Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Dongsheng, Pei"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-16 (2024)
Abstract 5-Fluorouracil (5-FU) is the primary treatment option for advanced gastric cancer. However, the current challenge lies in the absence of validated biomarkers to accurately predict the efficacy and sensitivity of 5-FU in individual patients.
Externí odkaz:
https://doaj.org/article/235dd318b7af451188ed3342d137adcc
Publikováno v:
Cancer Reports, Vol 7, Iss 8, Pp n/a-n/a (2024)
ABSTRACT Background Integrin‐Binding Sialoprotein (IBSP) has been implicated in tumor progression across various cancers. However, the specific role of IBSP in breast cancer remains underexplored. There is a need to investigate the mechanisms by wh
Externí odkaz:
https://doaj.org/article/86aca7c3785a49fb9d31138b5543127c
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 54, Iss , Pp 101009- (2024)
Background: Lipid metabolism and regulated cell death (RCD) play a role in the remodeling of tumor immune microenvironment and regulation of cancer progression. Since the underlying immune mechanisms of colon cancer remain elusive, this study aims to
Externí odkaz:
https://doaj.org/article/ad3f2fb0e6c54717b2b09d62f16cf07b
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-21 (2024)
Abstract Background The tumor immune microenvironment (TIME) is an important regulator of tumor progression, growth and metastasis. In addition, tumor metastasis is one of the principal obstacles to the treatment of colorectal cancer (CRC). Circular
Externí odkaz:
https://doaj.org/article/9a40fa1d32d542088cd54b067d9a1da8
Autor:
Meijian Liao, Xiaolin Sun, Wendan Zheng, Mengdi Wu, Yifan Wang, Jia Yao, Yu Ma, Shoucui Gao, Dongsheng Pei
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Lysine crotonylation (Kcr) is up-regulation in colorectal cancer (CRC) tissues, while its specific contribution remains uncertain. This study aimed to elucidate the role and mechanism of crotonylation on Lys27 of histone H3 (H3K27
Externí odkaz:
https://doaj.org/article/024ee16b9c51481eb926fa21c6677fe1
Autor:
Bowen Liu, Angxi Song, Pengkun Gui, Jin Wang, Yaojie Pan, Chao Li, Shuai Li, Yi Zhang, Tao Jiang, Yixin Xu, Dongsheng Pei, Jun Song
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-16 (2023)
Abstract Long noncoding RNAs (lncRNAs) play critical roles in tumorigenesis and tumor metastasis. However, the underlying mechanisms of lncRNAs in colorectal cancer (CRC) need further exploration. By using data from The Cancer Genome Atlas (TCGA) and
Externí odkaz:
https://doaj.org/article/5d37ec2228974bcb9b98c692ad530de3
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Tumors frequently evade immune surveillance through multiple pathways to escape T cell recognition and destruction. Previous studies indicated that lipid metabolism alteration could affect the anti-tumor immunity of cancer cells. Nonethel
Externí odkaz:
https://doaj.org/article/5ba6aa481242493d96f57264cffaad03
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 5, Pp 573-590 (2022)
The COP9 signalosome (CSN) is a highly conserved protein complex composed of 8 subunits (CSN1 to CSN8). The individual subunits of the CSN play essential roles in cell proliferation, tumorigenesis, cell cycle regulation, DNA damage repair, angiogenes
Externí odkaz:
https://doaj.org/article/2672ab4f8e6345fabff6212d6130ec9e
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract ORP5, a lipid transporter, has been reported to increase the metastasis of several cancers. However, the potential mechanisms of ORP5 in renal cell carcinoma (RCC) remain unclear. In this study, we demonstrated that ORP5 was commonly overexp
Externí odkaz:
https://doaj.org/article/c5b46c4afbaa4c6cbaa887c6ec40a48d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
DNA damage plays an essential role in the initiation and development of colon cancer. Histone crotonylation is a newly discovered post-translational modification that is thought to promote gene expression. Whether histone crotonylation plays a role i
Externí odkaz:
https://doaj.org/article/ebb49727d1334cca8b07260d34f695fe