specific and highly sensitive prion seeding activity detection assay that uses recombinant prion protein (rPrPSen) to detect subinfectious levels of the abnormal isoforms of the prion protein
Autor:
Robert D. Harrington, David A. Schneider, H. Denny Liggitt, Katherine I. O'Rourke, Denise M. Newsom, Dongyue Zhuang
Publikováno v:
Comparative Immunology, Microbiology and Infectious Diseases. 34:387-397
Scrapie is a prion-associated transmissible spongiform encephalopathy (TSE) of sheep and goats, and frequently serves as a comparative model for other prion diseases, such as chronic wasting disease and bovine spongiform encephalopathy. TSEs are uniq