Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Dongyao Yan"'
Autor:
Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/174408689eff4e6e9ca900272ba6e6a0
Autor:
Marine Jary, Wen‐Wei Liu, Dongyao Yan, Isaac Bai, Andrea Muranyi, Elise Colle, Isabelle Brocheriou, Anthony Turpin, Nina Radosevic‐Robin, Pierre Bourgoin, Frédérique Penault‐Llorca, Romain Cohen, Dewi Vernerey, Thierry André, Christophe Borg, Kandavel Shanmugam, Magali Svrcek
Publikováno v:
Molecular Oncology, Vol 16, Iss 11, Pp 2260-2273 (2022)
In the era of immune checkpoint inhibitors, understanding the metastatic microenvironment of proficient mismatch repair/microsatellite stable (pMMR/MSS) colorectal cancer (CRC) is of paramount importance to both prognostication and the development of
Externí odkaz:
https://doaj.org/article/528753a036b940b0a01d68a276c317a4
Autor:
Qiyao Pu, Jie Qiao, Yuke Liu, Xueyan Cao, Ran Tan, Dongyao Yan, Xiaoqian Wang, Jiwei Li, Baohong Yue
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
We compared the differential expression of 15 markers in PTCL (Peripheral T-cell lymphoma) subtypes and T-CUS (T-cell clones of uncertain significance), and summarized the specific immunophenotype profiles of each subtype and its impact on prognosis.
Externí odkaz:
https://doaj.org/article/0751a0f74300480187bf6969baf1e69b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundFew studies have been performed to comprehensively analyze and summarize the immunophenotype and differential diagnosis of mature NK cell tumors, and there is often overlap between tumorigenic and reactive NK cell phenotypes. Furthermore, t
Externí odkaz:
https://doaj.org/article/23af4df23e624b41b5e60676589d4b9b
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2914-2927 (2016)
Tumor-associated macrophages play critical roles during tumor progression by promoting angiogenesis, cancer cell proliferation, invasion, and metastasis. Cysteine cathepsin proteases, produced by macrophages and cancer cells, modulate these processes
Externí odkaz:
https://doaj.org/article/c6be6da4a48e48a6aa04f985115e3a53
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Table S1: Baseline patient demographics and disease characteristics. Table S2: mRNA/IHC AREG/EREG concordance table. Figure S1: AREG/EREG IHC scatterplot. Table S3: Prognostic effect of dichotomous AREG/EREG. Table S4: AREG/EREG and RECIST response r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d26093065ca47cac56c3fafb14b7ba6
https://doi.org/10.1158/1078-0432.22478486.v1
https://doi.org/10.1158/1078-0432.22478486.v1
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Purpose:High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3918d1658590fe73e85875c77ed53656
https://doi.org/10.1158/1078-0432.c.6529961
https://doi.org/10.1158/1078-0432.c.6529961
Autor:
Auranuch Lorsakul, Andrea Muranyi, Uday Kurkure, Kien Nguyen, Wen-Wei Liu, Isaac Bai, Jennifer H. Barrett, Christoph Guetter, Kandavel Shanmugam, Matthew T. Seymour, Philip Quirke, Michael Barnes, Dongyao Yan, Jenny F. Seligmann, Susan D. Richman, Zuo Zhao, Nicholas P. West, Xiao-Meng Xu, Xingwei Wang, Liping Zhang, James R. Martin, Faye Elliott, Michael Shires, Christopher J.M. Williams, Sarah Brown, Judith Pugh, Shalini Singh
Publikováno v:
Clinical Cancer Research. 27:3422-3431
Purpose: High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice
Autor:
Bahar Saberzadeh-Ardestani, Rondell P. Graham, Qian Shi, Eze Ahanonu, Sara McMahon, Crystal Williams, Antony Hubbard, Wenjun Zhang, Andrea Muranyi, Dongyao Yan, Kandavel Shanmugam, Frank A. Sinicrope
Publikováno v:
Cancer Research. 83:6648-6648
Background: Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of patients with deficient DNA mismatch repair (d-MMR) metastatic colorectal cancer (CRC), yet less than half of patients receive clinical benefit. We hypothesized that
Autor:
Thiago Vidotto, Isaac Bai, Jeffrey J. Tosoian, Dongyao Yan, Daniela C. Salles, Shalini Singh, Andrea Muranyi, Tamara L. Lotan, Farzana A. Faisal, Liana B. Guedes, Kandavel Shanmugam
Publikováno v:
The Journal of Molecular Diagnostics : JMD
This study leveraged a gene-protein assay to assess MYC and PTEN status at prostate cancer biopsy and examined the association with adverse outcomes after surgery. MYC gain and PTEN loss were simultaneously assessed by chromogenic in situ hybridizati