Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Dongwei, Xu"'
Autor:
Dongwei Xu, Xiaoye Qu, Tao Yang, Mingwei Sheng, Xiyun Bian, Yongqiang Zhan, Yizhu Tian, Yuanbang Lin, Yuting Jin, Xiao Wang, Michael Ke, Longfeng Jiang, Changyong Li, Qiang Xia, Douglas G. Farmer, Bibo Ke
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1843-1855 (2024)
Abstract Innate immune activation is critical for initiating hepatic inflammation during nonalcoholic steatohepatitis (NASH) progression. However, the mechanisms by which immunoregulatory molecules recognize lipogenic, fibrotic, and inflammatory sign
Externí odkaz:
https://doaj.org/article/971a8340ac1343509d1ccc9d924aa126
Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury
Autor:
Xiaoye Qu, Dongwei Xu, Tao Yang, Yizhu Tian, Christopher T. King, Xiao Wang, Mingwei Sheng, Yuanbang Lin, Xiyun Bian, Changyong Li, Longfeng Jiang, Qiang Xia, Douglas G. Farmer, Bibo Ke
Publikováno v:
Redox Biology, Vol 79, Iss , Pp 103455- (2025)
Dishevelled 2 (Dvl2) is a key mediator of the Wingless/Wnt signaling pathway that regulates cell proliferation, migration, and immune function. However, little is known about the role of macrophage Dvl2 in modulating NOD1-mediated pyroptosis and hepa
Externí odkaz:
https://doaj.org/article/5c769020c9d04f8282829ed0a437e50c
Autor:
Junzhe, Jiao, Meng, Li, Weifan, Huang, Min, Xu, Jiacheng, Lin, Yihan, Qian, Ke, Zhen, Fang, Wang, Dongwei, Xu, Hailong, Wu, Xiaoni, Kong
Publikováno v:
In International Immunopharmacology 15 February 2024 128
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Objective Knowledge, attitude and practice (KAP) models are essential tools for assessing healthcare professionals’ understanding, beliefs and behaviours towards specific health issues. This study aimed to explore the KAP of Chinese doctors in diag
Externí odkaz:
https://doaj.org/article/4ae588caa2f24d6ca57f9660ad275b7f
Autor:
Xiaoye Qu, Tao Yang, Xiao Wang, Dongwei Xu, Yeping Yu, Jun Li, Longfeng Jiang, Qiang Xia, Douglas G. Farmer, Bibo Ke
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100879- (2023)
Background & Aims: Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) is a central player in triggering necroptotic cell death. However, whether macrophage RIPK3 may regulate NOD1-dependent inflammation and calcineurin/transient receptor
Externí odkaz:
https://doaj.org/article/ff345f1706304f7a9531be654746bcd1
Autor:
Min-Er Zhong, Xin Duan, Ma-yi-di-li Ni-jia-ti, Haoning Qi, Dongwei Xu, Du Cai, Chenghang Li, Zeping Huang, Qiqi Zhu, Feng Gao, Xiaojian Wu
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background This study aimed to develop a radiogenomic prognostic prediction model for colorectal cancer (CRC) by investigating the biological and clinical relevance of intratumoural heterogeneity. Methods This retrospective multi-cohort stud
Externí odkaz:
https://doaj.org/article/2f933b3cd3f649239a4ef4b62a4686a4
Autor:
Dongwei Xu, Alec Vincent, Andrés González-Gutiérrez, Benjamin Aleyakpo, Sharifah Anoar, Ashling Giblin, Magda L Atilano, Mirjam Adams, Dunxin Shen, Annora Thoeng, Elli Tsintzas, Marie Maeland, Adrian M Isaacs, Jimena Sierralta, Teresa Niccoli
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010893 (2023)
Brains are highly metabolically active organs, consuming 20% of a person's energy at resting state. A decline in glucose metabolism is a common feature across a number of neurodegenerative diseases. Another common feature is the progressive accumulat
Externí odkaz:
https://doaj.org/article/44d952c3a1cc4820a8897d05251cf851
Autor:
Dongwei Xu, Xiaoye Qu, Yizhu Tian, Zhao Jie, Zhifeng Xi, Feng Xue, Xueyun Ma, Jianjun Zhu, Qiang Xia
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Notch signaling is highly conserved and critically involved in cell differentiation, immunity, and survival. Activation of the Notch pathway modulates immune cell functions during the inflammatory response. However, it remains unk
Externí odkaz:
https://doaj.org/article/ecd84d43e56b431cb0cad7125c0c48d5
Autor:
Lifeng Huang, Dongwei Xu, Yawei Qian, Xiaoqiang Zhang, Han Guo, Meng Sha, Rui Hu, Xiaoni Kong, Qiang Xia, Yi Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Improved understanding of the stemness regulation mechanism in intrahepatic cholangiocarcinoma (ICC) could identify targets and guidance for adjuvant transarterial chemoembolization (TACE). Methods TCGA database was excavated to i
Externí odkaz:
https://doaj.org/article/8965e277d2f441089ac5a9db9b8af039
Publikováno v:
Sensors, Vol 23, Iss 23, p 9601 (2023)
Traffic state data are key to the proper operation of intelligent transportation systems (ITS). However, traffic detectors often receive environmental factors that cause missing values in the collected traffic state data. Therefore, aiming at the abo
Externí odkaz:
https://doaj.org/article/069cd4cb9ef0442eb2394d27d6ec1d3c