Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Dongyin, Guan"'
Autor:
Dongyin Guan, Hosung Bae, Dishu Zhou, Ying Chen, Chunjie Jiang, Cam Mong La, Yang Xiao, Kun Zhu, Wenxiang Hu, Trang Minh Trinh, Panpan Liu, Ying Xiong, Bishuang Cai, Cholsoon Jang, Mitchell A. Lazar
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Rhythmic intraorgan communication coordinates environmental signals and the cell-intrinsic clock to maintain organ homeostasis. Hepatocyte-specific KO of core components of the molecular clock Rev-erbα and -β (Reverb-hDKO) alters cholesterol and li
Externí odkaz:
https://doaj.org/article/ac13e9643cb543ef922d4d50742d316b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/7e35f9afcf5b4659911e8d3a15550639
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Diurnal oscillation persists throughout the body and plays an essential role in maintaining physiological homeostasis. Disruption of diurnal rhythm contributes to many diseases including type 2 diabetes. The regulatory mechanism of the transcription-
Externí odkaz:
https://doaj.org/article/203b638e90c14daa8d22858527dd473e
Autor:
Huiping Liu, Justin Lathia, Stanton L. Gerson, Jeremy Rich, Arnold I. Caplan, Alvaro Alvarado, Maksim Sinyuk, Erin Mulkearns-Hubert, Monica Venere, Chris Hubert, Dongyin Guan, Damian J. Junk, Mary Doherty, Xia Liu, Golam Kibria, Valery Adorno-Cruz
The list of talks, speaker names, and their affiliations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5601b12916c9d3b000a5ad135d15041
https://doi.org/10.1158/0008-5472.22407806.v1
https://doi.org/10.1158/0008-5472.22407806.v1
Autor:
Lanfang Zhang, Dongyin Guan
Publikováno v:
Civil Engineering and Urban Research, Volume 1 ISBN: 9781003334064
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4eb29fb619ee8169defacb8c43021ae
https://doi.org/10.1201/9781003334064-2
https://doi.org/10.1201/9781003334064-2
Autor:
Dongyin, Guan, Mitchell A, Lazar
Publikováno v:
Semin Liver Dis
Circadian rhythms are approximately 24-hour cycles of variation in physiological processes, gene expression, and behavior. They result from the interplay of internal biological clocks with daily environmental rhythms, including light/dark and feeding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6763babc81a419035ef56827e9804732
https://doi.org/10.1055/a-1792-4240
https://doi.org/10.1055/a-1792-4240
Autor:
Wenxiang Hu, Chunjie Jiang, Mindy Kim, Yang Xiao, Hannah J. Richter, Dongyin Guan, Kun Zhu, Brianna M. Krusen, Arielle N. Roberts, Jessica Miller, David J. Steger, Mitchell A. Lazar
Publikováno v:
Genes & Development. 36:300-312
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that is a vital regulator of adipogenesis, insulin sensitivity, and lipid metabolism. Activation of PPARγ by antidiabetic thiazolidinediones (TZD) reverses insulin resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352e9a6de201ff2c31a5937ff6784307
https://doi.org/10.1101/gad.349232.121
https://doi.org/10.1101/gad.349232.121
Autor:
Yang Xiao, Kirill Batmanov, Wenxiang Hu, Kun Zhu, Alexander Y. Tom, Dongyin Guan, Chunjie Jiang, Lan Cheng, Sam J. McCright, Eric C. Yang, Matthew R. Lanza, Yifan Liu, David A. Hill, Mitchell A. Lazar
Publikováno v:
Science Translational Medicine. 15
Current therapeutic strategies for treating nonalcoholic steatohepatitis (NASH) have failed to alleviate liver fibrosis, which is a devastating feature leading to hepatic dysfunction. Here, we integrated single-nucleus transcriptomics and epigenomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ec5b9fa8bfe679f9f73e8f747f49c9
https://doi.org/10.1126/scitranslmed.adc9653
https://doi.org/10.1126/scitranslmed.adc9653
Autor:
Mitchell A. Lazar, Dongyin Guan
Publikováno v:
J Clin Invest
Circadian rhythms evolved through adaptation to daily light/dark changes in the environment; they are believed to be regulated by the core circadian clock interlocking feedback loop. Recent studies indicate that each core component executes general a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf88198f1fb08f80148dcc484576c3b4
https://doi.org/10.1172/jci148278
https://doi.org/10.1172/jci148278
Publikováno v:
Methods Mol Biol
Circadian Clocks ISBN: 9781071603802
Circadian Clocks ISBN: 9781071603802
Circadian gene transcription transmits timing information and drives cyclic physiological processes across various tissues. Recent studies indicate that oscillating enhancer activity is a major driving force of rhythmic gene transcription. Functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193641723c12b8fa86ce73091978141d
https://europepmc.org/articles/PMC8073214/
https://europepmc.org/articles/PMC8073214/