Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dongsheng Shang"'
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Alzheimer's disease (AD) is the leading cause of dementia. With no reliable treatment that delays or reverses the progress of AD, effective medical drugs, and interventions for AD treatment are in urgent need. Clinical success for patient
Externí odkaz:
https://doaj.org/article/08de1505c45e4c198e8d0039ab157893
Autor:
Chunxiu Lin, Peng Liu, Chaowen Shi, Lipeng Qiu, Dongsheng Shang, Ziwen Lu, Zhigang Tu, Hanqing Liu
Publikováno v:
Fundamental & Clinical Pharmacology. 37:194-214
The susceptibility of cells to DNA damage and their DNA repair ability are crucial for cancer therapy. Homologous recombination is one of the major repairing mechanisms for DNA double-strand breaks. Approximately half of ovarian cancer (OvCa) cells h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c133b6d5e1ac308981373d122c230b90
https://doi.org/10.1111/fcp.12834
https://doi.org/10.1111/fcp.12834
Publikováno v:
Fundamental & Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2927bd6b45182a2efa55014d8c137ec
https://doi.org/10.1111/fcp.12915
https://doi.org/10.1111/fcp.12915
Publikováno v:
Fundamentalclinical pharmacology.
Hematopoietic stem cells (HSCs) produce all blood cell lineages and maintain life-long hematopoiesis. However, the self-renewal ability and differentiation capacity of HSCs reduces with age. The senescence of HSCs can lead to the imbalance of hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a963403440c1de362f29625b047d4c8
https://pubmed.ncbi.nlm.nih.gov/36582074
https://pubmed.ncbi.nlm.nih.gov/36582074
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(5)
Simian virus 40 (SV40) is a potentially oncogenic virus of monkey origin. Transmission, prevalence, and pathogenicity rates of SV40 are unclear, but infection can occur in humans, for example individuals with high contact with rhesus macaques and ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f54e0cc633f94699bae10b7d836a1aa
https://pubmed.ncbi.nlm.nih.gov/35429286
https://pubmed.ncbi.nlm.nih.gov/35429286
Autor:
Han Xu, Hanqing Liu, Ruyan Li, Lu Ziwen, Zhiquan Liang, Lanlan Liu, Mengchen Ji, Yuhua Yang, Yibang Zhang, Mingxiang Shen, Dewan Ren, Peng Liu, Zhigang Tu, Dongsheng Shang
Publikováno v:
Anti-Cancer Drugs. 30:554-561
Ovarian cancer is a heterogeneous disease with complex molecular and genetic hallmarks. Benefitting from profound understanding of molecular mechanisms in ovarian cancer pathogenesis, novel targeted drugs have been actively explored in preclinical st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3446e4e0e655213a80418fae00fa2704
https://doi.org/10.1097/cad.0000000000000793
https://doi.org/10.1097/cad.0000000000000793
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Alzheimer's disease (AD) is the leading cause of dementia. With no reliable treatment that delays or reverses the progress of AD, effective medical drugs, and interventions for AD treatment are in urgent need. Clinical success for patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9625301a98a57e16e11bfe9ae9f459
https://pubmed.ncbi.nlm.nih.gov/33013631
https://pubmed.ncbi.nlm.nih.gov/33013631
Autor:
Shen Yanting, Lu Ziwen, Ya Ding, Hanqing Liu, Zhigang Tu, Wu Yanfang, Feifei Zhu, Dongsheng Shang, Chunyin Zhu
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 45:452-460
Cellular senescence is a state of irreversible cell growth arrest. Increasing evidence suggests that cellular senescence contribute to tumour suppression in vivo. However, only a few anti-cancer drugs have been discovered to induce cellular senescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78be1e54155bcdf059ad0585f7168cd6
https://doi.org/10.1111/1440-1681.12891
https://doi.org/10.1111/1440-1681.12891
Autor:
Zhigang Tu, Hanqing Liu, Lipeng Qiu, Yanyan Li, Zhicong Zhao, Guoyue Yuan, Chang Guo, Dongsheng Shang
Publikováno v:
Life sciences. 238
Aims Gastric cancer (GC) is a common cancer with a relatively low survival rate. Cellular senescence, a potent anti-cancer mechanism, is naturally occurred, and can be induced by chemotherapeutic agents. We sought to explore new compounds against GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c659d8edb9ceb0e8cd129ffeb6f48ef
https://pubmed.ncbi.nlm.nih.gov/31639393
https://pubmed.ncbi.nlm.nih.gov/31639393
Autor:
Lu Ziwen, Yi-Hang Wu, Zhigang Tu, Dongsheng Shang, Mengchen Ji, Hanqing Liu, Han Xu, Lipeng Qiu
Publikováno v:
Life sciences. 231
Hepatocellular carcinoma (HCC), a leading cause of cancer-related death with high invasive and metastatic potential, has a low survival rate. To improve the survival and quality of life in HCC patients, it is urgently needed to explore novel biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47ba5eef20a8023de0b1ace7cd50818
https://pubmed.ncbi.nlm.nih.gov/31319086
https://pubmed.ncbi.nlm.nih.gov/31319086